Vikasol injection 1% 1ml amp 10 pcs

Description

Composition
Active substance:
1 ml of solution contains: menadione sodium bisulfite (Vikasol) based on menadione sodium bisulfite trihydrate – 10.0 mg ;.
Product form:
A solution for intramuscular injection of 10 mg / ml.
Contraindications
Increased sensitivity to the drug. Increased blood clotting, thrombosis. Hemolytic disease of the newborn. Pregnancy and lactation.
Precautions: deficiency of glucose-6-phosphate dehydrogenase, liver failure.
Dosage
1 %
Indications
Hemorrhagic syndrome associated with gipoprotrombinemiey; hypovitaminosis K (including the obstructive jaundice, hepatitis, cirrhosis, prolonged diarrhea); bleeding after injuries, injuries and surgical interventions; in the complex therapy of dysfunctional uterine bleeding, menorrhagia. Treatment and prevention of hemorrhagic disease of the newborn. Overdose preparations of vitamin K-antagonists (warfarin, phenindione, acenocoumarol).
pharmachologic effect
Pharmacological group:
Vitamin K is a synthetic analogue. ATC code V02VA02.
Pharmacological properties:
The water-soluble analogue of vitamin K (vitamin K3), promotes the synthesis of prothrombin and proconvertin, increases blood coagulation by enhancing the synthesis of II, VII, IX, X clotting factors. Has hemostatic action (when vitamin K deficiency arises increased bleeding). In the blood, prothrombin (factor II) in the presence of thromboplastin and calcium ions, the participation proconvertin (Factor VII), IX factors (Kristmass factor), X (factor Stewart-Prauera) passes into thrombin, under the influence of which the fibrinogen is converted to fibrin constituting the blood clot (thrombus). Substrate stimulates vitamin K-reductase, activating vitamin K and ensures its participation in the hepatic synthesis of K-vitaminzavisimyh plasma hemostasis factors. Starting effect – after 8-24 hours (after intramuscular injection).
Conditions of supply of pharmacies
Prescription.
Dosing and Administration
The drug is administered intramuscularly. For adults, a single dose of 10-15 mg, the maximum single dose – 30 mg, with a maximum daily dose – 60 mg. In pediatrics: newborn to 4 mg / day to 1 year, 2-5 mg / day of 1-2, 6 mg / day of 3-4, 8 mg / day of 5-9 years 10 mg / day 10-14 years 15 mg / day From the age of 15 is assigned to the drug as well as adult patients. Duration of treatment 3-4 days, after a four-day break, repeated for 3-4 days. The daily dosage may be divided into 2-3 doses. When the possible surgical interventions bleeding parenchymal strong administered for 2-3 days before surgery.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist