Sanguirythrine alcohol solution. 0.2% 50ml vial

Description

Composition
Active substance:
1 liter of the preparation contains: sangviritrin – 2 g of (+ chelerythrine sanguinarine sulfate hydrogensulfate based on 100% basis).
Excipients:
Ethyl alcohol (ethanol) 95% – 315 ml Water to 1000 ml ochischennaya-.
Description:
Transparent liquid with orange smell of alcohol.
Product form:
Solution for local and external application [alcohol] 0.2%, dark glass vials of 50 ml.
Contraindications
Hypersensitivity to the drug, with symptoms of fungal eczematization. Liver and kidney dysfunction.
Dosage
2 mg / ml
Indications
Sanguirythrine used as an antimicrobial agent to the prophylactic and therapeutic purposes in children (including infants and children) and adults (including pregnant women in antenatal and postnatal periods).
As a preventive measure: in infants for the prevention of inflammatory skin diseases and in surgical patients – for the prevention of wound infection.
As therapeutic agents: in infectious and inflammatory diseases of the skin and mucous membranes of bacterial and fungal etiology, including Candida albicans, in dentistry – with periodontitis, aphthous stomatitis, gingivostomatitis necrotizing and other lesions of the oral mucosa; in otorhinolaryngology – angina, disorders of the middle ear and the external auditory meatus; in surgery – when infected burns, nonhealing wounds and ulcers; in gynecology – a drug prescribed for Endocervicitis, coleitis, vaginitis, cervical erosion; Dermatological – with pyoderma, surface blastomycosis, dermatomycosis and others.
Interaction with other drugs
It can be used in combination with local anesthetics (procaine, trimekain).
Overdose
To date, information on cases of overdose when using the drug have been reported.
pharmachologic effect
Pharmacological group:
The antimicrobial agent of vegetable origin.
Pharmacological properties:
Anticholinesterase, antiseptic, anti-inflammatory topical, Burns, stimulating tissue repair.
Pharmacodynamics:
Sanguirythrine obtained from herbs and makleyi macleaya cordata small-fruited poppy family. Sanguirythrine is a mixture of two bisulfates similar in structure and properties of quaternary benzophenanthridine alkaloids sanguinarine and chelerythrine.
Sanguirythrine has a broad spectrum of antimicrobial activity, acting against Gram-positive and Gram-negative bacteria, yeast and filamentous fungi. It is active against antibiotic-resistant strains of microorganisms. At therapeutic doses bacteriostatic. The basis of the mechanism of action of the antimicrobial drug is Sanguirythrine suppressing bacterial nuclease, disturbance of cell wall permeability processes, dividing walls, buildings nucleoid.
Pregnancy and breast-feeding
It is necessary to consult with your doctor.
Conditions of supply of pharmacies
Without recipe.
side effects
Possible local allergic reaction (skin redness).
When rinsing or lubricating aqueous preparation of oral mucous membranes – sensation of bitterness in the mouth, and for applying the drug to the wound area – transient burning sensation. In these cases, the drug is used at lower concentrations.
special instructions
As part of the product contains at least 27% ethanol.
Avoid contact with the drug on the mucous membranes of the eyes. After contact with the drug solution in the eye should be rinsed with plenty of water.
When nonhealing wounds and ulcers, endocervicitis, colpitis, vaginitis, cervical erosion, pyoderma, blastomycosis surface and dermatomycosis, including complicated mixed flora, possibly combined use of solutions of the drug in combination with a liniment formulation (0.5%), which is assigned in the form of bandages or smearing the lesion.
Storage conditions
In the dark place at a temperature not higher than 25 C.
Keep out of the reach of children.
Dosing and Administration
Topically, locally.
Neonatal drug treated skin folds 2 times a day during the first 5-6 days of life with a sterile cotton swab.
periodontitis treatment is carried out after the removal of dental plaque and curettage pathological gums. The gingival pockets administered 20 minutes turundy thin, heavily wetted drug or its aqueous solution. The aqueous drug solution is prepared immediately before use. To prepare the aqueous formulation is diluted to 40 times (1 teaspoon to 200 ml of warm water boiled). The procedure is repeated daily or every other day. The course of treatment is 4-6 treatments. When stomatitis of various etiologies mucosal lesions produce applique oral solutions of the drug 2-3 times a day for 2-5 days. Children older than 5 years are designated rinse with warm aqueous solution of the drug. Children under 5 years in stomatitis oral mucosa lubricated aqueous formulation.
With angina treated with tonsil preparation 1 times a day for 2-5 days. In addition, adults and children over 5 years, every day 3-5 times a day administered rinse with warm aqueous solution of the drug. Children under 5 years of this fluid lubricates the oral mucosa, 3-4 times a day. Duration of treatment 3-7 days.
When external otitis introduced into the auditory canal turundy soaked preparation for 10-15 minutes, 2-3 times per day. Minimum course of treatment two weeks. In chronic suppurative otitis media preparation is instilled 5-8 drops of adult, children – 1-2 drops 3-4 times a day.
For the prevention of inflammatory complications of the wound was treated daily with a sterile gauze pad, abundantly moistened drug covered with sterile cloth soaked with the same solution and put bandage fixation. After 3-4 days the wound re-treated with the drug and put a dry sterile dressing. The course is determined by the period of wound healing and uncomplicated application period is 7-10 days.
For treating infected burn, nonhealing wounds and ulcers, infected fractures and open al. Use aqueous preparation. Aqueous formulation washed wounds and ulcers, as well as bandages applied with the solution to the wound surface. When infected burns dressings produced in a day, while other injuries – every day 1-2 times a day. The duration of treatment depends on the nature and severity of the disease.
When Endocervicitis, coleitis, vaginitis, cervical erosion is carried out irrigation, irrigation and lotions warm aqueous solution of the drug on a daily basis 1-2 times a day. The course of treatment is 5-10 procedures.
When pyoderma, blastomycosis surface and dermatomycosis, including complicated mixed flora drug administered in the form of bandages or lubricating lesion daily 1-2 times a day. The duration of treatment depends on the nature and severity of the disease.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist