Trimedat tab 100mg 10 pieces

$11.31

Trimedat tab 100mg 10 pieces

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Description

Composition
Active substance:
1 tablet comprises: trimebutine maleate 100 mg or 200 mg ;.
Excipients:
Lactose, colloidal silicon dioxide, talc, corn starch, magnesium stearate.
Description:
Tablets white ploskotsilindricheskie symbol embossed on one side, which is a two letters TM, top and bottom of which are arranged in line on the three triangles and two intersecting risks on the other side tablets (for 100 mg dosage).
Tablets white round, biconvex embossed symbol on one side in the form of two elements and droplet line on the other side (for the 200 mg dosage).
Product form:
Tablets of 100 mg, 200 mg.
10 tablets in blisters of PVC film and aluminum foil printed patent.
1, 2 or 3 blisters together with instructions for use placed in a pile of cardboard boxed.
Contraindications
Hypersensitivity to the components included in the preparation.
Children under 3 years – for this dosage form.
Dosage
100 mg
Indications
Motor disorders in functional diseases of the gastrointestinal tract, gastroesophageal reflux disease, dyspepsia with gastroduodenal disorders (abdominal pain, dyspepsia, nausea, vomiting), irritable bowel syndrome (functional disorder of the gastrointestinal tract, which manifests itself, in particular, pain and abdominal cramps, spasms of the intestine, flatulence, diarrhea and / or constipation).
Postoperative paralytic ileus, preparation for radiological and endoscopic examination of the gastrointestinal tract.
Use in children: diarrheal disorders associated with impaired motility of the gastrointestinal tract.
Interaction with other drugs
Drug interaction Trimedat® preparation is not described.
Overdose
So far, cases of drug overdose Trimedat® were reported.
pharmachologic effect
Pharmacological group:
Antispasmodic.
Pharmacodynamics:
Trimebutine, acting enkefalinergicheskuyu bowel system, it is a regulator of motility. With affinity receptor stimulation and suppression, has a stimulating effect in states hypokinetic intestinal smooth muscle spasmolytic and – at hyperkinetic. The drug acts throughout the gastrointestinal tract, reduces the pressure of the sphincter of the esophagus, promotes gastric emptying and increase intestinal motility, as well as contributes to the response of smooth muscles of the colon to food stimuli. Trimebutin restores the normal physiological activity of the muscles of the intestine in various diseases of the gastrointestinal tract associated with impaired motor skills.
Pharmacokinetics:
After ingestion trimebutine is rapidly absorbed from the gastrointestinal tract, maximum plasma concentration (Cmax) is reached after 1-2 hours. Bioavailability is 4-6%. The volume of distribution (Vd) – 88 l. The degree of binding to plasma proteins is low – about 5%. Trimebutine slightly penetrates the placental barrier.
Metabolism and excretion:
Trimebutine biotransformed in the liver and excreted in the urine primarily as metabolites (approximately 70% during the first 24 hours).
Popuvyvedeniya period (T1 / 2) – about 12 hours.
Pregnancy and breast-feeding
Do not use the drug in the I trimester of pregnancy.
Do not appoint Trimedat® lactation, due to the lack of reliable clinical data supporting the safety of the drug during this period.
In experimental studies revealed no data on the teratogenicity and embryo toxicity of the drug.
Conditions of supply of pharmacies
Without recipe.
side effects
Rare: skin reactions.
special instructions
The course of treatment of irritable bowel syndrome in the acute period of 600 mg a day for 4 weeks and continued after the course of treatment in a dose of 300mg a day for 12 weeks, to avoid recurrence.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside. Adults and children from 12 years: 100-200 mg 3 times a day. To prevent recurrence of irritable bowel syndrome after the course of treatment in remission is recommended to continue taking the drug at a dose of 300 mg per day for 12 weeks. Children H-5 years: 25 mg W times a day. Children 5-12 years: 50 mg per day Zrazy.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Valenta Pharm

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