Suprastin tab 25mg 40 pc

Description

Composition
Active substance:
1 tablet contains: Chloropyramine gidrohlorida- 25 mg.
Excipients:
Stearic acid, gelatin, sodium carboxymethyl starch (type A), talc, potato starch, lactose monohydrate (116 mg).
Description:
White or grayish-white pills in the form of a disk with beveled, engraved with “SUPRASTIN” on one side of the tablet and the notch on the other side, with little or no odor.
Product form:
Tablets of 25 mg. 20 tablets in brown glass bottles with polyethylene caps. The bottle is packed in a cardboard box, together with instructions for medical use.
10 tablets in blister. 2 of the blister pack in a cardboard box, together with instructions for medical use.
20 tablets in blister. 1 blister pack in a cardboard box, together with instructions for medical use.
Contraindications
Hypersensitivity to the drug component, an acute attack of asthma, children under 3 years (for a given dosage form), pregnancy and lactation, laktazy deficiency, lactose intolerance, glucose / galactose malabsorption (as the tablet contains 116 mg of lactose monohydrate) .
Precautions: angle-closure glaucoma, urinary retention, prostatic hyperplasia of the liver and / or kidney disease, cardiovascular disease, elderly patients.
Dosage
25 mg
Indications
Urticaria, serum sickness, seasonal and perennial allergic rhinitis, conjunctivitis, contact dermatitis, itching, acute and chronic eczema, atopic dermatitis, food and drug allergies, allergic reactions to insect bites.
Angioedema (Quincke’s edema) as an adjuvant.
Interaction with other drugs
The drug enhances the effect of drugs: barbiturates, M-anticholinergics, opioid analgesics. MAO inhibitors can enhance and prolong the effect of anticholinergic Chloropyramine. When combined with ototoxic medications Suprastin® may mask the early symptoms ototoksichnosti.
Antihistamine agents may distort the results of allergy skin samples, so a few days before the planned test of the administration of drugs of this type should be discontinued.
Overdose
Symptoms: hallucinations, anxiety, ataxia, impaired coordination of movements, athetosis, convulsions. In young children agitation, anxiety, dry mouth, fixed dilated pupils, flushing of the face, sinus tachycardia, urine retention, fever, coma. In adults, fever and facial flushing are observed impermanent, after the commencement of the period followed by cramps and poslesudorozhnaya depression, coma.
Treatment: prior to 12 hours after ingestion of the drug to a gastric lavage (note that inhibits gastric emptying effect of an anticholinergic drug). Displaying the same activated carbon. Necessary to monitor blood pressure and respiration parameters. Symptomatic therapy. Resuscitation.
A specific antidote is not known.
pharmachologic effect
Pharmacological group:
Antiallergic agent – H1 – histamine receptor blocker.
Pharmacodynamics:
Chloropyramine – chlorinated analog tripelennamine (piribenzamina) – a classical antihistamine belonging to Groups ethylenediamine antihistamines.
Blocker H1-histamine receptor has antihistaminic and m-anticholinergic action, possesses antiemetic effect, spasmolytic and peripheral moderate anticholinergic activity.
Pharmacokinetics:
When taken orally, it is almost completely absorbed from the gastrointestinal tract (GIT). Therapeutic effect hlorpiramina develops within 15-30 minutes after oral administration, reaching a maximum during the first hour after administration and lasts for at least 3-6 hours. Well distributed in the body, including the central nervous system (TSNC).
It is extensively metabolized by the liver. They write mainly kidneys.
In children, excretion of the drug faster than in adult patients.
Pregnancy and breast-feeding
Failed to carry out adequate, with proper control trials of antihistamines in pregnant women. In accordance with this Suprastin taken during pregnancy (especially during the first trimester and the last month) should be only if the potential benefit to the mother outweighs the potential risk to the fetus.
If necessary, use during lactation should decide on the suspension of breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Side effects usually are rare, temporary, run after discontinuation of the drug. From the blood and lymphatic system: very rare: leukopenia, agranulocytosis, hemolytic anemia, and other changes in the cellular composition of the blood.
CNS: drowsiness, fatigue, dizziness, nervous excitement, tremors, headache, euphoria, convulsions, encephalopathy.
On the part of the organ of vision: blurred vision, glaucoma, increased intraocular pressure.
Cardio-vascular system: decrease in blood pressure, tachycardia, arrhythmia. It was not always a direct relationship of these side effects from taking the drug.
On the part of the gastrointestinal tract: abdominal discomfort, dry mouth, nausea, vomiting, diarrhea, constipation, loss or increase of appetite, pain in the upper abdomen.
On the part of the musculoskeletal and connective tissue disorders: muscle weakness.
The kidneys and the urinary tract: difficulty in urination, urinary retention.
Others: photosensitivity, allergic reactions.
If any of the above-mentioned effects, stop taking the drug and consult a doctor immediately.
special instructions
When combined with ototoxic medications Suprastin® may mask the early symptoms ototoksichnosti.
Liver and kidneys may require a change (decrease) of the dose, and therefore the patient should inform the physician of the presence of his liver or kidney disease. Taking the drug at night can exacerbate symptoms reflyukc esophagitis.
Syprastin® may enhance the effects of alcohol on the central nervous system, in connection with what during treatment Suprastin® should avoid alcohol.
Long-term use of antihistamines may impair the blood system and hematopoiesis (leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia). If during a long application observed unexplained fever, laryngitis, pallor, jaundice, ulcerations in the mouth, bruising, unusual bleeding continuing and long, it is necessary to carry out clinical analysis of blood by determining the number of formed elements. If test results indicate a change in blood formula, the drug is stopped.
Effect of the drug for medical use in driving ability, mechanisms: preparation, especially in the initial period of treatment, can cause drowsiness, fatigue and dizziness. Therefore, in the initial period, the duration of which is determined individually, prohibited driving vehicles or performing work associated with an increased risk of accidents. Thereafter the driving restrictions transportation and work with the mechanisms of the physician must be determined for each patient individually.
Storage conditions
At a temperature of 15-25 ° C, the reach detey place.
Dosing and Administration
The tablets are taken orally during meal time, without chewing and drinking plenty of water.
Adults: appoint 1 tablet 3-4 times a day (75-100 mg daily).
children:
At the age of 3 to 6 years: 1/2 tablet 2 times a day;
At the age of 6 to 14 years old: 1/2 tablet (12.5 mg) 2-3 times a day.
The dose can be gradually increased in the absence of side effects in the patient, but the maximum dose should never exceed 2 mg / kg body weight.
The duration of treatment depends on the symptoms of the disease, its duration and current.
The elderly, malnourished patients: application Suprastin® preparation requires special care, since in these patients, antihistamines are more likely to cause side effects (dizziness, drowsiness).
Patients with impaired liver functions may require dose reduction due to the decrease metabolism of the active ingredient of the drug for liver diseases.
Patients with impaired renal function: may be necessary to change the mode of drug administration and the dose reduction due to the fact that the active component is mainly excreted via the kidneys.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist