Erythromycin ointment 10000ed / g 15g tuba

Description

Composition
Active substance:
1 g of ointment contains: erythromycin (in terms of active ingredient) – 10 thousand.
ED.
Excipients:
Lanolin Anhydrous – 0.4 g sodium disulfite (sodium metabisulfite, sodium pyrosulfite) – 0.0001 g, to 1 g Petrolatum
Product form:
Ointment for external application 10 thousand.
U / g. 5 g, 10 g, 15 g aluminum tubes or tube laminate. Each tube with instructions for use placed in a pile of cardboard.
Contraindications
Individual hypersensitivity.
Dosage
10,000 units
Indications
skin and soft tissue infections (pustular skin diseases, including common acne, infected wounds, decubitus ulcers, burns II-III art., trophic ulcers).
Interaction with other drugs
The drug is incompatible with lincomycin, clindamycin, chloramphenicol (antagonism). It reduces the bactericidal activity of beta-lactam antibiotics (penicillins, cephalosporins, carbapenems). With simultaneous application of erythromycin dosage forms for external use with abrasive materials, resulting in excessive skin irritation, as well as to drugs which cause peeling of the skin, irritating or possible cumulative drying effect.
Overdose
Data on overdose of the drug available.
pharmachologic effect
Pharmacological group:
Antibiotic – macrolide.
Pharmacological properties:
Bacteriostatic macrolide antibiotic. When applied topically has antibacterial and anti-acne effect. Reversibly binds to the 50S subunit of the ribosome, which disrupts the formation of peptide bonds between the molecules of amino acids, and blocks the synthesis of proteins of microorganisms (does not affect the synthesis of nucleic acids). When used in high doses, depending on the type of agent may exhibit bactericidal activity. The spectrum of action includes Gram-positive (Staphylococcus spp., Streptococcus spp., Bacillus anthracis, Corynebacterium diphtheriae) and Gram negative (Neisseria gonorrhoeae, Haemophilus influenzae, Bordetella pertussis, Brucella spp., Legionella spp.) Microorganisms, as well as Mycoplasma spp., Chlamidia spp. , Treponema spp., Rickettsia spp. To a drug resistant Gram negative bacillus Escherichia coli, Pseudomonas aeruginosa, and Shigella spp., Bacteroides fragilis, Enterobacter spp. And etc.
Pregnancy and breast-feeding
Not indicated.
Conditions of supply of pharmacies
On prescription.
side effects
May develop allergic reactions and irritating (redness, itching). With prolonged use may develop a secondary infection caused by microorganisms resistant to erythromycin.
special instructions
Prior to the use of any other anti-acne medicament for topical use should be at least 1 hour. If within 3-4 weeks acne condition does not improve, should consult a physician (to achieve a full therapeutic effect requires 2-3 months. With prolonged use possible development of superinfection.
Storage conditions
At temperatures above 25 ° C. Keep out of the reach of children.
Dosing and Administration
Outer: ointment applied to the affected skin 2-3 times a day, duration of treatment – 1.5-2 months. Purulent diseases of skin and soft tissues of the ointment applied to the affected skin area with a thin layer of 1-2 times a day after removal of pus and necrotic masses, burns – 2-3 times a week.
The duration of treatment depends on the type and severity of the disease and varies from a few days to 2 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist