Rinzasip powder for r-ra 5g 5 pcs lemon / Vitamin C.

$4.84

Rinzasip powder for r-ra 5g 5 pcs lemon / Vitamin C.

Quantity:

Description

Composition
Active substance:
1 sachet contains: Ascorbic acid (Vitamin C) – 200 mg, caffeine – 30 mg paracetamol – 750 mg, phenylephrine hydrochloride – 10 mg, pheniramine maleate – 20 mg.
Excipients:
Orange: Citric acid 200.0 mg Sodium saccharin 40.0 mg Sodium Citrate 500.0 mg Sucrose 3062.5 mg, sunset yellow dye (E110) 7.5 mg 150.0 mg orange flavor;
lemon: Citric acid 200.0 mg Sodium saccharin 40.0 mg Sodium Citrate 500.0 mg Sucrose 3136.0 mg, quinoline yellow dye (E104) 1.0 mg Lemon flavor 83.0 mg;
blackcurrant: Citric acid 200.0 mg Sodium saccharin 40.0 mg Sodium Citrate 500.0 mg Sucrose 2915.0 mg, azorubin dye (E122) 4.0 mg, fruit flavoring (Tutti Frutti) 166.7 mg raspberry flavor 66.7 mg, 66.7 mg blackcurrant flavor.
Description:
Orange: the powder from light orange to orange with white and orange blotches;
Lemon: powder from light yellow to yellow in color with white and yellow patches;
Blackcurrant: powder pink to pinkish-red color with white and red patches.
Product form:
Powder for oral solution (orange, lemon, blackcurrant).
5g sachet of aluminum foil laminated with polyethylene and polyester.
At 5, 10 or 25 sachets together with instructions for use in a cardboard box.
Contraindications
Expressed atherosclerosis of the coronary arteries, portal hypertension, simultaneous tricyclic antidepressants, beta-blockers, inhibitors of monoamine oxidase (MAO) and termination of reception for at least 2 weeks ago; deficit sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption; Hypersensitivity to the individual components of the preparation, as well as sympathomimetic drugs; concurrent medication containing substances included in the formulation; pregnancy, lactation, children under 15 years of alcoholism.
Carefully
Heart diseases, hypertension, asthma, chronic obstructive pulmonary disease, emphysema, chronic bronchitis; thyroid diseases, diabetes, pheochromocytoma, blood diseases, deficiency of glucose-6-phosphate dehydrogenase, acute hepatitis, congenital hyperbilirubinemia (Gilbert syndrome, Dubin – Johnson and Rotor), hepatic and / or renal failure, simultaneous administration of drugs which could adversely affect the liver (e.g., inducers of microsomal liver enzymes), piloroduodenalnoy obstruction, stenosing gastric and / or duodenal ulcers, angle-closure glaucoma, epilepsy, hyperplasia presents t tatelnoy gland, as well as patients suffering from exhaustion and / or dehydration, the drug may be used with caution, after consultation with the doctor.
Indications
Symptomatic treatment “cold” diseases, influenza, SARS (febrile syndrome, pain, rhinorrhea).
Interaction with other drugs
Enhances the effects of inhibitors of monoamine oxidase (MAO), sedatives, ethanol.
When taken with digoxin or other cardiac glycosides may increase the risk of arrhythmias and myocardial infarction.
Antidepressants, antiparkinsonian agents, antipsychotics, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation. Corticosteroids increase the risk of developing glaucoma. Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxicity. Metoclopramide and domperidone to increase, and cholestyramine reduces the rate of absorption of paracetamol. Paracetamol reduces the effectiveness of diuretic and uricosuric drugs. When concomitant administration with barbiturates, phenytoin, carbamazepine, rifampicin and other inducers of microsomal liver enzymes increased risk of hepatotoxic action of paracetamol. The majority of patients receiving long-term warfarin, occasional use of paracetamol is usually little or no effect on the international normalized ratio (INR). However, with continued regular use paracetamol enhances the effect of anticoagulants (warfarin and other coumarin derivatives), which increases the risk of bleeding. Single administration of high doses of caffeine increases the lithium excretion by the kidneys. Abrupt cessation of caffeine may increase the concentration of lithium in blood serum.
If simultaneous reception with inhibitors of monoamine oxidase (MAO), furazolidone, pheniramine may lead to hypertensive crisis, excitation of hyperpyrexia.
When taken with MAO inhibitors phenylephrine can cause high blood pressure. Phenylephrine reduces the effectiveness of beta-blockers and action of antihypertensive drugs. Also it reduces the hypotensive effect of guanethidine, which, in turn, increases the activity of alpha-Adrenomimeticalkie phenylephrine.
Tricyclic antidepressants increase adrenomimeticheskoe effects of phenylephrine, co-administration of halothane increases the risk of ventricular arrhythmias.
Overdose
In case of overdose, you should immediately consult a doctor. Rapid medical assistance is critical, even if you do not notice any signs or symptoms.
Vitamin C
Symptoms of acute overdose include diarrhea and other gastrointestinal disorders.
Symptoms of chronic intoxication of ascorbic acid: impaired renal excretory function, the formation of kidney stones, decrease capillary permeability (possible deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathy, impaired iron metabolism), the erosion of tooth enamel.
Caffeine
Symptoms of acute overdose: abdominal pain, nausea, vomiting, fever, chills, headache, agitation, insomnia, irritability, loss of appetite, weakness, tremor, anxiety, altered state of consciousness, delirium, hallucinations, high blood pressure followed by hypotension, tachycardia, tachypnea, hypokalemia, hyponatremia, hyperglycemia, metabolic acidosis, seizures, convulsions, myoclonus, and rhabdomyolysis, supraventricular and ventricular arrhythmias.
Symptoms of chronic intoxication, caffeine, ( “caffeinism”): irritability, insomnia, anxiety, emotional lability, and chronic abdominal pain.
pheniramine
Symptoms: CNS depression, hyperthermia, anticholinergic syndrome (mydriasis, flushing, fever, dry mouth, urinary retention, intestinal paresis), tachycardia, hypotension, hypertension, nausea, vomiting, agitation, confusion, hallucinations, psychosis, convulsions , arrhythmia. Rarely, patients with agitation, seizures or coma patients in developing rhabdomyolysis and renal failure.
phenylephrine
Symptoms: headache, nausea, vomiting, irritability, agitation, insomnia, psychosis, convulsions, palpitations, tachycardia, increased blood pressure, reflex bradycardia.
Paracetamol
Symptoms appear after reception over 7.5-10 g: during the first 24 h after administration paleness of the skin, nausea, vomiting, anorexia, abdominal pain, an increase in prothrombin time, impaired glucose metabolism, hypokalemia, metabolic acidosis (incl . lactic acidosis). Symptoms of liver disease may occur through 12-48 hours after the overdose: increased activity “liver” enzymes, gepatonekroz. In severe cases, – hepatic failure with progressive encephalopathy, coma. Rarely hepatic insufficiency develops lightning and can be complicated by renal insufficiency (tubular necrosis).
overdose threshold may be reduced in elderly patients and children, patients taking certain medications (e.g., inducers of hepatic microsomal enzymes), alcohol or malnourished.
Treatment: gastric lavage, appointment of activated carbon in the first 6 hours after the overdose, administration donators SH-groups and precursors of glutathione synthesis – methionine through 8-9 hours after the overdose and acetylcysteine ​​- 12 hours The need for additional therapeutic activities (further administration of methionine. and acetylcysteine) depends on the concentration of acetaminophen in the blood, and the time elapsed after administration. Symptomatic therapy.
pharmachologic effect
Pharmacological group:
ARI and “cold” means eliminating symptoms (non-narcotic analgesic agent means psihostimulirutee + + H1-histamine receptor blocker + alpha + vitamin adrenoagonists).
Pharmacological properties:
Combined tool has antipyretic, analgesic, alpha-adrenostimuliruyuschee, vasoconstriction and antihistamine action, eliminates symptoms of “colds.”
Paracetamol – narcotic analgesics; blocking the cyclooxygenase (COX), mainly in the central nervous system, affecting thermoregulation, and pain centers; It has analgesic and antipyretic effect.
Phenylephrine – alpha-agonists with mild vasoconstrictor activity. Decreases edema and hyperemia of the mucous membranes of the upper respiratory tract and sinuses.
Pheniramine – blocker of H1-histamine receptors. It has antiallergic action: eliminates itching eyes, nose and throat, swelling and congestion of the mucous membranes of the nasal cavity, nasopharynx and sinuses, reduces exudative manifestations.
Caffeine has a stimulating effect on the central nervous system, enhances the analgesic effect, eliminates drowsiness and fatigue, increases physical and mental performance, reduces fatigue and drowsiness.
Ascorbic acid (vitamin C) is involved in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, in the synthesis of steroid hormones; It reduces the vascular permeability and increases resistance to the effects of various environmental factors.
Pregnancy and breast-feeding
In the absence of clinical data, safety of the drug during pregnancy and lactation has not been established, therefore, use of the drug in this category of patients is contraindicated.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions: skin rash, pruritus, urticaria, angioedema, hypersensitivity reaction, anaphylactic reaction.
From the nervous system: headache, dizziness, sleep, insomnia, drowsiness, irritability.
Cardio-vascular system: increased blood pressure, tachycardia, palpitations.
From the digestive system: nausea, vomiting, epigastric pain, dryness of the oral mucosa, elevated liver enzymes, hepatotoxicity.
From the senses: mydriasis, accommodation paresis, it increased intraocular pressure.
From the side of blood: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.
From the urinary system: renal toxicity (renal colic, Glycosuria, interstitial nephritis, papillary necrosis), difficulty urinating.
Other: bronchospasm, dry nasal mucosa.
Serious skin reactions:
Very rare: – Acute generalized exanthematous pustulosis (OGEP). Acute conditions with the development of pustular rash. Characterized by fever and diffuse erythema, accompanied by burning and itching. There may be a swelling of the face, hands and mucous membranes;
– & Johnson Syndrome Stevens (MICs) (malignant exudative erythema). Severe erythema multiforme form in which the bubbles emerge on the oral mucosa, throat, eyes, genital and other areas of skin and mucous membranes.
– Toxic epidermal necrolysis (TEN, Lyell syndrome). Syndrome is the result of extensive apoptosis of keratinocytes, which leads to large areas of skin peeling in places dermoepidermalnogo connection. Affected skin looks scalded with boiling water.
If you notice one of the above side effects, you should stop taking the drug and consult a doctor immediately !.
special instructions
During the period of treatment should refrain from drinking alcohol.
If symptoms worsen or persist for 5 days, and if there are new symptoms should consult a doctor.
The drug can cause drowsiness.
The drug contains sucrose, which should be considered in patients suffering from diabetes, as well as persons on a hypocaloric diet. In one unit dose formulation contains from 2,915.0 to 3,136.0 mg of sucrose, which corresponds 0,24-0,26 XE.
The drug can cause drowsiness. During the period of treatment should refrain from driving vehicles and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
Stored in a dry place at a temperature not higher than 25 C.
Keep out of the reach of children.
In case of ingestion of the drug a child should immediately seek medical help.
Dosing and Administration
Inside.
The contents of one sachet (the sachet) to pour into a beaker, add hot water and stir until completely dissolved and drink (optionally possible to add sugar or honey). The drug is recommended 1-2 hours after ingestion. Adults and children over 15 years: Take one sachet 3-4 times a day with intervals between meals 4-6 hours. The maximum daily dose – 4 bags. The course of treatment without consulting a doctor – not more than 5 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Rinzai

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