Nizoral 2% shampoo 120ml fl

Description

Composition
Active substance:
1 g of shampoo contains: ketoconazole 20 mg.
Excipients:
Sodium lauryl sulfate 380 mg, disodium lauryl sulfosuccinate 150 mg, diethanolamide of fatty acids of coconut oil 20 mg, collagen hydrolyzate, 10 mg, macrogol metildekstrozy dioleate 10 mg Sodium chloride 5 mg of hydrochloric acid, 4 mg, imidurea 2 mg flavor 2 mg hydroxide 1 Sodium mg dye “red-floors’ (E 129) 30 mg water to 1 g
Description:
Red-orange liquid.
Product form:
Shampoo 2%. 25, 60 or 120 ml of the drug vial of high density polyethylene with a screw cap. Each vial together with instructions for use in a cardboard box.
Contraindications
Known hypersensitivity to any component of the shampoo.
Dosage
20 mg / ml
Indications
Treatment and prevention of infections caused by the yeast Malassezia spp. (Pityrosporum spp.), Such as pityriasis versicolor (local), seborrheic dermatitis and dandruff.
Interaction with other drugs
Data on interaction with other drugs absent.
Overdose
When using shampoo NIZORAL®® 2% of overdose is not expected since the drug is intended for external use only. In case of accidental ingestion should be assigned symptomatic and supportive therapy. To prevent aspiration of vomit or prohibited use of gastric lavage.
pharmachologic effect
Pharmacological group:
Antifungal agent.
Pharmacodynamics:
Ketoconazole, a synthetic derivative of imidazole-dioxolane has an antifungal activity against dermatophytes, such as Trichophyton spp., Epidermophyton spp., Microsporum spp., And yeasts such as Candida spp. and Malassezia spp. (Pityrosporum spp.). Nizoral® Shampoo 2% rapidly decreases flaking and itching, which is usually accompanied by seborrheic dermatitis, dandruff, pityriasis versicolor.
Pharmacokinetics:
Concentration of ketoconazole is not determined in blood plasma after topical application Nizoral® shampoo 2% on the scalp, but determined after topical application to the whole body shampoo at a concentration of 11.2 ng / ml – 33.3 ng / ml. It is unlikely that these concentrations may cause any drug interactions, however, may enhance allergic reactions.
Pregnancy and breast-feeding
Controlled studies in pregnant and lactating women have not been conducted. There is no evidence that the drug NIZORAL® 2% shampoo can be dangerous when used in pregnant and lactating women.
Pregnancy and lactation are used only if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Conditions of supply of pharmacies
Without recipe.
side effects
According to clinical studies:
Adverse reactions observed at> 1% of patients after application NIZORAL® 2% shampoo to the scalp or skin is not revealed.
Adverse reactions observed in
From the side of view:
Eye irritation, increased lacrimation.
Systemic disorders and complications at the injection site: erythema at the site of application, application site irritation, hypersensitivity, pruritus, pustules, skin reactions.
Immune system: Hypersensitivity
Infections and infestations: folliculitis
From the nervous system: a violation of taste sensitivity on the part of the skin and subcutaneous tissue: acne, alopecia, contact dermatitis, dry skin, impaired hair texture, burning sensation, skin rash, skin exfoliation.
According to postmarketing studies:
Unwanted effects listed below according to the following classification:
Very often> 1/10
Often> 1/100, 1/1000 but but 1/10000, but
Violations of the skin and subcutaneous tissue:
Very rare: swelling, hives, change in hair color.
special instructions
When using the shampoo should avoid contact with eyes. After contact with shampoo in eyes wash them with water.
To prevent withdrawal prolonged topical treatment with corticosteroids is recommended to continue the topical application of corticosteroids in combination with 2% shampoo NIZORAL® followed by gradual withdrawal of corticosteroids within 2-3 weeks.
If the drug has come into disrepair or expiration date – do not pour it into the waste water and not be thrown into the street! Place the drug in the bag and place in the trash. These measures will help protect the environment!
Effects on ability to drive and operate machinery
NIZORAL® 2% shampoo does not affect the ability to drive and operate machinery.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
Children from infancy, adolescents and adults.
Apply to the affected area NIZORAL® 2% shampoo for 3-5 minutes, then rinsed with water.
Treatment: pityriasis versicolor: once daily for 5 days; seborrheic dermatitis and dandruff: twice a week for 2-4 weeks.
Prevention: pityriasis versicolor: once daily for 3 days (single treatment course before the onset of summer). seborrheic dermatitis and dandruff: 1 weekly or once every two weeks. Features use in children is not available.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist