Ksimelin eco menthol spray Nazal. scrapper. 140mkg / 10ml dose vials. with crucified.

Description

Composition
Active substance:
1 dose contains: 140 mg Xylometazoline hydrochloride.
Excipients:
Sorbitol 1.96 mg Hydrogenated castor oil 350 g 42 g levomenthol cineole (eucalyptol) 28 mg Sodium chloride 728 mg Sodium dihydrogen phosphate dihydrate 280 mg Sodium dihydrogenphosphate dihydrate 280 mg Disodium edetate 70 mg Purified water to 140 microliters.
Description:
Clear or slightly opalescent, colorless or lightly colored liquid with a characteristic odor.
Product form:
Nasal spray metered 140 ug / dose. 10 ml of the product (at least 60 doses) in a plastic bottle fitted with a dosing pump action device with a tip and a protective cap made of polyethylene. 1 bottle together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity to xylometazoline and other ingredients, hypertension, tachycardia, expressed atherosclerosis, glaucoma, sicca and atrophic rhinitis, hyperthyroidism, post transsphenoidal hypophysectomy, surgical interventions in the meninges (history), pregnancy, children up to 10 years. Do not use the drug in the therapy or monoamine oxidase inhibitors tricyclic antidepressants, including the period of 14 days after their withdrawal.
Carefully
Diabetes; pheochromocytoma; diseases of the cardiovascular system, including Coronary artery disease, angina III – IV functional class; porphyria; breastfeeding; prostatic hyperplasia; atherosclerosis; hypersensitivity to adrenergic drugs accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.
Dosage
140 micrograms / dose
Indications
Acute respiratory illness with symptoms of rhinitis (common cold), acute allergic rhinitis, hay fever, sinusitis, evstahiit, otitis media (to minimize swelling of nasal mucosa). Preparing the patient for diagnostic procedures in the nasal passages.
Interaction with other drugs
Application Xylometazoline contraindicated in patients receiving MAO inhibitors or tricyclic antidepressants, including the period of 14 days after their withdrawal. The simultaneous use of tri- or tetracyclic antidepressants and sympathomimetic drugs can lead to increased sympathomimetic effect of xylometazoline, however such combinations should be avoided.
Overdose
Xylometazoline local administration of excessive doses or accidental ingestion can cause severe dizziness, irregular pulse, sweating, a sharp decrease in body temperature, headache, bradycardia, hypertension, respiratory depression, coma and convulsions. Following the increase in blood pressure can be observed its sharp decline. Appropriate supportive measures should be taken in any suspected overdose. In some cases, symptomatic treatment is shown immediately under the supervision of a physician. These should include monitoring the patient for several hours. In case of severe poisoning with cardiac arrest CPR should be continued for at least 1 hour.
pharmachologic effect
Pharmacological group:
Mechanically vasoconstrictor decongestant (alpha-agonists).
Pharmacological properties:
Xylometazoline refers to a group of local vasoconstrictive agents (decongestants) with alpha-adrenomimeticheskim action causes vasoconstriction of nasal mucosa, thereby eliminating, mucosal swelling and nasal congestion. Xylometazoline also reduces concomitant hypersecretion of mucus and secretions facilitates drainage of blocked nasal passages, and thus improves nasal breathing when nasal congestion. At therapeutic concentrations does not irritate, does not cause flushing. Effect occurs within 2 minutes after application and lasts for 12 hours. In vitro studies have shown that ksilometazolin inhibit the infectious activity of the human rhinovirus, which causes “cold.”
Pharmacokinetics:
When applied topically, practically not absorbed, the plasma concentrations are so small that they can not identify with modern analytical methods.
Pregnancy and breast-feeding
Use of the drug is contraindicated in pregnancy. During breastfeeding the drug should only be used after careful assessment of risks and benefits for mother and child, under the supervision of a physician. It is not allowed to exceed the recommended dosage.
Conditions of supply of pharmacies
Without recipe.
side effects
The classification of the frequency of occurrence of adverse reactions: very often (> 1/10); common (> 1/100,
special instructions
Should not be used for a long time (more than 10 days). Long term (over 10 days) or excessive use may cause the effect of “rebound” (rhinitis medicamentosa) and / or atrophy of nasal mucosa. Do not exceed the recommended dose, especially in children and the elderly. If symptoms worsen or the patient’s condition does not improve within 3 days of application ksimelin Eco with menthol, it is necessary to consult a doctor.
The effect on the ability to operate a vehicle or equipment:
Ksimelin Eco Menthol does not affect the ability to drive a vehicle or equipment.
Storage conditions
At a temperature of not higher than 30 ° C.
Keep out of the reach of children.
Dosing and Administration
Intranasally. For adults and children over 10 years: 1 injection into each nasal passage (can be repeated if necessary); should not be used more than 3 times a day. Duration of treatment – no more than 10 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist