Triazavirin caps. 250mg 20 pieces

Description

Composition
Active substance:
Sodium dihydrate (Triazavirin) – 250 mg.
Excipients:
Calcium stearate – 2 mg
Capsule fill Mass – 252 mg
Composition Capsule shell:
The capsule (body) № 1: titanium dioxide (E171), quinoline yellow (E104), yellow “sunset” (E110), gelatin medical.
The capsule (cap) № 1: titanium dioxide (E171), azorubin (E122), gelatin medical.
Weight of capsule contents – 328 mg.
Description:
Hard gelatin capsule size № 1, the housing cap and yellow red color. Contents of capsules – crystalline powder or granules yellow or yellow-green.
Product form:
20 or 50 capsules in amber glass jars or cans polymer. Each jar together with instructions for use placed in a box made of cardboard.
10 capsules in blisters. 2 or 5, the contour of cellular packaging together with instructions for use placed in a pile of cardboard.
Contraindications
– increased sensitivity to the drug; – pregnancy; – the period of breast-feeding; – Children up to age 18 years (effectiveness and safety have defined); – renal / hepatic insufficiency (effectiveness and safety have defined).
Dosage
250 mg
Indications
Treatment of influenza in adults. If necessary, in Combination with symptomatic drugs.
Interaction with other drugs
Interaction with analogues of purine and pyrimidine bases during anticancer therapy can result in increased drug toxicity. While the use of ribavirin requires reduced doses of ribavirin.
Overdose
Symptoms include nausea, vomiting, dyspepsia, stomach pain.
Treatment: symptomatic therapy. When you see these symptoms should stop taking the drug.
pharmachologic effect
Pharmacological group:
An antiviral agent.
Pharmacodynamics:
Active substance formulation Triazavirin® – a synthetic purine nucleoside analogue bases (guanine) with a pronounced antiviral effect. It has a broad spectrum antiviral activity against RNA viruses.
Pharmacokinetics:
After intake of rapidly absorbed from the gastrointestinal tract. The maximum concentration (Cmax) is reached after an average of 1-1.5 hours. Cmax at the recommended dosing regimen is an average of 4.8 ug / ml. The magnitude of AUC (area under the curve “concentration – time”) of blood is 12.8 ug / ml * h. The half-life (T1 / 2) – 1-1,5 hours.
Kidneys in unchanged output of 15 to 45% of the formulation. The average value of the calculated clearance is 246 ml / min.
Pregnancy and breast-feeding
Use of the drug during pregnancy has not been studied.
Use of the drug during lactation has not been studied, therefore, if necessary, use during lactation should stop breastfeeding.
Conditions of supply of pharmacies
On prescription.
side effects
– allergies; – on the part of the digestive system: dyspeptic disorders (flatulence, diarrhea, nausea, vomiting).
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
Effects on ability to drive vehicles, machinery.
It has not been studied.
Storage conditions
In dry protected from light at a temperature not higher than 25 ° C.
The drug should be stored out of the reach of children.
Dosing and Administration
Triazavirin® applied orally without food.
therapeutic doses
The drug must begin no later than the 2nd day of onset (the appearance of clinical symptoms) 1 capsule (250 mg) 3 times a day (daily dose – 750 mg) for 5 days. If necessary, the treatment can be extended to 7 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist