Retinol palms. oral solution an oil. 100tys.me / ml 10ml vial

Description

Composition
Active substance:
1 liter of the preparation contains: retinol palmitate (vitamin A) (100% by weight) 55.1 g
In 1 ml of solution contains 100 000 IU of retinol palmitate (1 drop of the preparation of a dropper or pipette, eye contains retinol palmitate, about 3300 IU). 1 mg of retinol palmitate 1817 IU corresponds.
Excipients:
Butylhydroxytoluene, butylhydroxyanisole, rapeseed oil to 1 l.
Description:
Transparent oily liquid from light-yellow to yellow color without rancid smell.
Product form:
Oral solution 100,000 IU / ml.
10, 15, 20, 30, 50, 100, 150, 200 ml vials of glass lighting. 10, 15, 20, 30, 50, in 100 ml flasks for a dark glass drops, complete with a dropper, and 150, in 200 ml amber glass bottles for drops.
Each vial with instructions for medical use in a stack of cardboard.
Contraindications
Increased sensitivity to the drug, hypervitaminosis A, pregnancy, gallstone disease, chronic pancreatitis, acute inflammatory skin disease.
Be wary of nephritis, cardiac insufficiency II-III art., Alcoholism, viral hepatitis, renal failure, in elderly, in children.
Indications
Hypovitaminosis, avitaminosis A. In complex therapy: of infectious and inflammatory diseases (measles, dysentery, flu, tracheitis, bronchitis, etc.), skin diseases and lesions (cracks, ichthyosiform erythroderma, acne, hyperkeratosis, seborrhoeic dermatitis, psoriasis, atopic dermatitis, some forms of eczema, lupus), eye diseases (retinitis pigmentosa, day-blindness, xerophthalmia, keratomalacia, eczematous lesions age), gastrointestinal disorders (erosive gastroduodenitis, gastric ulcer and duodenal to shki), liver cirrhosis.
Assign to prevent the formation of stones in the biliary and urinary tracts.
Interaction with other drugs
During prolonged therapy, tetracycline is not recommended for vitamin A (increased risk of intracranial hypertension).
Salicylates, and corticosteroids reduce the risk of side effects.
Cholestyramine, colestipol, mineral oil, neomycin reduce the absorption of vitamin A (higher doses may be required).
Oral contraceptives increase the concentration of vitamin A in plasma.
Isotretinoin increases the risk of toxic effects.
Vitamin E reduces toxicity, absorption, deposition in the liver. High doses of vitamin E may lower the stockpiles of vitamin A in the body.
Weakens the effect of calcium supplementation increases the risk of hypercalcemia.
Overdose
Long-term daily intake of vitamin A (100,000 IU children, 200,000 IU adults) can cause hypervitaminosis A. Symptoms of hypervitaminosis A in adults include headache, drowsiness, weakness, facial flushing, nausea, vomiting, pain in the bones of the lower limbs, impaired gait. Children can be observed: fever, drowsiness, sweating, vomiting, skin rashes. When the drug overdose symptoms should be abolished. Excess retinol palmitate is derived from an organism ingestion of alcohol. In stark expressed symptoms of intoxication should be appointed into steroids.
pharmachologic effect
Pharmacological group:
Vitamin.
Pharmacological properties:
Vitamin A has a bracing effect, normalizes tissue metabolism is involved in redox processes (due to a large number of unsaturated bonds), the synthesis of mucopolysaccharides, proteins, lipids, mineral metabolism, cholesterol formation processes. It enhances the production of the lipase and trypsin enhances myelopoiesis processes of cell division. It has a positive effect on the function of the lacrimal, sebaceous and sweat glands; increases the resistance to diseases of the mucous membranes of the respiratory tract and intestines; increases resistance to infection. Enhances division skin epithelial cell, rejuvenates cell population inhibits keratinization processes, enhances the synthesis of glycosaminoglycans, activates immune cells reacting with each other and epidermal cells. Stimulates cell regeneration. Involved in processes photoreception (promotes human adaptation to darkness). Local effects due to the presence on the surface of epithelial cells specific retinol receptor.
Pregnancy and breast-feeding
We do not recommend taking the drug during pregnancy and breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
In some patients with chronic administration are observed dryness of the skin and mucous membranes, increased sensitivity of the skin, binding. These phenomena are alone with dose reduction or temporary elimination of the drug.
In the treatment of acne after 7 – 10 days of aggravation observed local inflammatory response, which does not require additional treatment and subsequently stopped. In some cases, there is intolerance of the drug, which requires its cancellation.
special instructions
Do not take both multivitamin complexes containing vitamin A, in order to avoid overdose.
Storage conditions
In the dark place at a temperature not higher than 10 C. Keep out of reach of children.
Dosing and Administration
Use of the drug should be under a doctor’s supervision. The drug is taken orally after a meal early in the morning or late at night.
Therapeutic doses for adults with beriberi mild to moderate severity up to 33,000 IU / day for children 1000 – 5000 IU / day, depending on age.
With eye diseases prescribed for adults 50000 – 100000 IU per day, while 0.02 g of riboflavin.
In dermatology, the treatment of acne and ichthyosiform erythroderma in adults at 100,000 – 300,000 IU / day for children 5,000 – 10,000 IU / kg per day.
In diseases of the skin is prescribed for adults per day for 50,000 – 100,000 IU of retinol palmitate.
In gastroenterology – 50,000 IU per day.
Single doses of retinol palmitate should not exceed 50,000 IU for adults and 5,000 IU for children. Daily dose for adults is 100,000 IU and 20,000 IU for children. For the treatment of acne and ichthyosiform erythroderma in adults at 100,000 – 300,000 IU.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist