Perhotal Ointment 2% 15g tuba

Description

Composition
Active substance:
100 g of ointment contains: ketoconazole 2.0 g
Excipients:
Macrogol 400, macrogol 4000.
Description:
Homogeneous ointment white.
Product form:
Ointment for external use 2%; 15 mg in a plastic tube with a plastic screw cap; 1 tube together with instructions for use in a cardboard box.
Contraindications
Ointment PERHOTAL not be used for high sensitivity to ketoconazole, by breakage of the skin in places intended application of ointment, for women during lactation.
Carefully
As a result of clinical trials ketoconazole in the plasma is not found, however, for women during pregnancy should be taken with caution.
Dosage
2%
Indications
Local treatment of mycosis caused by fungi sensitive to a drug: jock itch, athlete’s hands and feet, skin candidosis, pityriasis versicolor, seborrheic dermatitis caused by Pityrosporum ovale.
Interaction with other drugs
Drug interaction preparation is not described PERHOTAL when used topically.
Overdose
Because the drug is intended for external use only, and is practically not absorbed into the systemic circulation, the development of symptoms of an overdose unlikely. In case of accidental admission into ointments should undertake to carry out gastric lavage and symptomatic treatment.
pharmachologic effect
Pharmacological group:
Antifungal agent.
Pharmacodynamics:
Ketoconazole, imidazol-dioxolane derivative, has an antifungal activity against dermatophytes, such as Trichophyton sp., Epidermophyton sp., Microsporum sp., Yeasts, such as Candida sp., Dimorphic fungi, and eumitsetov Malassezia furfur (Pityrosporum ovale). The mechanism of action is the inhibition of ergosterol synthesis and membrane lipids (phospholipids and triglycerides) required for the synthesis of the cell wall of fungi (mushrooms lose their ability to form colonies and filament) and the violation cell wall permeability. Inhibits the transformation of Candida albicans blastospores into invasive forms. Ketoconazole exhibit antifungal activity against Pityrosporum ovale and Pityrosporum orbiculare, causing excessive scaling of the skin, it is also active against staphylococci and streptococci.
Pharmacokinetics:
Absorption of the active ingredient through the skin when applied topically significantly. Prolonged use of ketoconazole content is not detected in the blood.
Conditions of supply of pharmacies
Without recipe.
side effects
When applied topically, the ointment PERHOTAL possible local allergic reactions in the form of burning, skin rashes and urticaria. In rare cases, a contact dermatitis.
special instructions
The drug is intended for external use only, do not use in ophthalmic practice. Avoid contact with the eyes ointment.
When combined with long-term use by local dosage forms glucocorticosteroids (GCS) for preventing the syndrome of “cancel” it is recommended to use GKS morning and ointment PERHOTAL – night, followed by gradual withdrawal of corticosteroids within 2-3 weeks.
During treatment should follow the general rules of hygiene.
Information about the presence of any adverse effects from the missing children, efficacy and safety of the application they are not installed.
Storage conditions
At a temperature of not higher than 30 C.
In the reach of children.
Dosing and Administration
When skin tinea (athlete’s groin, hands and feet tinea, candidiasis of the skin and pityriasis versicolor) ointment applied to the affected and immediately adjacent thereto region 1 time per day.
In seborrheic dermatitis ointment applied to the affected area two times a day.
The average duration of treatment is:
When tinea skin – 3-4 weeks
When jock itch – 2-4 weeks
When athlete’s foot – 4-6 weeks
Infections caused by yeast fungi – 2-3 weeks
When pityriasis versicolor – 2-3 weeks
In seborrheic dermatitis – 2-4 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist