Termikon cream appearance. 1% 15g tuba

Description

Composition
Active substance:
1 g of cream contains: terbinafine hydrochloride – 10.0 mg.
Excipients:
Cetyl alcohol, stearyl alcohol or cetostearyl alcohol – 80.0 mg, benzyl alcohol – 10.0 mg, cetyl palmitate – 20.0 mg Polysorbate 60 – 61.0 mg, isopropyl myristate – 80.0 mg Sorbitan Stearate – 19.0 mg of sodium gidrokcid – 1.2 mg purified water – to 1000, 0 mg.
Description:
White homogeneous cream with low specific smell.
Product form:
Cream for external application of 1% in tubes of 10 g of aluminum or 15, one in a tube with instructions for use placed in a pile of cardboard.
Contraindications
Increased sensitivity to terbinafine or to any component of the formulation; breastfeeding; Children up to age 12 years (for a given dosage form).
Precautions: hepatic and / or renal failure, alcoholism, depression of bone marrow hematopoiesis, tumors, metabolic disease, limb occlusive vascular disease.
Dosage
1 %
Indications
Prevention and treatment of fungal skin infections, including: • the foot mycoses ( “mushroom” of the foot); • jock itch; • fungal infections smooth skin of the body; • infections caused by yeast fungi of the genus Candida (Candida), in particular diaper rash; • Motley (tinea) stripping.
Interaction with other drugs
Any drug interactions for Termikona® cream is not known.
Overdose
No cases of overdose have been reported. If accidentally Termikon® cream will be ingested, it is possible to expect development of the same side effects as an overdose of pills Termikona® (headache, nausea, epigastric pain and dizziness).
Treatment: activated charcoal, if necessary – symptomatic supportive therapy.
pharmachologic effect
Pharmacological group:
Antifungal agent.
Pharmacodynamics:
Antifungal agent for topical application, with a broad spectrum of antifungal activity. In nizkihkontsentratsiyah terbinafine has fungicidal activity against dermatophytes (Trychophyton rubrum, T. mentagrophytes, T. verrucosum, T. violaceum, T. tonsurans, Microsporum canis, Epidermophyton floccosum), molds (e.g., Aspergillus, Cladosporium, Scorpulariopsis brevicalius), certain dimorphic (Pityrosporum orbiculare) and yeasts (mainly Candida albicans). Activity against other yeast fungi Candida spp., Depending on their type, may be a fungicidal or fungistatic.
Terbinafine specifically alters the early stage of the biosynthesis of sterols, occurring in fungi. This leads to a deficiency of ergosterol and to an intracellular accumulation of squalene, which causes death of fungal cells. Action terbinafine accomplished by inhibition of the enzyme squalene epoxidase located on the cell membrane of the fungus.
Terbinafine has no effect on cytochrome P450 system in humans and, accordingly, the metabolism of hormones or other drugs.
Pharmacokinetics:
When applied topically absorption – less than 5% has little systemic effect.
Pregnancy and breast-feeding
teratogenic properties of terbinafine have been identified in experimental studies. To date, no reports of any malformation when applying cream terbinafine.
However, as clinical experience with terbinafine in the form of a cream in pregnant women is very limited, it should not be used unless absolutely necessary. When pregnancy is used only if the intended benefits to the mother outweighs the potential risk to the fetus. It is necessary to consult with your doctor.
Terbinafine is excreted in breast milk, so the drug should not be applied to nursing mothers. Do not allow contact with the baby any skin surface treated with cream.
Conditions of supply of pharmacies
Without recipe.
side effects
In the field application of the drug redness, itching or a burning sensation. Allergic reactions.
special instructions
Reducing the severity of the clinical manifestations usually noted in the first days of treatment. In the case of irregular or premature treatment termination there is a risk of renewed infection.
Termikon® Cream is for external use only. Avoid contact with eyes, as it may cause irritation. In case of accidental spraying into the eyes, they should immediately wash with running water, and in the case of persistent phenomena of irritation consult a doctor.
With the development of allergic reactions need to remove the drug.
Storage conditions
Store at a temperature not higher than 30 C. Keep out of reach of children.
Dosing and Administration
Outwardly.
Adults and children from 12 years: Before applying the cream to clean and dry the affected area. The cream is applied 1 or 2 times per day with a thin layer to the affected and surrounding skin areas and lightly rubbed. For infections involving intertrigo (under the breasts, interdigital spaces, between the buttocks, groin), lotions application site can be covered with gauze, especially at night.
The average duration and frequency of use:
Tinea pedis 1 week 1 time per day
Ringworm of the body, legs, folds, 1 week 1 time per day
Candidiasis-skin 1-2 weeks 1 or 2 times a day
Colorful lichen-2 weeks 1 or 2 times a day
Reducing the severity of the clinical manifestations usually noted in the first days of treatment. In the case of irregular or premature treatment termination there is a risk of renewed infection.
The dosage regimen of the drug in the elderly is not different from the above.
Use of the drug in children. We do not recommend the use of this drug in children under 12 years.
If after treatment there is no improvement or there are new symptoms, you should consult with your doctor.
Use drug only according to the application and in those doses which are specified in the instruction. If necessary, please consult your physician before using the drug.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist