Tsefekon Mr. rectal suppositories 10 pc

Description

Composition
Active substance:
1 suppository contains caffeine – 50 mg, naproxen – 75 mg, salicylamide – 600 mg ;.
Excipients:
Hard fat (Witepsol, brand H 15, W 35, Supposir, grade NA 15, NAS 50) – to obtain a suppository weighing 2.20 g
Description:
Suppositories are white or white with yellowish or Valium a color shade, torpedo-shaped. On the longitudinal section of the suppository should be no blotches, tolerance of air core or funnel-shaped depressions.
Product form:
Rectal suppositories. 5 suppositories in blisters. Two blisters with instruction for medical use of the formulation was put in a cardboard box.
Contraindications
Hypersensitivity to the drug, gastric ulcer and duodenal ulcers (acute phase), complete or partial combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid or the like. NSAIDs (including history), hypocoagulation, heavy renal and / or hepatic insufficiency, hypertension, organic diseases of the cardiovascular system, heart failure, blood disorders, edema, the pathology of the vestibular apparatus, higher constant prices irritability, insomnia, angle-closure glaucoma, children’s age (16 years), pregnancy, lactation.
Indications
As an analgesic for pain syndrome, mild to moderate: neuralgia, myalgia, sciatica, lumbago; degenerative and dystrophic diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, ankylosing spondylitis); headache, toothache, migraine; dysmenorrhea (painful menstruation); as antipyretic agents: catarrhal febrile syndrome, infectious diseases, inflammatory diseases.
Interaction with other drugs
Naproxen reduces the hypotensive effects of beta-blockers. With simultaneous use of naproxen may cause a decrease diuretic effects of furosemide. Naproxen increases the toxicity of phenytoin, sulfonamides, methotrexate.
Salicylamide enhances the effect of anticoagulants, antiplatelet agents, fibrinolytics. Salicylamide increases the risk of side effects of glucocorticoids, mineralokortikosteroidov, estrogen, when used together. When applied simultaneously with salicylamide myelotoxicity drugs increases the risk of inhibition of brain blood circulation (hematopoiesis).
Caffeine speeds up the absorption and enhances the action of cardiac glycosides and increases their toxicity. The combined use of caffeine with beta-blockers may lead to mutual suppression therapeutic effects; with adrenergic bronchodilators drugs – for extra stimulation of the central nervous system and other additive toxic effects..
Overdose
No cases of drug overdose Tsefekon® H were reported.
pharmachologic effect
Pharmacological group:
Combined analgesic (NSAID + psychostimulant agent).
Pharmacological properties:
Tsefekon® H – Combined drug has analgesic, antipyretic and anti-inflammatory effect.
Naproxen and salicylamide are nonsteroidal anti-inflammatory drugs (NSAIDs), the mechanism of action of which is associated with the inhibition of prostaglandin synthesis and effects on the thermoregulatory center in the hypothalamus.
Caffeine has a psychostimulant, analeptic and antispasmodic effect on smooth muscle.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions, dizziness, excitation, drowsiness, psychomotor slowing reactions, tinnitus, tachycardia, increased blood pressure, anemia, agranulocytosis, aplastic anemia, liver dysfunction and / or kidney; itching and pain in the rectum.
special instructions
When the itching or discomfort in the rectum need to stop using the product and seek medical advice.
During treatment, you should be careful when driving and occupation of other potentially hazardous activities that require high concentration of attention, psychomotor speed of reaction and good vision.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Rectally. Suppository free from blisters and after spontaneous bowel cleansing enema or enter deeply into the rectum 1 suppository 1-3 times a day. After introduction of the suppository must stay in a horizontal position for 30-40 minutes.
The duration of intake without consultation with a physician is not more than 5 days when administered as an analgesic and 3 days as an antipyretic.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist