Galavit rectal suppositories 100mg 10 pieces

Description

Composition
Active substance:
1 suppository contains: Sodium aminodigidroftalazindion (Galavita) 100 mg or 50 mg.
Excipients:
Witepsol W-35 (fatty acid glycerides) – 575 mg Witepsol H-15 (fatty acid glycerides) – 575 mg.
Description:
Suppositories from white to white color with a yellowish shade, torpedo-shaped with no visible inclusions in longitudinal section.
Product form:
Suppositories 50 mg or 100 mg.
Packing 10 5 or suppositories.
Contraindications
Idiosyncrasy; Pregnancy and lactation.
Dosage
100 mg
Indications
As an immunomodulatory and anti-inflammatory agent in the treatment of immunodeficiency disorders in adults and adolescents over 12 years: infectious intestinal diseases accompanied by intoxication and / or diarrhea, gastric ulcer and 12 duodenal ulcer viral hepatitis chronic relapsing disease caused by the virus of the disease herpes, caused by a virus human papillomavirus infection-inflammatory urogenital diseases (urethritis Chlamydia and trichomoniasis etiology of prostate chlamydial um, acute and chronic oophoritis, endometritis) pyo-inflammatory diseases of the pelvic organs, postoperative rehabilitation of patients with uterine myoma postoperative complications in women of reproductive age purulent surgical diseases (burn injury, chronic osteomyelitis, gangrenous appendicitis with omentitom, peritonitis, purulent pleurisy) postoperative pyo-septic complications and their prevention (including cancer patients), chronic recurrent furunculosis, erysipelas Asten cal state, neurotic and somatoform disorders, decreased physical performance (including athletes); mental, behavioral and postabstinentnom disorders in alcohol and drug dependence inflammatory diseases of the oral mucosa and throat, periodontal disease frequent recurrent airway disease and ENT bacterial and viral etiology (frequent SARS, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) and their prevention.
Interaction with other drugs
With simultaneous application may decrease the dose courses of antibiotics. Cases of incompatibility is not observed with other drugs.
pharmachologic effect
Pharmacological group:
Immunomodulatory and anti-inflammatory agent.
Pharmacological properties:
The mechanism of action of the drug is associated with the ability to influence the functional and metabolic activity of macrophages.
In inflammatory diseases of the drug for 6-8 hours reversibly inhibits excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, reactive oxygen species giperaktivirovannymi macrophages, which determine the degree of inflammatory reactions, their recurrence, as well as the severity of intoxication. The normalization of the functional state of the macrophages leads to the restoration of antigen-presenting and regulating macrophage function, reduce the level of self-aggression. It stimulates the microbicidal activity of neutrophils, enhancing phagocytosis and increasing nonspecific resistance of the organism to infectious diseases.
Pharmacokinetics:
Excreted mainly by the kidney. After rectal administration half-life of 40-60 minutes. The main pharmacological effects are observed for 72 hours.
Conditions of supply of pharmacies
Without recipe.
side effects
In rare cases, allergic reactions are possible.
Storage conditions
Store at a temperature not higher than 25 C, protected from light, the reach of children.
Dosing and Administration
Rectally. Suppository free of contour packaging, and then introduced into the rectum. Pre-empty the bowels. Dose and duration of administration of the drug depends on the nature, severity and duration of the disease.
In acute infectious intestinal diseases accompanied by diarrhea syndrome: initial dose is 2 suppository once, followed by 1 suppository 2 times per day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course 1 suppository every 72 hours. Course 20-25 suppositories.
In gastric ulcer and duodenum 12 in the acute period: 2 days to 1 suppository 2 times a day, followed by 1 suppository every 72 hours. Course 15-25 suppositories. In chronic period: 5 days 1 suppository 1 time per day, then one at a time – 72 hours. The course of 20 suppositories.
In viral hepatitis: the initial dose is 2 suppository once, followed by one – 2 times a day until relief of symptoms of intoxication and inflammation. The subsequent continuation of the course 1 suppository every 72 hours. Course 20 -25 suppositories.
In chronic recurrent diseases caused by herpes virus: 1 suppository daily 5 suppositories, then one a day – 15 suppositories.
In diseases caused by papilloma virus: 5 days 1 suppository 1 time a day, then one suppository every other day. Course – 20 suppositories.
When urogenital diseases – chlamydia and trichomonas urethritis etiology, chlamydial prostatitis: 1 day 1 suppository twice, then one every other day. Rate 10-15 suppositories (depending on the severity of a pathological process).
When oophoritis, endometritis in the acute phase: 2 days to 1 suppository 2 times a day, then one by one every 72 hours. In chronic period: 5 days 1 suppository 1 time per day, then one by one every 72 hours. Course – 20 suppositories.
In acute and chronic septic diseases of the pelvic organs – in the acute period: 1 day 2 suppository once, 3 days one suppository daily, then one a day for 5 days. Course – 10 suppositories. In chronic period: 5 days 1 suppository 1 time per day, then one by one every 72 hours. Course – 20 suppositories.
For post-operative rehabilitation of patients with uterine myoma and postoperative complications in women of reproductive age: 5 days 1 suppository 1 time a day, and then one by one – in a day. Course – 15 suppositories.
For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients) appoint 1 suppository 1 time per day – 5 suppositories before surgery, 5 – after the operation at a time through the day and 5 suppository – c interval 72 hours. In severe disease initial dose 2 suppository once or 2 times per day by one. Course – 20 suppositories.
In chronic recurrent furunculosis, erysipelas: 5 days, one suppository 1 time a day, and then one by one – in a day. Course – 20 suppositories.
Asthenic states, neurotic and somatoform disorders, with mental, behavioral and postabstinent disorders in patients with alcohol and drug dependence: 5 days, one suppository daily, then one by one – in 72 hours. Course 15-20 suppositories. To improve the physical performance: 1 suppository every other day – 5 suppository, followed by one – after 72 hours, rate – 20 suppositories.
In inflammatory diseases of the mucous membranes of the mouth and throat, periodontal disease: initial dose 1 suppository daily – 5 suppository, followed by one – with an interval of 72 hours. The course of 15 suppositories.
For non-specific prevention and treatment of influenza and acute respiratory infections by one suppository 1 time per day. The course of 5 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist