Diara tab Gesves. 2mg 12 pcs Obolensky

Description

Composition
Active substance:
1 tablet contains: loperamide hydrochloride 2 mg ;.
Excipients:
Polymethylsiloxane, potato starch, lactose (milk sugar), sucrose (sugar), microcrystalline cellulose, colloidal silicon dioxide (Aerosil), aspartame, povidone (Kollidon 90), xylitol (Xylitab 300), lactitol, Kollidon SR, menthol, magnesium stearate, anise oil.
Description:
Tablets white or white color with a yellowish shade, ploskotsilindricheskoy shape with Valium, anise odor. Slight “marbling”.
Product form:
Chewable tablets.
4, 6, 7 or 10 tablets in blisters of PVC film and aluminum foil printed patent.
1, 2 or 3 blisters with instructions for use placed in a pile of cardboard.
Contraindications
Hypersensitivity to the drug, diverticulosis, intestinal obstruction, ulcerative colitis in the acute stage, acute diarrhea with pseudomembranous enterocolitis, as monotherapy – dysentery and other infections of the gastrointestinal tract; pregnancy (I trimester), lactation, children’s age (up to 6 years).
Carefully
Liver failure.
Dosage
2 mg
Indications
Symptomatic treatment of acute and chronic diarrhea of ​​various origins (allergic, emotional, drug, radiation, with a change in diet and qualitative composition of food, in violation of metabolism and absorption, and as an adjunct in the diarrhea of ​​infectious origin).
Regulation of stool in patients with iliostoma.
Overdose
Symptoms: inhibition of central nervous system (CNS) (stupor, incoordination, drowsiness, cramps, muscle hypertonia, respiratory depression), intestinal obstruction.
Treatment: antidote – naloxone; Considering that the duration of action of loperamide is greater than that of naloxone, may re-introduction of the latter.
Symptomatic treatment: activated charcoal, gastric lavage, artificial lung ventilation (ALV). Necessary medical supervision, at least for 48 hours.
pharmachologic effect
Pharmacological group:
Antidiarrheals.
Pharmacodynamics:
Loperamide by binding with opioid receptors of the intestinal wall (modulation of cholinergic neurons and adrenergic through guanine nucleotide), reduces the tone and motility of the intestinal smooth muscles (by inhibiting the release of acetylcholine and Pg).
Slows peristalsis and increases the passage of intestinal contents. It increases anal sphincter tone, helps keep feces and deceleration urge to defecate. The action comes fast and lasts 4-6 hours.
Pharmacokinetics:
Almost completely metabolized by the liver by conjugation. T1 / 2 (half-life) -. 9-14 hours is derived mainly from the kidney and gall (as conjugated metabolites).
Conditions of supply of pharmacies
Without recipe.
side effects
Gastralgia, dry mouth, allergic reactions (rash), drowsiness, dizziness, intestinal colic, nausea, vomiting, and constipation. Very seldom – intestinal obstruction.
special instructions
If no effect within 48 hours use of the preparation should be discontinued and seek medical advice.
Storage conditions
In a dry, dark place at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside, liquid, squeezed water. Adults with acute and chronic diarrhea administered in an initial dose of 2 tablets (4 mg); then – 1 tablet (2 mg) after each act of defecation (in the case of watery stools); maximum daily dose – 8 tablets (16 mg).
In acute diarrhea children over 6 years administered in an initial dose of 2 mg followed by 2 mg after each act of defecation (in the case of watery stools); maximum daily dose – 3 tablets (6 mg).
By normalizing stool or chair in the absence of more than 12 hours of treatment should cease diarrhea.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist