Sodium sulfatsil drops Ch. 20% 5ml Tub-cap. 1 PC

Description

Composition
Active substance:
1 ml contains: Sodium sulfacetamide – 200 mg.
Excipients:
Sodium thiosulfate – 1.5 mg, 1 M hydrochloric acid – to pH 7.7 to 8.7 Water for injection – up to 1 ml.
Product form:
Eye drops 20%. 5 mL or 10 mL in dropper bottles polymer. Each vial with instructions for use placed in a pile of cardboard.
Contraindications
Hypersensitivity.
Dosage
200 mg / ml
Indications
Conjunctivitis, blepharitis, corneal ulcer purulent, prevention and treatment of neonatal ophthalmia, gonococcal and chlamydial ocular diseases in adults.
Interaction with other drugs
Joint application with procaine and tetracaine reduces bacteriostatic effect. Incompatible with silver salts.
pharmachologic effect
Pharmacological group:
The antimicrobial agent – sulfanilamide.
Pharmacological properties:
Antimicrobial bacteriostatic agent, sulfanilamide. The mechanism of action caused by a competitive antagonism with para-aminobenzoic acid (PABA), inhibition digidropteroatsintetazy, tetrahydrofolic acid synthesis disorder necessary for the synthesis of purines and pyrimidines. Active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.
Pharmacokinetics:
It penetrates the tissue and eye fluid. It is absorbed into the systemic circulation through the inflammation of the conjunctiva. When applied topically, the maximum concentration in the cornea sulfonamides (about 3 mg / ml), moisture anterior chamber (about 0.5 mg / ml) and iris (about 0.1 mg / ml) is achieved within the first 30 min after application. Some amount (less than 0.5 mg / ml) is stored in the eyeball tissues for 3-4 hours. If the damage corneal epithelial penetration sulfonamides amplified.
Pregnancy and breast-feeding
Perhaps the use of sulfacetamide for treating pregnant women and nursing mothers prescribed by a doctor, if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Conditions of supply of pharmacies
Without recipe.
side effects
Burning, tearing, stinging, itching in the eyes, allergic reactions.
special instructions
Patients having enhanced sensitivity to furosemide, thiazide diuretics, carbonic anhydrase inhibitors, sulfonylurea or may be sensitive to sulfacetamide.
Storage conditions
In the dark place at a temperature of from 15 to 25 ° C. Keep out of the reach of children.
Dosing and Administration
Locally, 1-2 drops instilled in the conjunctival sac every 4-6 times per day. To prevent Infections in newborns – 2 drops into each conjunctival sac immediately after birth, and 2 drops – 2 hours.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist