Citovir-3 syrup for children 50ml

Description

Composition
Active substance:
1 ml of syrup contain: alpha-glutamyl-tryptophan (Timogen sodium based on timogen) 0.15 mg, 12 mg ascorbic acid, bendazol hydrochloride [Dibazol] 1.25 mg.
Excipients:
Sucrose, purified water.
Description:
Syrup from colorless to yellow.
Product form:
Syrup [for children]. 50 ml amber glass vial. The vial was sealed with a plastic cover with a tamper-evident plastic lid or with a tamper-evident and child protection.
One vial was placed in a pile of cardboard.
instructions for use or put into the package in a folded leaflet is placed under the opening portion of the label. The pack put dispensing device: measuring cup or spoon dosing or dosing pipette.
Contraindications
Hypersensitivity to the drug, diabetes, pregnancy, children up to 1 year. If necessary, please consult your doctor before taking the drug.
Consult your doctor before taking this medication if you have hypotension.
Dosage
0.15 mg + 12 mg + 1.25 mg / ml
Indications
Prevention and comprehensive treatment of influenza and acute respiratory viral infections in children from one year.
Interaction with other drugs
Interaction of alpha-glutamyl-tryptophan with drugs have been identified. Bendazol prevents an increase in total peripheral vascular resistance due to the use of non-selective beta-blockers. Enhances the hypotensive (blood pressure lowering) effect of antihypertensive and diuretic drugs. Phentolamine enhances the hypotensive effect bendazol.
Ascorbic acid increases in the blood concentration of antimicrobials tetracycline and penicillin. It improves the intestinal absorption of iron preparations (Fe). Reduces the effectiveness of heparin and indirect anticoagulants. Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline water reduces its absorption and assimilation. While the use of ASA increases urinary excretion of ascorbic acid and reduced excretion of ASA. ASA reduces absorption of ascorbic acid is about 30%. Ascorbic acid increases the risk of crystalluria when using preparations containing acetylsalicylic acid (ASA) and sulfonamides short-acting, slow excretion by the kidneys acids, increases the excretion of drugs having an alkaline reaction (including alkaloids), reduces blood levels of oral contraceptives. When applied simultaneously reduces the chronotropic isoprenaline effect. Reduces the therapeutic action of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants. Barbiturates, primidone and increase the excretion of ascorbic acid in urine.
Simultaneous use with antiviral medicines and symptomatic treatment of influenza and SARS.
Check with your doctor if you are taking these in the section or other drugs.
Overdose
Overdose cases are not described.
pharmachologic effect
Pharmacological group:
Immunostimulatory agent.
Pharmacodynamics:
The drug is a causal agent and immunostimulatory therapy has mediated antiviral action against influenza virus A and B, and other viruses that cause acute respiratory diseases. The drug reduces the severity of the main clinical symptoms of influenza and SARS, as well as reduces the duration of symptoms of the disease symptoms.
Bendazol induces in the organism the production of endogenous interferon has immunomodulatory effects (normalizes the immune response). Enzymes which induced production of interferon in the cells of various organs, inhibit viral replication.
Alpha-glutamyl-tryptophan (timogen) is a synergist bendazol immunomodulatory action of normalizing the T-cell-mediated immunity.
Ascorbic acid activates humoral immunity, normalizes capillary permeability, thereby reducing inflammation, and manifests antioxidant, neutralizing oxygen radicals that accompany inflammatory process, increases resistance to infection.
Pharmacokinetics:
When administered drug is completely absorbed from the gastrointestinal tract. Bendazol Bioavailability – 80% alpha-glutamyl-tryptophan – no more than 15%, ascorbic acid – up to 70%. Ascorbic acid is absorbed in the GI tract (primarily in the jejunum). Relationship to plasma proteins – 25%. TSmah after ingestion -4 hours. Easily penetrate leukocytes, platelets, and then all tissues permeates through the placenta. Gastrointestinal diseases (peptic ulcer and 12-finger ulcers, disorders of intestinal motility, worm infestation, giardiasis), the use of vegetable and fruit juices, drinking alkaline reduced binding of ascorbic acid in the gut. Ascorbic acid is metabolized primarily in the liver dezoksiaskorbinovuyu, hereinafter diketogulonovuyu and oxaloacetic acid. Excreted by the kidneys, through the intestines, sweat, breast milk unchanged and as metabolites. Bendazol biotransformation products in the blood are the two conjugate formed due to methylation of the imidazole ring karboetoksilirovaniya imino bendazol 1-methyl-2-Benzylbenzimidazol 1- and 2-carboethoxy-Benzylbenzimidazol. bendazol metabolites are excreted in the urine. Alpha- glutamyl-tryptophan, under the action of peptidases split into L-glutamic acid and L-tryptophan, which are used by the body in protein synthesis.
Pregnancy and breast-feeding
During pregnancy, the drug is not recommended due to insufficient clinical data. During the period of breastfeeding application is possible if the expected benefit to the mother outweighs the potential risk to the child. If necessary, the administration of the drug during breast-feeding, please consult your physician.
Conditions of supply of pharmacies
Without recipe.
side effects
Perhaps short-term reduction in blood pressure. Allergic reactions: urticaria. In these cases, use of the drug is stopped and administered symptomatic treatment, antihistamines. Consult with your doctor if you have appeared mentioned side effects or other side effects not mentioned in the instructions.
If the side effects listed in the instructions, compounded inform your doctor.
special instructions
After repeated course is recommended to control the concentration of glucose in blood.
Effects on ability to drive vehicles, mechanisms:
The drug does not affect the ability to drive, work with moving machinery and engage in other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
Scheme therapeutic and prophylactic use identical.
Inside for 30 minutes before eating.
Children aged 1 to 3 years – 2 ml 3 times a day;
Children aged 3 to 6 years – 4 ml 3 times a day;
Children aged 6 to 10 years – in 8 ml 3 times per day;
Children under the age of 10 – 12 ml 3 times a day.
application rate – 4 days. If after 3 days of treatment there is no improvement or symptoms are aggravated, or there are new symptoms, you should consult with your doctor.
Preventive course is repeated in 3-4 weeks if necessary.
Take the drug only according to the application and in those doses which are specified in the instruction. Use the product only according to the indications specified in the instructions. If necessary, please consult your doctor before taking the drug.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist