Sanorin Nazal Spray. 0.1% 10ml vials. with crucified.

Description

Composition
Active substance:
Naphazoline nitrate 0.01g ;.
Excipients:
Ethylene q.s. (About 0.4 mg), boric acid O, 170 g, 0,010 g of methyl parahydroxybenzoate, water up to 10 ml.
Description:
Transparent, colorless liquid with no visible particles, odorless.
Product form:
Spreynazalny 0.1% 10 ml of the drug in matt translucent plastic bottle equipped with a mechanical screw-metering applicator with a protective cap and a plastic protective semicircle for protection against accidental operation. Each vial together with instructions for use placed in a cardboard box.
Contraindications
• hypersensitivity to the drug; • chronic rhinitis; • atrophic rhinitis; • closure glaucoma; • serious eye diseases; • arterial hypertension; • expressed atherosclerosis; • tachycardia; • hyperthyroidism; • diabetes; • simultaneous reception of monoamine oxidase inhibitors and up to 14 days after the end of application.
Sanorin About 05% solution is contraindicated in children under 2 years.
Sanorin, 1% solution is contraindicated in children under 15 years.
Carefully
Pregnancy, naktatsii, ischemic heart disease (angina), prostatic hyperplasia, pheochromocytoma.
Dosage
1 mg / ml
Indications
• coryza various etiology; • otitis media – as an additional means for reducing mucosal swelling nasopharynx; • sinusitis; • evstahiit; • laryngitis; • to reduce the swelling of the nasal mucous membranes, nasal and paranasal sinuses during diagnostic and therapeutic procedures; • If necessary, stop nosebleeds.
Interaction with other drugs
When applied simultaneously with the drug or monoamine oxidase inhibitors tricyclic antidepressants (prior to 14 days after application), may increase the blood pressure due to the release of catecholamines deposited under naphazoline. Therefore, simultaneous reception Sanorin drug with MAO inhibitors (and within 14 days after their withdrawal) is contraindicated.
Naphazoline slows the absorption of local anesthetics (prolongs their action).
Overdose
If overdose as a result of systemic effects on the organism can develop phenomena such as nervousness, sweating, headache, tremor, tachycardia, palpitations, and high blood pressure. Possible signs of overdose include nausea and cyanosis, increased body temperature, breathing and mental disorders. In the case of depression of the central nervous system are observed bradycardia, weakness, drowsiness, decreased body temperature, increased sweating, collapse, rarely coma may develop.
Treatment: symptomatic.
pharmachologic effect
Pharmacological group:
Decongestant agent alpha-agonists.
Pharmacodynamics:
Refers to naphazoline · alpha2 adrenoceptor agonists with direct stimulating effect on alpha · adrenoceptors of the sympathetic nervous system. Intranasal administration provides a rapid, pronounced and prolonged vasoconstriction action against vascular nasal mucous membranes, nasal and paranasal sinuses – reduces swelling and congestion, thereby improving the permeability of the nasal passages and nasal breathing is facilitated. At the same time restores patency of the Eustachian tubes. The therapeutic effect occurs, usually within 5 minutes after injection and lasts for 4-6 hours.
With prolonged use vasoconstrictive effect gradually decreases, and therefore the 5 x 7 days of treatment should take a break for a few days.
Pharmacokinetics:
Information concerning the distribution, metabolism and elimination nafazolina person does not have.
Pregnancy and breast-feeding
No data on the penetration nafazonina through the placental barrier and into breast monoko.
In this regard, the appointment of the drug is necessary to correlate the potential risk to the fetus and the child and the expected therapeutic effect for the mother.
Conditions of supply of pharmacies
Without recipe.
side effects
The recommended doses are usually well tolerated drug.
In sensitive individuals may feel burning and dryness in the nose.
In rare cases, after the cessation of exposure to the drug develops reactive hyperemia and swelling of the nasal mucosa.
As a result of stimulation of the sympathetic nervous system and the overall impact on the body rarely nausea, tachycardia, headache, irritability, sweating, allergic reactions, rash, increased blood pressure.
Long-term and frequent use (more than 1 week) Sanorin drug can lead to chronic disruption nasal patency and atrophy of the mucosa of the nasal cavity.
special instructions
Interactions with mono oxidase inhibitors enhances hypertensive effect. Caution must be exercised during general anesthesia with anesthetic agents that increase the sensitivity of the myocardium to sympathomimetics (halothane), especially in patients with bronchial asthma.
Avoid prolonged dosing.
Due to the possible development of adverse events associated with the cardiovascular and nervous systems should not exceed a dose Sanorin preparation, recommended for use.
Storage conditions
Store at a temperature of from 10 ° C to 25 ° C in a dark place.
Keep out of the reach of children.
Dosing and Administration
Intranasally.
1-3 dose in each nostril 3-4 times a day.
The first application of spray recommended repeatedly press the dosing device until the compact aerosol cloud. Before the direct application of clear protective cap, hold the vial in an upright position, the end portion of the metering device type in the nasal passage, and then sharply and quickly click on the applicator. Immediately after the injection is recommended for easy inhale nose. After applying the drug applicator close the protective cap.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist