Trombless gel appearance. 1000me / g 30g

Description

Composition
Active substance:
Heparin sodium – 1,000 IU (0.00833 g sodium heparin on activity 120 IU / mg) ;.
Excipients:
Ethanol (ethyl alcohol) – 0.24 g methyl parahydroxybenzoate (Nipagin, methylparaben) – 0.0012 g propyl parahydroxybenzoate (Nipasol, propylparaben) – 0.0003 g, diethanolamine (2,2-iminodiethanol) – up to obtain 0.014 g of gel to pH 7.5 to 8.7, carbomer (carbopol) – to 0.015 g of water (purified water) – up to 1 g
Description:
The gel is colorless or with a slight yellowish tint, transparent, with a specific smell.
Product form:
Gel for external use 1000 IU / g. For 30g tubes in aluminum or plastic laminated tubes. Each tube together with instructions for medical use of the formulation was put in a pile of cardboard.
Contraindications
Hypersensitivity to the drug. Necrotizing, purulent processes in the skin; traumatic breach of integrity of the skin; increased tendency to bleeding, thrombocytopenia.
Indications
Thrombophlebitis of superficial veins; localized edema and infiltration of soft tissues; subcutaneous bruising (including hematoma after phlebectomy), trauma and injuries of joints, tendons, muscle tissue.
Interaction with other drugs
The combined use of a gel with indirect anticoagulants can cause elongation of prothrombin time. The gel was not administered topically concurrently with non-steroidal anti-inflammatory drugs, tetracyclines, antihistamine drugs.
Overdose
Due to the low systemic absorption overdose unlikely.
pharmachologic effect
Pharmacological group:
Anticoagulant means of direct action for topical application.
Pharmacodynamics:
Direct anticoagulant, anti-inflammatory, antiproliferative, anti-inflammatory and analgesic effects. Decreases platelet aggregation binds antithrombin III, preventing the passage of prothrombin to thrombin. Depresses the activity of thrombin. It reduces the activity of hyaluronidase, increases fibrinolytic properties of blood. Trombless® improves microcirculation activate tissue metabolism and, thereby accelerates the resorption of haematomas and blood clots, eventually restores patency veins, clinically it is accompanied by a pronounced analgesic and antiinflammatory action.
Pharmacokinetics:
Minor amounts of heparin absorbed from the skin into the systemic circulation. The maximum concentration of drug in the blood observed after 8 hours after application. Excretion of heparin occurs mainly via the kidney, half-life 12 hours.
Pregnancy and breast-feeding
Perhaps the use of the drug during pregnancy and lactation if the potential benefit to the mother outweighs the risk to the fetus and child.
Conditions of supply of pharmacies
Without recipe.
side effects
Prolonged use of the drug possible local reactions in the form of redness of the skin, allergic reactions.
special instructions
The drug should not be used for bleeding, as well as on open wounds, mucous membranes and purulent processes.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Outwardly. Gel Column length 10.3 cm light rubbing movements applied to the skin above the affected portion 1-3 times a day. The gel is used daily, an average of from 3 to 7 days. Duration of treatment is determined by the doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist