Corvalol herbal drops for ext. applying 50ml fl.v ind.up. Pharmstandard

Description

Composition
Active substance:
motherwort herb tincture – 720.00 mg; etylbromisovalerianate – 20.00 mg; peppermint leaf oil (peppermint oil) -1.42 mg.
Excipients:
Purified water – up to 1 ml.
For 100 ml of tincture of Leonurus 20 g used motherwort herb and a sufficient amount of ethyl alcohol 70%.
Description:
Transparent liquid greenish-brown color with a characteristic smell. Presence of a slurry of small particles. During storage, allowed the formation of a precipitate.
Product form:
Drops for oral administration.
50 ml vial (dropper bottle) of glass dropper-capped plugs, with screw-caps.
The bottle (bottle-IV), together with instructions for use placed in a pile of cardboard.
Contraindications
– increased sensitivity to the drug;
– severe renal dysfunction and / or liver;
– erosive and ulcerative lesions of the gastrointestinal tract (acute phase);
– pregnancy;
– the period of breast-feeding;
– Children up to age 18 years (effectiveness and safety have been established).
Precautions – Disturbances of liver and / or kidney;
– Epilepsy;
– Alcoholism;
– Patients at high risk, including those with liver disease, brain injuries, brain diseases.
If you have one of these diseases / conditions before taking this medication, you should consult with your doctor.
Indications
Sleep disorders, neurosis state accompanied by increased irritability and excitability, excitation states with pronounced vegetative manifestations; as an antispasmodic – with cramps, as well as symptomatic (sedative and vasodilator) means in functional disorders of the cardiovascular system.
Interaction with other drugs
With simultaneous application of medicament Corvalol Phyto with drugs depressing the central nervous system (sedatives, hypnotics, neuroleptics, tranquilizers) may mutual enhancing effects. It enhances the effect of antispasmodic, analgesic agents. Alcohol enhances the effect of the drug and its toxicity.
Overdose
Overdosing is possible with frequent and prolonged use of the drug. When exceeding the recommended dose may be increased dose-related side effects.
Symptoms: weakness, drowsiness, dizziness. With prolonged use may be a manifestation of chronic intoxication with bromine (See. Side effect profile).
Treatment: symptomatic.
pharmachologic effect
Pharmacological group:
sedative.
Pharmacodynamics:
A combined preparation, which effect is due to the properties of the substances contained in it. Has sedative and antispasmodic action, cardiotonic action moderate (slow rhythm and increases the strength of cardiac contractions) has a moderate antihypertensive properties.
Etylbromisovalerianate has sedative and antispasmodic action due to stimulation, preferably oral cavity and nasopharynx receptor, decrease reflex excitability in the central parts of the nervous system and the deceleration gain in neurons of the cortex and subcortical brain structures and decreased activity of central vasomotor centers and direct local spasmolytic action on smooth muscles.
motherwort herb has a strong sedative (sedative), mild cardiotonic (rhythm slows and increases the strength of heart contraction) effect, moderate hypotensive effect.
Peppermint oil has vasodilating reflex, skin, lung choleretic, antiseptic action. The mechanism of action is related to the ability to irritate “Cold» receptors oral mucosa and reflexively extend predominantly vessels of the heart and brain. Eliminates meteorism due to irritation receptors mucosa of the gastrointestinal tract (GIT), increasing intestinal motility.
Pharmacokinetics:
Data on the pharmacokinetics etylbromisovalerianate, motherwort components and peppermint no mint.
Pregnancy and breast-feeding
Security korvalola Phyto during pregnancy has not been established and its use is contraindicated in this period. These components of the penetration of the drug into breast milk is not available, so if necessary, use during lactation should decide the issue of termination of breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Immune system: allergic reactions;
Central nervous system: drowsiness, weakness, dizziness, decreased ability to concentrate;
Cardio-vascular system: slow heart beat;
On the part of the gastrointestinal tract: dyspepsia.
These phenomena take place at lower dose or discontinuation of the drug. With prolonged use of high doses of the drug may develop drug dependence, as well as the accumulation of bromine in the body and development of the phenomena bromism, manifestations of which are: depressed mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements.
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
The experience of the drug in children under 18 years of age, during pregnancy and breastfeeding is not available. Not recommended for prolonged use of the drug in high doses, in connection with a possible toxic effect when cumulation bromine in the body. During the use of the drug should not drink alcohol.
Phyto Corvalol contains 47.5% ethyl alcohol, so when administered in a single dose maximum drug content of absolute ethyl alcohol (ethanol) was 0.308 g, to the maximum daily dose – 0.923 g
Effect on the ability to drive mechanisms and
Due to the possibility of dizziness, poor concentration, and other side effects associated with taking the drug during the treatment period, patients are advised to refrain from car driving lessons and other potentially hazardous activities that require high concentration and psychomotor speed and motor responses.
Storage conditions
Store at a temperature not higher than 25 degrees.
Keep out of the reach of children.
Dosing and Administration
adults
Taken orally before meals, three times a day on 30 drops, previously dissolved in a small amount (30-40 ml) of water.
The course of treatment 4 weeks (28 days). The duration of intake can be increased by the doctor’s recommendation.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist