Zinerit lotion 30ml fl / + solvent + powder applicator /

Description

Composition
Active substance:
1 vial (30 ml) contains: erythromycin 100% (Ph.
Eur. ) 1200 mg of zinc acetate dihydrate micronized (Ph.
Eur. ) 360 mg.
Excipients:
Diisopropyl sebacate (monograph) 7.81 (8.36 ml), ethanol (Ph.
Eur. ) 17.1 (21.6 ml).
Description:
Packaging the drug vial is two, one of which contains the active substance in powder form, and the other – auxiliary components as a solution.
The final solution: a colorless transparent liquid.
Product form:
powder for solution for external application together with the solvent in vials of 30 ml, and an applicator into a cardboard package with instructions for use.
Contraindications
Hypersensitivity to erythromycin and other macrolides; increased sensitivity to zinc.
Indications
Acne treatment.
Interaction with other drugs
To date, no established clinically significant interactions zineritom with other drugs.
Overdose
Accidental overdose is unlikely due to the nature of the local application of the drug.
pharmachologic effect
Pharmacological group:
Acne treatment for rashes.
Pharmacodynamics:
Zener – Erythromycin-zinc complex.
It has anti-inflammatory, antimicrobial activity and komedonoliticheskoe action.
Erythromycin acts bacteriostatic against microorganisms that cause acne: Propionibacterium acne and Streptococcus epidermidis. Zinc reduces the production of sebum, astringent action.
Pharmacokinetics:
Integrated communication formulation components provides good skin penetration of active agents. Zinc is mainly associated with the follicular epithelium and is not resorbed into the systemic circulation. A minor part of the distribution system is exposed to erythromycin and subsequently excreted from the body.
Pregnancy and breast-feeding
It is now established that it is possible to use the drug during pregnancy and lactation (breast-feeding) according to indications in the recommended doses.
Conditions of supply of pharmacies
Without recipe.
side effects
Local reactions sometimes can occur burning sensation, irritation, dryness of the skin at the site of drug (as a rule, these conditions are mild and do not require discontinuation of therapy and / or symptomatic therapy).
special instructions
It should take into account the likelihood of developing perekresnoy resistance to other macrolides, lincomycin, clindamycin. It is necessary to avoid contamination of the eye, the mucosa of the mouth and nose (may result in irritation or burns).
Storage conditions
At a temperature of 15 to 25 C, the reach of children.
Dosing and Administration
Outwardly. Using the provided applicator Zinerit applied thinly to the affected area of ​​the skin 2 times per day: in the morning (before applying makeup) and evening (after washing). Apply the drug should by inclination of the vial with the prepared solution down with light pressure. The deposition rate of the solution is regulated pressing force of the applicator to the skin. Est single dose – 0.5 ml. After drying the solution becomes invisible.
Duration of the course – 10-12 weeks. In some cases it is possible clinical improvement after 2 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist