Zovirax cream naruzhn.prim I-5% 5 g tube


Zovirax cream naruzhn.prim I-5% 5 g tube



Active substance:
Acyclovir 5,00 g
Poloxamer 407 1.00 g, 6.75 g cetostearyl alcohol, white soft paraffin 11.50 g sodium lauryl sulfate 0.75 g 5.00 g liquid paraffin, glycerol monostearate, 0.75 g, macrogol stearate 0.75 g 40.00 g of propylene glycol, dimethicone 1.00 g purified water to 100.00 g
Uniform cream white or nearly white, without small, large and foreign particles, with no signs of separation.
Product form:
Cream for external use 5%.
5 g of product in an aluminum tube with screw cap plastic / aluminum tube or plastic bottle placed in a cardboard box, together with instructions for use.
Increased sensitivity to acyclovir, valaciclovir, propylene glycol or other components of the formulation.
5 %
The treatment of viral infections caused by the virus Herpes simplex, lips and skin (recurrent labial herpes).
Interaction with other drugs
When applied topically interaction with other drugs is not revealed.
Because of the minimal systemic exposure is not expected occurrence of undesirable effects when administered topically or all contents consumer packaging Zovirax cream. Should consult a doctor if you suspect an overdose.
pharmachologic effect
Pharmacological group:
An antiviral agent.
Acyclovir – antiviral – in vitro is highly active against the virus Herpes simplex (HSV) types 1 and 2. Low toxicity to host cells – a mammal. Once in the cells infected with the herpes virus, acyclovir is phosphorylated to the active acyclovir triphosphate compound. The first step of this process depends on the presence of HSV – encoded thymidine kinase enzyme. Acyclovir triphosphate acts as an inhibitor and substrate herpes – specific DNA polymerase, inhibiting further synthesis of viral DNA, thus, without affecting the normal cellular processes.
Pharmacological studies have shown minimal systemic absorption by repeated application of acyclovir cream.
Pregnancy and breast-feeding
Application is possible only in cases where the expected benefit outweighs the potential risk and the unknown, but the systemic exposure in the local application of a cream is very low.
As a result, post-marketing experience with acyclovir were derived data comprising information on the outcome of pregnancy in women who received drug Zovirax in any dosage form. The data do not show an increase in the number of congenital malformations among patients treated with acyclovir in comparison to the general population, and have been recorded birth defects that would constitute a unique and characterized by a constant set of signs that point to a common cause.
Prior to use if you are pregnant or suspect that you might be pregnant, or planning to become pregnant, during breast-feeding should consult a doctor.
Limited data show that regular use of the drug passes into breast milk. However, the dosage received by a baby who is breastfed is negligible.
Conditions of supply of pharmacies
Without a prescription.
side effects
Side effects are classified according to organ system and frequency. The frequency of side effects is defined as follows: very often> 1/10, often> 1/100 and 1/1000 and 1/10000 and
Skin and subcutaneous tissue disorders
Infrequently – transient burning, tingling at the application site of the drug, or small dry desquamation, itch;
Rarely – redness; contact dermatitis after application, often associated with response to adjuvants than acyclovir.
Violations by the immune system
Very rarely – hypersensitivity reactions of immediate type, including angioedema, urticaria.
If you have marked side effects indicated in the instructions or they are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
Zovirax cream for external use should be applied only in case of skin herpes lips and face. Not recommended for use on the mucous membranes of the mouth, eye and vagina. Do not use to treat genital herpes. Avoid getting the cream in the face.
When expressed manifestations of recurrent herpes are advised to consult with a physician.
Patients with herpes of the lips to avoid transmission of the virus, especially in the presence of active lesions.
Patients with compromised immune systems are not recommended for use Zovirax cream for external use. Such patients in the treatment of any infectious disease should follow the doctor’s recommendations.
Patients with renal and hepatic impairment:
Despite the fact that most of acyclovir excreted by the kidneys, systemic absorption of acyclovir after topical application is negligible. Accordingly, there is no need to change the dose in patients with kidney or liver disorders.
Effect on the ability to drive mechanisms and
The drug Zovirax does not affect the ability to drive vehicles or to engage in other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
Store at a temperature not higher than 25 ° C. Do not freeze. Keep out of the reach of children.
Dosing and Administration
For external use only.
Use according to the drug only indications that the application and in those doses which are specified in the instruction.
Adults and children:
The drug is recommended to be applied 5 times a day, about every 4 hours, except for the night-time and bordering the affected skin with them. It is important as soon as possible it is desirable to begin treatment at the first signs and symptoms (as prodromal or reddening). The treatment may also start at a later stage (papule or bladder).
The duration of treatment not less than four days. In the absence of healing, treatment may be continued up to 10 days. In the case of preservation of symptoms more than 10 days, you should consult a doctor.
To prevent deterioration and to prevent the spread of infection, it is necessary to wash their hands before and after drug application without rubbing or touching the affected areas of the skin with a towel.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg

GlaxoSmithKline Helsker

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