Prednisolone ointment appearance. 0.5% 15g tube

$0.75

Prednisolone ointment appearance. 0.5% 15g tube

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Description

Composition
Active substance:
100 g of ointment contains: prednisolone – 0.5 g
Excipients:
Distilled glycerin, petrolatum medical, stearic acid, emulsifier № 1, Nipagin, Nipasol, purified water.
Product form:
Tube 10 g or 15 g or 30 g.
Contraindications
Hypersensitivity to prednisolone or any of the components of the preparation, wound, ulcer, bacterial, viral, fungal skin lesions, open wounds, sores, skin post-vaccination reactions, tuberculosis, syphilis, skin tumors, acne vulgaris, acne rosacea (possibly exacerbation) pregnancy, lactation, children under 1 year.
If you have one of these diseases, before using the product, be sure to consult with your doctor.
Dosage
0.5%
Indications
The drug used in the treatment of inflammatory and allergic skin diseases nemikrobnoy etiology: urticaria, atopic dermatitis, chronic simple zoster (limited atopic), eczema, seborrhoeic dermatitis, discoid lupus erythematosus, simple and allergic dermatitis, drug reaction, erythroderma, psoriasis, alopecia.
pharmachologic effect
Pharmacological group:
Glucocorticosteroid agent.
Pharmacodynamics:
Prednisolone exerts anti-inflammatory, antiallergic, antipruritic and antiekssudativnoe action.
Reduces the formation, release and activity of inflammation mediators (histamine, kinin, lysosomal enzymes). Inhibits cell migration to the site of inflammation; reduces vasodilation and increased vascular permeability in inflammation.
Reduces exudation due to vasoconstrictor effect.
Suppresses macrophage action, target cells, cytokines that are involved in the development of allergic reactions such as contact dermatitis. Prevents access of sensitized T lymphocytes and macrophages to target cells.
Pharmacokinetics:
When applied topically and is absorbed prednisolone active substance into the bloodstream. In plasma, 90% of the prednisolone is in a bound form (with transcortin and albumin). Biotransformed by oxidation primarily in the liver; oxidized forms glyukuroniziruyutsya or sulfated.
Excreted by the kidneys and in bile as metabolites in part – unchanged.
It crosses the placental barrier and is found in small quantities in breast milk.
Pregnancy and breast-feeding
Glucocorticosteroids cross the placenta. During pregnancy, the drug is contraindicated.
Glucocorticosteroids are excreted in breast milk, so the period of treatment during lactation breastfeeding should be discontinued.
Conditions of supply of pharmacies
On prescription.
side effects
In applying the drug, particularly for patients with individual intolerance may be flushing, swelling, itching within the area of ​​application of the drug, steroid acne, telangiectasia, irritation, dryness of skin. With prolonged use of the drug may also develop secondary infections of the skin lesions, atrophic changes in it, hypertrichosis. For the prevention of infectious skin lesions drug recommended given in combination with antibacterial and antifungal agents.
With long-term use of the drug, especially on large areas of lesions may develop Cushing, as a manifestation of resorptive action of prednisolone. In these cases, medication overturned.
In the event of one or another adverse reaction as soon as possible consult a physician. If any of these instructions side effects are compounded or you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
Pediatric use.
In applying the drug in children aged 1 year and older should limit the total duration of treatment and eliminating activities that lead to increased resorption of absorption of the steroid (warming, fixing and occlusive dressings).
Be aware that small children skinfolds, diapers and diaper may have an effect similar to the effect of occlusive dressings, and increase systemic resorption of the active ingredient of the drug.
Due to the fact that in children the value of the ratio of surface area and body weight greater than that of adults, children are at greater risk of suppression of the hypothalamic-pituitary-adrenal system and the development of Cushing’s syndrome in the application of any corticosteroids for external use. Prolonged treatment with glucocorticosteroid may impair growth and development of the child. Therefore, children should receive the lowest dose of the drug to achieve the effect and use of the drug should be under the supervision of a physician.
The duration of drug should not exceed 14 days.
Can not be applied to the skin around the eyes (due to the possible development of glaucoma and cataracts).
In the case of the drug on the face area or under an occlusive dressing, as well as in children 1 year and older, duration of the course of treatment should be reduced.
Effects on ability to drive vehicles and management mechanisms.
The drug in the dosage form has no effect on ability to drive motor vehicles and other classes of potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
At temperatures above 25 ° C.
Dosing and Administration
Outwardly. The ointment is applied a thin layer to the affected skin 1 – 3 times a day.
The duration of treatment depends on the nature of the disease and the effectiveness of therapy, constituting, as a rule, 6 – 14 days. During the period of follow-up care may use the drug once a day.
In areas with thicker skin (e.g., elbows, hands, feet), and the location from which the drug is easily erased, an ointment may be applied more frequently.
In limited foci to enhance the effect can be used with occlusive dressings.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Russia

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