Teraflex capsules for joint pain, 60 pcs., Bayer

$32.25

Teraflex capsules for joint pain, 60 pcs., Bayer

5 in stock

Quantity:

Description

Composition
Active substance:
1 capsule contains: 500 mg of glucosamine hydrochloride, chondroitin sulfate sodium 400 mg.
Excipients:
Stearic acid, magnesium stearate, manganese sulfate.
The gelatin capsule: gelatin.
Description:
Transparent hard gelatine capsules № 00. The contents of capsules – white or white powder with a yellowish shade with crystalline particles.
Product form:
Capsules 500 mg + 400 mg. 30, 60, 100 or 120 capsules were placed in a bottle of high-density polyethylene screw cap of the same material.
200 capsules were placed in a bottle of high-density polyethylene with a colored screw cap made of polypropylene with an overlay of a thermoplastic elastomer with a company logo.
Per vial membrane adhered composite material: aluminum foil / paper laminated with polyethylene. Cover and seal the neck of the vial transparent film. Each vial together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity, severe chronic renal failure, pregnancy, lactation, age under 15 years.
Dosage
500 mg plus 400 IU
Indications
Degenerative-dystrophic diseases of joints and spine: osteoarthritis I – III stage, low back pain.
Interaction with other drugs
It improves the absorption of tetracycline, reduces the effect of semi-synthetic penicillin and chloramphenicol. The product is compatible with NSAIDs and corticosteroids.
There is limited information on the possible interaction between glucosamine and warfarin, which may lead to increased risk of bleeding and INR. Therefore, while taking blood clotting parameters should be monitored.
Overdose
Symptoms of overdose cases is unknown. In overdose chondroitin sulfate possible haemorrhagic rash, nausea, vomiting. Treatment: gastric lavage, symptomatic therapy.
pharmachologic effect
Pharmacological group:
Tissue repair promoter.
Pharmacological properties:
Stimulates the regeneration of cartilage tissue. Glucosamine and chondroitin sulfate are involved in the synthesis of connective tissue, helping to prevent cartilage destruction processes and stimulating tissue regeneration. Exogenous glucosamine increases the production of cartilage matrix and provide non-specific protection against chemical damage to the cartilage. Another possible action of glucosamine is the protection of the damaged cartilage from metabolic destruction caused by nonsteroidal antiinflammatory drugs (NSAIDs) and glucocorticosteroids (GCS) and own a moderate anti-inflammatory effect.
Chondroitin sulfate is an additional substrate for the formation of healthy cartilage matrix. Stimulates formation gialuronona synthesis of proteoglycans and collagen type II, but also protects it from enzymatic cleavage gialuronon (by inhibition of hyaluronidase activity); It maintains the viscosity of synovial fluid, stimulates cartilage repair mechanisms and suppresses the activity of those enzymes that cleave cartilage (elastase, hyaluronidase). It facilitates the treatment of osteoarthritis symptoms of the disease and reduce the need for NSAIDs.
Pharmacokinetics:
glucosamine:
Absorption. The bioavailability of glucosamine orally at reception – 25% (the effect of “first pass” through the liver).
Metabolism. After absorption of the oral dose radiolabeled glucosamine initially detected in the plasma and later penetrates the tissue. The highest concentrations found in the liver, kidney, and articular cartilage. About 30% of the dose long persist in the bone tissue and muscles.
Elimination. Excreted mainly by the kidneys in unchanged form; partially – through the intestine. The half-life is 68 hours.
Chondroitin sulfate:
Absorption. When administered chondroitin sulfate once in a dose of 0.8 g of (or two times a day 0.4 g) plasma concentration is increased over 24 h. The absolute bioavailability is 12%.
Metabolism. It metabolized by desulfurization.
Elimination. Excreted by the kidneys. The half-life 310 minutes.
Pregnancy and breast-feeding
Clinical data on the efficacy and safety of the drug Terafleks® during pregnancy and lactation (breastfeeding) are absent.
Conditions of supply of pharmacies
Without recipe.
side effects
Terafleks® well tolerated by patients. Possible dysfunction of the gastrointestinal tract (epigastric pain, bloating, diarrhea, constipation), dizziness, headache, leg pain and peripheral edema, lethargy, insomnia, tachycardia, and allergic reactions.
special instructions
When the unwanted effects from the gastrointestinal dose should be reduced by 2 times, in the absence of improvement – to cancel the drug.
Storage conditions
At a temperature above 25 degrees Celsius.
Keep out of the reach of children.
Dosing and Administration
Inside. Adults and children over 15 years, the first three weeks, appoint 1 capsule 3 times a day; in the following days – 1 capsule 2 times a day, regardless of the meal, washed down with a little water. course recommended duration of treatment is 3 to 6 months. If necessary, may repeat courses of treatment, the duration of which is determined individually.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Teraflex

There are no reviews yet.

Add your review