Troksimetatsin gel naruzhn.prim th 40g


Troksimetatsin gel naruzhn.prim th 40g


SKU: 0314234689 Categories: , , Tags: ,


Active substance:
1 g of gel contains: indomethacin – 30 mg, troxerutin – 20 mg ;.
Carbomer – 15 mg Disodium edetate – 0.5 mg Sodium benzoate – 2.5 mg Macrogol 400 – 522 mg, 150 mg izopropanol-, dimethyl – 150 mg Purified water – 110 mg.
Uniform transparent gel from yellow to yellow-brown color.
Product form:
Gel for external application. 40 g aluminum tubes with an internal lacquer coating, lithographic outer surface of the membrane and the sealing ring, with a polyethylene screw cap. Each tube together with instructions for use placed into cardboard pack.
Hypersensitivity to the drug; hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs); III trimester of pregnancy and lactation; Children up to age 14 years (due to lack of clinical use experience); violation of the integrity of the skin.
Precautions: simultaneous application of the drug to other NSAIDs, bronchial asthma, allergic rhinitis, nasal polyps mucosa.
For the symptomatic treatment: in the treatment of chronic venous insufficiency of the lower extremities (varicose veins) to relieve swelling, feelings of heaviness and pain in the legs; superficial thrombophlebitis, phlebitis; postflebitnye state; rheumatic soft tissue: tendonitis, bursitis, fibrositis, periarthritis; postoperative swelling, contusions, dislocations, sprains.
Interaction with other drugs
The gel may exacerbate the effects of drugs that cause photosensitization. Clinically significant interactions with other drugs has not been described.
There is no information about overdose when applied topically. In case of accidental ingestion of large amounts of the drug may burning sensation in the mouth, salivation, nausea, vomiting.
Treatment: washing the mouth and stomach, if necessary – symptomatic treatment.
pharmachologic effect
Pharmacological group:
Anti-inflammatory agent for topical application.
Combination preparation for topical application, which comprises indomethacin and troxerutin
Indomethacin has a pronounced anti-inflammatory, analgesic and anti-edematous action, leading to the removal of pain, reduction of edema and to reduce the recovery time of the affected tissues. The main mechanism of action is related to the suppression of prostaglandin synthesis by reversible blockade of cyclooxygenase 1 and 2.
Troxerutin (trigidroksietilrutinozid) is a bioflavonoid. It has angioprotective action. It reduces the permeability of capillaries and shows venotoniziruyuschee action. Venodilatiruyuschee blocks the action of histamine, bradykinin and acetylcholine. Okolovenoznuyu anti-inflammatory effect on the fabric, reduces capillary fragility and possesses some antiplatelet action. Reduces puffiness, improves trophism in various pathological changes associated with venous insufficiency.
Troksimetatsin gel when applied to skin edematous suppresses inflammatory reaction, reduces pain and temperature in the foci of inflammation, which are on the surface and in depth reaching the blood vessels located therein. It has expressed venous, kapillyaroprotektornoy action.
Usable gel base allows the solubility and the release of drug components Indomethacin and Troxerutin. The gel dosage form, which includes indomethacin and troxerutin, well absorbed from the skin and provides a therapeutic effect of the drug. When applied to the skin in the subcutaneous tissue and periarticular tissues are concentrations close to therapeutic. The penetration of the active ingredients in the systemic circulation is clinically insignificant.
Pregnancy and breast-feeding
Clinical experience, proving the safety of the drug when used during pregnancy and lactation is not available. Use of the drug is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or baby ^.
Conditions of supply of pharmacies
Without recipe.
side effects
Tolerability is usually very good.
Local reactions:
May cause hypersensitivity symptoms of the skin – contact dermatitis, itching, redness, rash, sensation of heat and burning at the application site.
special instructions
The preparation should be applied only to undamaged skin, to avoid contact with the eyes and mucous membranes. After applying the drug should not impose an occlusive bandage. In case of contact with eyes, mucous membranes or open wound surface observed local irritation – lacrimation, redness, burning, and pain. Corrective action in this case – washing the affected area with copious amounts of distilled water or physiological saline prior to reduction or disappearance of complaints. Sodium benzoate and dimethyl sulfoxide contained in the formulation as adjuvants may have an irritating effect on the skin.
The effect on the ability to operate vehicles, machinery
The drug has no effect on the ability to perform potentially hazardous activities that require high concentration and speed of psychomotor reactions (including the management of vehicles, work with moving machinery).
Storage conditions
At a temperature of not higher than 25 C.
Keep out of the reach of children!.
Dosing and Administration
The gel is applied topically. 3-4 times a day by rubbing a thin layer of gel into the skin of painful areas of the body. The amount required for one rubbing is about 4-5 cm of the gel squeezed from a tube. The total daily amount should not exceed 20 cm gel. The duration of treatment should not exceed 10 days.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg


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