Tamoxifen 20mg tabs 30 pcs ozone

$3.37

Tamoxifen 20mg tabs 30 pcs ozone

Quantity:

SKU: 01737477050 Categories: , Tags: ,

Description

Composition
Active substance:
1 tablet contains: tamoxifen citrate 15.2 mg or 30.4 mg per tamoxifen – 10 mg and 20 mg, respectively.
Product form:
Tablets of 10 mg and 20 mg. 10, 30 tablets in blisters of PVC film and aluminum foil printed patent. 10, 20, 30, 40, 50 or 100 tablets per plastic jars for medicaments. One jar or 1, 2, 3, 4, 5 or 10 contour cell packages together with instructions for use placed in a cardboard box (pack).
Contraindications
Increased sensitivity to tamoxifen and / or any other component of the preparation, pregnancy and lactation. Children’s age (data on efficacy and safety are no children).
Dosage
20 mg
Indications
breast cancer with estrogen-receptor positive early adjuvant cancer therapy. Treatment of locally advanced or metastatic breast cancer with estrogen-receptor positive. Breast cancer (including men after castration). Tamoxifen can also be used in other solid tumors, refractory to standard treatments, in the presence of overexpression of estrogen receptors.
pharmachologic effect
Pharmacological group:
The antitumor agent (antiestrogen).
Pharmacodynamics:
Tamoxifen is a nonsteroidal antiestrogen agent having as weak estrogenic properties. Its action is based on the ability to block estrogen receptors. Tamoxifen, as well as some of its metabolites compete with estradiol for binding sites with cytoplasmic estrogen receptors in tissues of the breast, uterus, vagina, the anterior pituitary gland and tumors with a high content of estrogen receptors. In contrast, the estrogen receptor complex receptor complex tamoxifen does not stimulate the synthesis of DNA in the nucleus and inhibits cell division that leads to the regression of tumor cells resulting in their death.
Pharmacokinetics:
If ingestion is well absorbed tamoxifen. The maximum serum concentration is achieved in the range of 4 to 7 hours after receiving a single dose. The equilibrium concentration of tamoxifen in serum is usually achieved after 3-4 weeks of treatment. Relationship to plasma proteins – 99%. Metaboliziruet- camping in the liver to form several metabolites isozyme is involved in the metabolism of CYP2C9. Tamoxifen excretion from the body has a biphasic pattern with an initial half-life of 7 to 14 hours and followed by a slow terminal elimination half-life for 7 days. Derived predominantly through the intestine, mainly as metabolites; insignificant amount – the kidneys.
Conditions of supply of pharmacies
Prescription.
Dosing and Administration
The inside is not liquid, squeezed small amounts of liquid in one go in the morning or by sharing the required dose into two doses (morning and evening). The dosage regimen is generally determined individually depending on the evidence. The daily dose is 20-40 mg. As a standard dose is recommended intake of 20 mg of tamoxifen daily inwardly long. If signs of progression reception cancel preparation disease.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

OZONE generics

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