Ekofuril caps. 200mg 16 pieces

Description

Composition
Active substance:
Nifuroxazide 200.0 mg.
Excipients:
Microcrystalline Cellulose – 58.0 mg potato starch – 18.0 mg Magnesium stearate – 6.0 mg, sucrose to obtain a mass of the capsule contents 630.0 mg. Hard gelatin capsules №00: [gelatin (100%), water (14-15%) Lid: dye Ponceau [Ponceau 4R] (0,079801%), patent blue dye (0.00165%), dye sunset (0.093301%), titanium dioxide (0.813158%); Housing: quinoline yellow dye (0.583356%) colorant sunset (0.002565%), titanium dioxide (0.974035%)].
Description:
Capsules № housing 00 with yellow and orange cover.
Product form:
Packing 16 pcs.
Contraindications
Hypersensitivity to nifuroxazide, other ingredients, other derivatives of 5-nitrofuran. Deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption.
Children up to age 3 years (for this lekform).
Dosage
200 mg
Indications
Acute and chronic diarrhea infectious origin (without any signs of helminthic infestations).
Chronic colitis and enterocolitis.
Overdose
Specific symptoms of an overdose is not described. Recommended standard first aid measures.
pharmachologic effect
Pharmacological group:
The antimicrobial agent – nitrofuran.
ATC code: A07AH03.
Pharmacological properties:
Antimicrobial broad-spectrum – derivative 5-nitrofuran. Used to treat infections of the gastrointestinal tract. Nifuroxazide blocks dehydrogenase activity and inhibits the respiratory chain cycle of tricarboxylic acids and other biochemical reactions in a bacterial cell. Destroys the membranes of sensitive bacteria, it reduces the production of toxins by microorganisms. Activates the immune system, increases the activity of phagocytes and complement titer.
It is effective against Gram-positive microorganisms: Staphylococcus spp; Streptococcus spp..
Gram-negative microorganisms Salmonella spp;. Klebsiella spp;. Enterobacter spp;. Escherichia coli; Shigella spp;. Proteus spp;. Haemophilus influenzae; Campilobacter spp;. Edwarsiella spp;. Citrobacter spp;. Vibrio cholerae; Yersinia enterocolitica.
Nifuroxazide no effect on the state of the normal microflora of the human gut. In acute bacterial diarrhea restoring intestinal eubioz. When infected by viruses enterotropnymi prevents the development of bacterial superinfection.
Pharmacokinetics:
After oral administration nifuroxazide practically not absorbed in the gastrointestinal tract and has no systemic action. Antibacterial activity against susceptible bacteria manifests only in the intestinal lumen. The unchanged output of the intestines. elimination rate is dependent on the dose and the motility of the gastrointestinal tract.
Pregnancy and breast-feeding
There are no data regarding the adverse effects on the fetus during pregnancy. If necessary, with caution, the drug can be administered to pregnant and breastfeeding women.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions.
special instructions
In the treatment of diarrhea in conjunction with therapy nifuroxazide necessary to conduct rehydration therapy (oral or intravenous) in accordance with the condition of the patient and duration of diarrhea.
During therapy nifuroxazide not allowed alcohol intake.
The effect on the ability to drive and carry out work requiring high concentration and psychomotor speed reactions.
The drug has no negative impact on the ability to drive and / or other mechanisms.
Storage conditions
In dry and dark place at a temperature not higher than 25 ° C. Keep out of the reach of children.
Dosing and Administration
Adults and children older than 7 years of age: 1 capsule 4 times a day (800 mg / day).
Children 3 – 7 years of age: 1 capsule 3 times a day (600 mg / day).
Duration of therapy nifuroxazide – not more than 7 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist