Sulgin aveksima tab 500mg 10 pieces

Description

Composition
Active substance:
1 tablet contains: sulfaguanidine monohydrate (sulgina) – 500 mg. ;.
Excipients:
Potato starch – 96 mg Calcium stearate – 4 mg.
Description:
Tablets of white color, Valium with a facet and Valium.
Product form:
Tablets of 500 mg.
10 tablets in contour bezgyachakova packing or contour cell package.
1, 2, 3, 4 or 5, the contour of cellular packages with instructions for medical application is placed in a pile of cardboard. Outlined Valium packaging with an equal amount of instructions for medical use or pack made of cardboard is placed in multipacks.
Contraindications
Hypersensitivity to the drug or to other sulfonamides, lack of glucose-6-phosphate dehydrogenase, nefrourolitiaz, porphyria, B12-deficiency anemia, pregnancy, lactation, children under 3 years old, hyperbilirubinemia (in children).
Indications
Shigellosis; colitis and enterocolitis; preparation for surgery on the colon.
Interaction with other drugs
Reduces the reliability of oral contraceptives. Benzocaine, procaine reduced antimicrobial activity (upon hydrolysis release PABA). Nonsteroidal anti-inflammatory drugs, hypoglycemic drugs (sulfonylurea derivatives), phenytoin and indirect anticoagulants increase the severity of side effects of the drug. Ascorbic acid, hexamethylenetetramine increase the risk of crystalluria. Myelotoxic drugs increase the expression gematotoksichnosti drug.
Overdose
Data on overdose are not available.
pharmachologic effect
Pharmacological group:
The antimicrobial agent – sulfanilamide.
Pharmacodynamics:
Antimicrobial bacteriostatic agent. The mechanism of action is due to antagonism with para-aminobenzoic acid (PABA) and competitive inhibition digidropteroatsintetazy, which disrupts the synthesis of tetrahydrofolic acid required for the synthesis of purines and pyrimidines. Inhibits the growth of Escherichia coli and reduces the synthesis of thiamin, riboflavin, nicotinic acid in the intestine. Sulgin has a bacteriostatic effect on Streptococcus spp., Staphylococcus spp., Escherichia coli, Shigella dysenteriae, Proteus vulgaris.
Pharmacokinetics:
After oral drug slightly absorbed from digestive tract, whereby there is a high bacteriostatic concentration in the intestine.
Conditions of supply of pharmacies
On prescription.
side effects
From the digestive system: nausea, vomiting.
From the urinary system: crystalluria.
Allergic reactions: urticaria, exfoliative dermatitis.
Other: In hypovitaminosis, leukopenia, neuritis.
special instructions
In order to prevent crystalluria during the treatment period, patients should receive excessive drinking (2-3 liters / day). Early discontinuation of treatment or insufficient dose may result in the emergence of resistant strains of pathogens. During treatment, it is recommended intake of vitamins of group B.
Storage conditions
In a dry place at a temperature not higher than 30 ° C. Keep out of the reach of children.
Dosing and Administration
In acute dysentery spend 2 courses of treatment. The first course: 1 and Day 2 – 1g every 4 hours (total of 6 g / day), 3 and 4 day – 1g every 6 hours (4g / day), 5 and 6 day – 1 g every 8 hours ( 3 g / d). If necessary, after 5-6 days for the second course: 1 and Day 2 – 1g every 4 hours during the night – after 8 hours (total 5 g / day), day 3 and 4 – 1 g in 4 hours (4 g / d) do not give the night, 5 day – 3 g / day.
Children older than 3 years – 0.5 g 4 times a day for 7 days. In the treatment of other infections: adults – inside, 1-2 g every 4-6 hours; in the next 2-3 days – half dose.
Children older than 3 years – the first day to 0.1 g / kg / day in equal doses every 4 hours, on the following days – 0,25-0,5 g every 6-8 hours.
To prevent postoperative complications from intestinal – 0.05 g / kg every 8 h for 5 days before and 7 days after surgery.
Higher doses for adults: single – 2 grams daily – 7 g
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist