Furadonin aveksima tab 100mg 20 pieces

Description

Composition
Active substance:
Nitrofurantoin monohydrate (furadonin) – 100 mg.
Excipients:
Potato starch – 46.15 mg Colloidal silicon dioxide – 2.00 mg stearic acid – 1.00 mg, polysorbate-80 (Tween-80) – 0.85 mg.
Description:
Tablets or yellow to greenish yellow color ploskotsilindricheskoy form chamfered, light allowed marbling on the surface.
Product form:
Tablets of 100 mg.
10 tablets in contour bezgyachakova packaging together with instructions for medical use.
At 10 or 20 tablets in blisters.
20 tablets in a glass jar for storage of medicines. 1, 2, 3, 4 or 5 contour cell packs of 10 tablets 1 contour cell pack 20 of tablets or bank 1 for 20 tablets, together with instructions for medical application is placed in a pile of cardboard.
Contraindications
Hypersensitivity, chronic renal failure, cardiac insufficiency II-III art., Liver cirrhosis, chronic hepatitis, deficiency of glucose-6-phosphate dehydrogenase, acute porphyria, pregnancy, lactation, children under 3 years.
Dosage
100 mg
Indications
Bacterial urinary tract infection (pyelitis, pyelonephritis, urethritis, cystitis), prevention of infections in urologic surgery or examination (cystoscopy, catheterization and the like).
Interaction with other drugs
The simultaneous use of nalidixic acid and an antacid comprising magnesium trisilicate, reduces antibacterial effect. Incompatibility with fluoroquinolones. Drugs that block tubular secretion, reduced antibacterial effect (by reducing the concentration of nitrofurantoin urine) and increase the toxicity (increased blood concentration) of the drug.
Overdose
Symptoms: vomiting.
Treatment: drinking large amounts of fluid leads to increased excretion of the drug in the urine. Effective dialysis.
pharmachologic effect
Pharmacological group:
Antimicrobials nitrofuran.
Pharmacodynamics:
The antimicrobial agent, a derivative of a group means nitrofurans, primarily for the treatment of urinary tract infections. Penalized protein synthesis in bacteria and the permeability of the cell membrane. Active against gram-positive and gram-negative bacteria (Staphylococcus spp., Streptococcus spp., Shigella dysenteria spp., Shigella flexneri spp., Shigella boydii spp., Shigella sonnei spp., Escherichia coli., Proteus spp.).
Pharmacokinetics:
Absorption from the gastrointestinal tract – good. Bioavailability – 50% (food increases bioavailability). The rate of absorption depends on the crystal size (microcrystalline form is characterized by rapid dissolution and absorption rate, shorter time to reach maximum concentration in the urine). Relationship to plasma proteins – 60%. It is metabolized in the liver and muscle. The half – 20-25 minutes. It crosses the placenta, the blood-brain barrier, excreted in breast milk. Completely displayed kidney (30-50% – unchanged).
Pregnancy and breast-feeding
Use of the drug during pregnancy and breast-feeding period is contraindicated.
Conditions of supply of pharmacies
On prescription.
side effects
Nausea, vomiting, allergic reactions (lupus-like syndrome, arthralgia, myalgia, anaphylaxis, fever, rash,), dizziness, headache, fatigue, nystagmus, drowsiness, interstitial changes in the lungs, bronchial obstruction, fever, cough, chest pain , hepatitis, cholestatic syndrome, peripheral neuropathy, pancreatitis, pseudomembranous enterocolitis, rare – abdominal pain, diarrhea.
special instructions
During the period of treatment must be careful when driving and busy with other potentially hazardous activities that require high concentration and psychomotor speed reactions (with the appearance of dizziness and sleepiness).
Storage conditions
Store in a dark place at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside, drinking plenty of water, adults – 0.1-0.15 g, 3-4 times a day; children – a rate of 5-8 mg / kg / day, the daily dose divided into 4 doses. Higher doses for adults: single – 0.3 g daily – 0.6 g
In acute urinary tract infection the duration of treatment – 7-10 days. Prophylactic, antirecurrent treatment continues, depending on the nature of the disease, from 3 to 12 months.
The daily dose in this case is 1-2 mg / kg.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist