Akriderm ointment for naruzhn.prim-I 0.05% 15g tube

Description

Composition
Active substance:
100 g of ointment contains: betamethasone dipropionate in terms of 100% substance – 0,064 g, equivalent to 0.05 g of betamethasone ;.
Excipients:
: Propyl parahydroxybenzoate – 0.05 g, liquid paraffin (vaseline oil) – 4 g isopropyl – 1 g Petrolatum – 100 g
Description:
Translucent ointment from white to white with a yellowish tinge.
Product form:
Ointment for external use 0.05%. 15 or 30 g in a tube of aluminum. Each tube together with instructions for use in a stack of cardboard.
Contraindications
Hypersensitivity to betamethasone or other drug compounds. Lupus, cutaneous manifestations of syphilis, bacterial, fungal, viral (varicella, herpes simplex), skin diseases, skin postvaktsinalnyereaktsii, open wounds, leg sores, rosacea, acne vulgaris, skin cancer,
nevus, sebaceous cyst, melanoma, hemangioma, xanthoma, sarcoma, lactation and detskiyvozrast up to 1 year.
Carefully
With prolonged use, or applied to a large surface: cataract, diabetes, glaucoma, tuberculosis.
Dosage
0.64 mg / g
Indications
Skin diseases that are amenable glyukokortikosteroidnoyterapii: atopic dermatitis; allergic contact dermatitis; eczema (various forms); contact dermatitis (including professional) other non-allergic dermatitis (including solar radiation and dermatitis); reactions to insect stings; psoriasis; bullous dermatoses; discoid lupus erythematosus; lichen planus; mnogomorfnaya exudative erythema; itching of various etiology.
Interaction with other drugs
Drug interactions with other drugs is not revealed.
Overdose
Acute overdose is highly unlikely, however, when excessive or prolonged application of the drug overdose, chronic possible, accompanied by signs of Cushing: hyperglycemia, glycosuria, reversible depression of adrenocortical function, a manifestation of Cushing’s syndrome. Treatment: It is recommended a gradual withdrawal of the drug and, if necessary, carrying out symptomatic treatment.
pharmachologic effect
Pharmacological group:
Glucocorticosteroids for local use.
Pharmacodynamics:
Akriderm® – glucocorticosteroid for outdoor use. Has anti-inflammatory, anti-allergic, antiekssudativnoe, sosudo-
narrows, antipruritic, and antiproliferative effects. Inhibits nakoplenieleykotsitov, release of lysosomal enzymes and pro-inflammatory mediators in inflammation inhibits phagocytosis, reduced vascular tissue permeability, prevents the formation of inflammatory edema. When applied to the skin surface, the drug has a rapid and strong action the inflammation, reducing the severity of objective symptoms (erythema, edema,
lichenification) and subjective sensations (itching, irritation, pain).
Pharmacokinetics:
When cutaneous application of the drug in the therapeutic dozahtransdermalnoe absorption of the active substance in the blood is very small. The use of occlusive dressings, skin diseases and inflammation povyshayuttransdermalnoe betamethasone absorption, which can lead to an increase riskarazvitiya systemic side effects.
Pregnancy and breast-feeding
topical glucocorticosteroids safety has not been established in pregnant women; prescription drugs of this group during the period of pregnancy is justified only if the potential benefit to the mother outweighs the potential risk to the fetus. During pregnancy, this group of drugs should not be used in high doses for a long time. If necessary, use during lactation rekomenduetsyaprekratit breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
As a rule, it has slight character. When external application of glucocorticosteroids can be observed: itching, burning sensation, irritation, dryness, folliculitis, hypertrichosis, striae, aknepodobnye rash ( “steroid” blackheads), hypopigmentation, perioral dermatitis, allergic contact dermatitis. With prolonged use, and the use of occlusive dressings – maceration of the skin, secondary infection, skin atrophy, local hirsutism, telangiectasia, heat rash, purpura. When applied to a large surface of the body, mainly in children, may cause systemic side effects of corticosteroids (hyperglycemia, glucosuria, reversible inhibition of the function of the adrenal cortex, the manifestation of the syndrome Cushing) .If the appearance of adverse reactions not described in the instructions, you should consult your doctor .
special instructions
Not recommended for long-term outdoor use of the drug to the skin of the face, since it is possible the development of rosacea, perioral dermatitis and acne. The course of treatment should not exceed 5 days. Akriderm® ointment is not intended for use in ophthalmology. Avoid getting product in eyes. If the product enters the mucous membrane of the eye may develop cataract, glaucoma, fungal eye infections and exacerbation of herpes infection. For prolonged treatment, when applied to extensive skin preparation surface as well as in the armpits and groin folds when using occlusive dressings, diapers possible systemic absorption glyukokortiko- steroids. Children from 1 year the drug is prescribed only under strict indications and under medical supervision, as may develop systemic side effects associated with betamethasone. In applying the drug on extensive surfaces and / or under an occlusive dressing is possible to suppress the hypothalamic-pituitary-adrenal system and the development of Cushing’s symptoms can be observed decrease in excretion of growth hormone, increased intracranial pressure. In applying the ointment in children aged 1 year and older is necessary to limit the total duration of treatment and exclude activities leading to increased bone resorption and absorption (Warming, fixing and occlusive dressings, diapers).
The effect on the ability to operate vehicles, machinery
Does not affect.
Storage conditions
At a temperature of 15 to 25 C.
Keep out of the reach of children.
Dosing and Administration
Outwardly. Akriderm® ointment applied thinly to the affected area 2 times a day – morning and evening, gently rubbing. In areas with thicker skin (e.g., elbows, hands and feet), and the location from which the drug is easily erased, Akriderm® ointment may be applied more frequently. The duration of treatment depends on the efficacy and tolerability of therapy and is typically no more than 4 weeks. During the year, the possibility of multiple repetition of therapy.
If clinical improvement does not occur, it is necessary to specify the diagnosis.
In children and in patients with lesions of the skin treatment should not exceed 5 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist