Sulfargin ointment 50g tube

Description

Composition
Active substance:
silver sulfadiazine – 10 mg;
Excipients:
Liquid paraffin – 230 mg; propylene glycol – 100 mg; cetostearyl alcohol – 60 mg; Glyceryl monostearate 40-55 – 30 mg; polysorbate 80 – 20 mg; methyl parahydroxybenzoate – 0.80 mg; propyl parahydroxybenzoate – 0.20 mg; Purified water – up to 1 year
Description:
Ointments white or nearly white, with a characteristic odor.
Product form:
Ointment for external application of 1%.
50 g (Manufacturer AO Tallinn pharmaceutical factory) or 50 g (for a producer “Grindeks”) in a tube of aluminum with an inner surface coated with a varnish with a protective aluminum membrane of the neck and the cone-shaped device to puncture the membrane is screwed Bouchon plastic . The tube together with instructions for use placed in a pile of cardboard boxed.
Contraindications
Pregnancy, lactation, children under 1 year; pronounced deficiency of glucose-6-phosphate dehydrogenase, and hypersensitivity to sulfonamide drugs.
The drug should not be used to treat deep purulent wounds and burns surfaces with plentiful exudation.
Carefully
Renal / hepatic failure, deficiency of glucose-6-phosphate dehydrogenase deficiency (risk of hemolysis).
In the case of the above diseases preparation before use is necessary to consult with a physician.
Indications
Treatment of the infected superficial wounds and burns surfaces with slight exudation, bedsores, grazes, skin ulcers, skin transplanted sites; as well as the prevention of infection.
Interaction with other drugs
sulfadiazine silver ointment The active ingredient can inactivate the enzyme preparations used for wound cleansing, so simultaneous use of these drugs is not desirable.
Overdose
Prolonged treatment of extensive burns surfaces sulfonamides can achieve the same values ​​of the plasma concentration as in the systemic treatment that defines overdose symptoms: nausea, abnormal liver function, crystalluria, renal failure, leukopenia. Treatment is symptomatic.
pharmachologic effect
Pharmacological group:
The antimicrobial agent, sulfanilamide.
Pharmacodynamics:
Sulfadiazine – antibacterial broad spectrum bactericidal action, referring to the group of sulfonamides. The drug is active against Gram-positive and Gram-negative bacteria Escherichia coli, Proteus spp., Staphylococcus spp., Klebsiella spp.
Bactericidal ointments properties due to the activity of silver ions that are released into the wound as a result of dissociation of the silver salt of sulfadiazine; release of silver ions is gradually (moderate dissociation), ensuring constancy antimicrobial effect. The bactericidal activity of the silver ions is supplemented by bacteriostatic effect of sulfadiazine (also liberated during dissociation silver salt of sulfadiazine).
The preparation is characterized by mild osmotic activity and has no necrolytic properties.
Pharmacokinetics:
When applied to the wound surface into the peripheral blood system and absorbed about 10% and 1% sulfadiazine silver. Applying to extensive wound surface accompanied by an increase in the blood concentration of sulfadiazine 10-20 ug / ml.
Pregnancy and breast-feeding
Do not use this drug during pregnancy and lactation.
Conditions of supply of pharmacies
Without a prescription.
side effects
The frequency of adverse reactions are classified according to the recommendations of the World Health Organization: very common (> 1/10), common (> 1/100,
special instructions
In the treatment of patients with hepatic and / or renal insufficiency must be regularly tested sulfonamides plasma concentrations.
Silver salts, reacting with air oxygen, metals and others. Chemical components, especially when catalyzes thermal exposure, darken, and the drug should be stored in a closed container away from heat sources.
Parts of the body treated with the drug, it is recommended to protect from direct sunlight.
In applying the drug should avoid contact with eyes.
The effect on the ability to operate vehicles, machinery
The drug does not affect the ability to drive and engage in other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
Ointment tubes stored at temperatures no higher than 25 ° C.
Do not freeze.
Ointment in sealed cans stored protected from light at a temperature not higher than 25 ° C.
Do not freeze.
Keep out of the reach of children.
Dosing and Administration
Outwardly. After debridement of necrotic tissue and remove the damaged surface is applied a thin layer (2-4 mm) ointment (sub band or open) 1-2 times a day.
The application on the skin is painless ointment, ointment does not stain clothes and underwear.
The maximum single dose – 300 g The treatment period is individual and depends on the nature of the disease and the effectiveness of the treatment applied in general cases lasts for up to 3 weeks.
If you forgot to apply the drug
If you forgot to apply the medication, use it as soon as possible and continue to use as normal. Do not use a double dose if the previous time the drug has been overlooked.
While maintaining the symptoms of the disease or aggravation of symptoms while taking the drug, you should inform your doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist