Troksevazin neo-gel naruzhn.prim I 2% 40g

Description

Composition
Active substance:
1 g of gel contains: 20 mg Troxerutin, dexpanthenol 50 mg, heparin sodium 1.7 mg (corresponding to 300 ME) ;.
Excipients:
Carbomer 7 mg, 100 mg propylene glycol, methyl tilparagidroksibenzoat 0.8 mg propyl parahydroxybenzoate 0.2 mg, 4.2 mg trolamine, purified water to 1 g
Description:
Clear or almost clear gel from yellowish to greenish-yellow in color.
Product form:
Gel for external application.
40 g of the drug to the membrane aluminum tube, 40 g or 100 g in a membrane laminate tube. Each tube together with instructions for use placed in a cardboard box.
Contraindications
Upcoming infected wounds or wounds with copious exudation at the site of application; hypersensitivity to the drug; age younger than 18 years (experience of the application is missing).
Indications
Varicose veins.
Chronic venous insufficiency with symptoms such as swelling and pain in the legs; a feeling of heaviness, bloodshot, tired legs; spider veins and spider veins, cramps, paresthesias.
Thrombophlebitis.
Periflebit.
Varicose dermatitis.
Pain and swelling traumatic nature (for bruises, sprains, trauma).
Interaction with other drugs
Neo Troxevasin drug interactions with other drugs is not revealed.
Overdose
Overdosing is unlikely due to the low systemic absorption of active components of the gel.
pharmachologic effect
Pharmacological group:
Anticoagulant means of direct action for local application + other drugs.
Pharmacodynamics:
Troksevazin® Neo – combined preparation for external application. The action is due to its composition of ingredients:
Troxerutin – angioprotective means. It has a P-vitamin activity: providing venotonic, venoprotektornoe, anti-inflammatory, anticoagulant and an antioxidant effect. Reduces the permeability and fragility of capillaries, increases their tone. Increases payment for the vascular wall. Contributes to the normalization of microcirculation and trophic tissue, reduces congestion. Heparin – anticoagulant direct action, a natural anticoagulant factor in the body. Prevents thrombosis, activates the fibrinolytic properties of blood, improves local blood flow.
Anti-inflammatory action, promotes the regeneration of connective tissue due to inhibition of hyaluronidase activity.
Dexpanthenol – provitamin B5 – the skin is transformed into pantothenic acid that is part of coenzyme A, which plays an important role in the processes of acetylation and oxidation. Improving metabolic processes, dexpanthenol promotes regeneration of damaged tissues; improves absorption of heparin.
Pharmacokinetics:
When applied topically active substances quickly absorbed by the skin.
Heparin is stored in the upper layers and actively binds to skin proteins. When applied topically penetrate small amount of heparin in the systemic circulation, without causing systemic effects without causing any changes of blood coagulation parameters. It does not cross the placental barrier.
Dexpanthenol penetrates all layers of the skin and converted into pantothenic acid, binds to plasma proteins (mostly with beta-globulin and albumin). Pantothenic acid is not subjected to metabolism in the body and excreted unaltered. Troxerutin 30 minutes found in the dermis, and after 2-5 hours in the subcutaneous adipose tissue. Troxerutin penetration into the systemic circulation is clinically insignificant.
Pregnancy and breast-feeding
Troksevazin Neo approved for use during pregnancy and lactation (breastfeeding).
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions: skin rash, pruritus (at the site of drug).
special instructions
Avoid contact with open wounds, mucous membranes and eyes!
* Neo Troxevasin drug is not intended for use in ophthalmology, for vaginal and rectal administration.
Effect on driving ability and / or work with other mechanisms.
On the background of the drug any adverse effect on the ability to drive or other technical means was not observed.
Storage conditions
Store at a temperature not higher than 25 ° C. Keep out of the reach of children!.
Dosing and Administration
Outwardly! The gel was applied thinly to the affected area two times a day, morning and evening, evenly distributed over the surface of the skin with light rubbing movements until absorbed. If necessary, the gel can be applied under bandages or elastic stockings.
Treatment success preparation largely depends on its regular use for a long time. The course of treatment is 2-3 weeks. The need for more long-term treatment determined by the attending physician.
Second course of treatment is recommended 2-3 times a year.
It recommended in Combination with capsules Troxevasin to gain exposure.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist