Trimetazidine mV Table n / a film about prolong. 35mg 60 pcs ozone


Trimetazidine mV Table n / a film about prolong. 35mg 60 pcs ozone



Active substance:
1 tablet contains: trimetazidine dihydrochloride – 35 mg ;.
Product form:
35 mg of 10,20,30,60 tablets together with instructions for use placed in a cardboard box.
• Hypersensitivity to any component of the drug; • severe renal failure (creatinine clearance (CC) of less than 30 ml / min); • the age of 18 years (effectiveness and safety have been established); • pregnancy and lactation; • Parkinson’s disease, parkinsonism, tremor, a syndrome of “restless legs” and other related movement disorders.
35 mg
Ischemic heart disease: prevention of attacks of stable angina (as adjuvant therapy).
pharmachologic effect
Pharmacological group:
Antihypoxanth means.
Pharmacological properties:
It provides anti-hypoxic action. Directly affecting the cardiomyocytes and neurons in the brain, the drug to optimize their metabolism and function. Cytoprotective effect is due to an increase in potential energy, the activation of the oxidative decarboxylation and the rationalization of oxygen consumption (increased glycolysis and fatty acid oxidation blockade). Trimetazidine supports myocardial contractility, prevents the decrease in intracellular adenosine triphosphate (ATP) and phosphocreatine. In acidosis conditions normalize the functioning of ionic channels membranes, prevents the accumulation of sodium and calcium ions in cardiomyocytes normalizes the intracellular content of potassium ions. Reduces intracellular acidosis and increased phosphate content, due to myocardial ischemia and reperfusion. Prevents the damaging action of free radicals, preserves the integrity of cellular membranes, prevents activation of neutrophils in the ischemic area, increases the electrical potential, reduces yield creatine kinase (CK) cells and the severity of ischemic myocardial injury. Trimetazidine reduces the frequency of angina attacks, reduce the need for taking nitrates, after 2 weeks of treatment improves exercise capacity, reduced blood pressure sharp fluctuations (BP).
Conditions of supply of pharmacies
special instructions
Trimetazidine does not affect the ability to drive a car and perform work requiring a high rate of psychomotor reactions.
Dosing and Administration
Inside, during a meal. Trimetazidine MB appoint 1 tablet 2 times a day (morning and evening). In patients with moderate renal impairment (creatinine clearance of 30 to 60 ml / min), the drug is prescribed 1 tablet per day at breakfast. Elderly patients trimetazidine exposure may be increased due to age-related decline in kidney function. It is recommended to take 1 tablet 1 time per day. The advantage of therapy should be evaluated after 3 months, in the absence of effect of therapy should be discontinued.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg

OZONE generics

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