Sorbifer durules tab n / about 50 pc

$11.54

Sorbifer durules tab n / about 50 pc

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Description

Composition
Active substance:
Each film-coated tablet contains ferrous sulfate in an amount equivalent to 100 mg of Fe2 + and 60 mg ascorbic acid, as well as: magnesium stearate, povidone K-25, polyethene powder, Carbomer 934 P. The casing comprises: hypromellose, macrogol 6000, titanium dioxide, iron oxide yellow, solid paraffin.
Description:
round biconvex film-coated tablets pale yellow, engraved with “Z” on one side, at the turn of the core of a gray color, with a characteristic odor.
Product form:
Tablets, coated tablets, 50 tablets in a brown glass bottle.
1 vial together with instructions for medical applications put in a cardboard box.
Contraindications
Increased sensitivity to the drug.
Stenosis of the esophagus and / or gastrointestinal tract obstructive changes.
Increased content of iron in the body (hemosiderosis, hemochromatosis).
Improper disposal of iron (lead anemia, sideroblastic anemia, hemolytic anemia).
Children up to age 12 years (due to lack of clinical data).
Precautions: peptic ulcer and 12 duodenal ulcer, inflammatory bowel disease (enteritis, diverticulitis, ulcerative colitis, Crohn’s disease).
Indications
Iron-deficiency anemia.
Iron deficiency.
Prophylactic use during pregnancy, lactation and in blood donors.
Interaction with other drugs
Durules can reduce absorption simultaneously applied enoxacin, clodronate,
grepafloksatsina, levodopa, levofloxacin, methyldopa, penicillamine, tetracycline and thyroid hormones. Simultaneous application of the drug Sorbifer
Durules and antacid preparations containing aluminum hydroxide and magnesium carbonate, may reduce the absorption of iron. Between drug intake Sorbifer Durules and any of these drugs should withstand maximum possible time interval. The recommended minimum time interval between doses of 2 hours except receiving tetracyclines, when the minimum spacing should be at 3 hour. Sorbifer Durules should not be combined with the following medications: ciprofloxacin, doxycycline, norfloxacin and ofloxacin
Overdose
Symptoms: abdominal pain, vomiting and diarrhea mixed with blood, weakness or fatigue, pyrexia, paresthesias, pale skin, cold clammy sweat, acidosis, weak pulse, blood pressure, heartbeat. In severe overdosage symptoms of peripheral circulatory collapse, coagulopathy, hyperthermia, hypoglycemia, liver damage, kidney failure, muscle convulsions and coma can occur in 6-12 hours.
Treatment: In case of overdose, seek medical advice immediately. It is necessary to wash the stomach, orally egg, milk (for binding the iron ions in the gastrointestinal tract); administered deferoxamine. Symptomatic therapy.
pharmachologic effect
Pharmacological group:
iron preparation
Pharmacodynamics:
Iron – an essential component of the body necessary for the formation of hemoglobin and the flow of oxidative processes in living tissues. The drug is used to correct iron deficiency. Durules technology provides a gradual release of the active ingredient (iron ions) over time.
Plastic matrix tablets Sorbifer Durules completely inert in the digestive juice, but is completely disintegrated under the action of intestinal motility, when the active ingredient is fully released.
Pharmacokinetics:
Durules – a technology which provides a gradual release of the active substance (iron ions), a uniform delivery of the drug. Receiving 100 mg twice a day provides 30% more iron absorption from the formulation Sorbifer Durules compared with conventional iron preparations.
Absorption and bioavailability of iron – high. Iron is absorbed mainly in the 12-duodenum and proximal jejunum. Relationship to plasma proteins – 90% or more. Deposited in the form of ferritin and hemosiderin in hepatocytes and cells of macrophage phagocytic system, a minor amount – in the form mioglobiia muscle. The half-life is 6 hours.
Conditions of supply of pharmacies
On prescription.
side effects
Nausea, vomiting, abdominal pain, diarrhea, constipation. The frequency of side effects from the gastrointestinal tract may increase with increasing dose of 100 to 400 mg.
Seldom (
special instructions
Perhaps darkening of stool that has no clinical significance.
Pregnancy and lactation
Sorbifer Durules can be used during pregnancy and lactation.
Storage conditions
At a temperature of 15- 25 ° C, the reach of children.
Dosing and Administration
Coated tablets, are taken orally. They can not be divided or chewed.
Tablets should be swallowed whole and drink at least half a glass of liquid.
Adults and adolescents:
1 tablet 1-2 times a day.
If necessary, patients with iron deficiency anemia, the dose can be increased to 3-4 tablets per day in two divided doses (morning and evening) for 3-4 months (to replenish iron stores in the body).
Pregnancy and lactation:
Prevention: 1 tablet per day.
Therapeutic dose: 1 tablet 2 times a day (morning and evening).
Treatment should be continued until the optimum level of hemoglobin. For further replenishment depot may need to continue taking the drug for 2 months.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

EGIS

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