Xylene asset Nazal Spray. 0.1 ml of 15%

Description

Composition
Active substance:
1 ml contains: Xylometazoline hydrochloride 1.0 mg.
Excipients:
Sodium dihydrogen phosphate dihydrate 2.0 mg sodium hydrogen phosphate dodecahydrate 2.8 mg sodium chloride 5.0 mg benzalkonium chloride 0.05 mg sorbitol (70% solution) 14.0 mg Disodium edetate dihydrate 0.5 mg, levomenthol (menthol) 0.3 mg, cineole (eucalyptol) 0.2 mg macrogol glitserilgidroksistearat (Cremophor RH 40) 2.5 mg purified water to 1.0 ml.
Description:
Colorless transparent liquid with an odor of menthol and eucalyptus.
Product form:
Nasal Spray, 0.1%.
10 g, 15 g or 20 g of polymer bottles of high density polyethylene for nasal spray with a spray device and a protective cover screwed with the first control opening. 1 vial together with instructions for use in a pile of cardboard.
Contraindications
Increased sensitivity to the drug, hypertension, tachycardia, expressed atherosclerosis, glaucoma, atrophic rhinitis, fructose intolerance, surgical interventions in the meninges (history), the state after transsphenoidal hypophysectomy, pregnancy, children under 6 years.
Do not use in the treatment of monoamine oxidase inhibitors and tricyclic antidepressants, including the period of 14 days after their withdrawal.
Carefully
Diabetes, prostatic hyperplasia, hyperthyroidism, porphyria, breastfeeding, diseases of the circulatory system, including ischemic heart disease, pheochromocytoma, patients with hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.
Dosage
1 mg / ml
Indications
Acute respiratory illness with symptoms of rhinitis (common cold), acute allergic rhinitis, hay fever, sinusitis, evstahiit, otitis media (to reduce nasopharyngeal mucosa edema), preparation of the patient for diagnostic manipulations in the nasal passages.
Interaction with other drugs
Not compatible with monoamine oxidase inhibitors and tricyclic antidepressants.
Overdose
In case of overdose or accidentally taking the drug inside may develop the following symptoms: dizziness, increased sweating, sudden drop in body temperature, headache, bradycardia, hypertension, respiratory depression, coma and convulsions. Following the increase in blood pressure can be observed its sharp decline.
Treatment: symptomatic. Observation of the patient for several hours. In case of severe poisoning with cardiac arrest CPR should be continued for at least 1 hour.
pharmachologic effect
Pharmacological group:
Decongestant agent – alpha-agonists.
Pharmacodynamics:
Alpha-agonists to cause vasoconstriction of nasal mucosa, eliminating mucosal swelling and nasal congestion. Relieves nasal breathing in rhinitis.
Xylene asset well tolerated by patients with sensitive mucosa of the nasal cavity, as the drug has a balanced pH, typical of the nasal cavity. Contained in the formulation menthol and eucalyptol have a cooling effect on the nasal mucosa, giving a feeling of freshness.
At therapeutic concentrations do not irritate the nasal mucosa, does not cause flushing. Pharmacological action occurs within a few minutes and lasts for several hours.
Pharmacokinetics:
When applied topically, practically not absorbed, the plasma concentrations are so small that they can not identify with modern analytical methods.
Pregnancy and breast-feeding
During pregnancy, the use of the drug is contraindicated.
During breastfeeding the drug should only be used after careful assessment of risks and benefits to both mother and baby, is not allowed to exceed the recommended dosage.
Conditions of supply of pharmacies
Without recipe.
side effects
Classification of the incidence of adverse reactions: very common (> 1/10), common (> 1/100 –
special instructions
Not recommended for use in a continuous mode for more than 7 days, as with a longer use may develop the symptoms of nasal congestion. Prolonged use of or exceeding the recommended doses may lead to reactive hyperemia nasal mucosa, nasal breathing difficulty and rhinitis medicamentosa and / or atrophy of the mucosa of the nasal cavity.
Effects on ability to drive and use other mechanisms
The drug does not affect the ability to drive vehicles or equipment. With prolonged use exceeding the recommended doses can not exclude the possibility of systemic effects. In such cases, caution should be exercised when driving or operating equipment.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
Intranasally.
Adults and children over 6 years: 1 injection in each nostril, 3 times a day; should not be used more than 3 times per day.
Duration of treatment – no more than 7 days without consulting a doctor. During the administration of the drug vial should be kept up spray, and after the injection is recommended for easy inhale nose.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist