Portalak 66.7% syrup 250ml vials

Description

Composition
Active substance:
100 ml of syrup containing 66.7 g of lactulose concentrate.
Excipients:
Purified water.
Description:
Transparent viscous liquid from colorless to brownish-yellow.
Product form:
Syrup 667 mg / ml.
250 ml and 500 ml of the drug vial of high density polyethylene with a polypropylene screw cap, sealed with polyethylene foam ring. One vial together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity to lactulose or other ingredients, galactosemia, ileus, rectal bleeding (cause of which is not hemorrhoids) colonies, ileostomy, suspected appendicitis.
Indications
Constipation (including chronic) softening stool need for medical purposes (hemorrhoids, necessity of surgical operations on the colon and / or the anus, pain after removal of hemorrhoids, postoperative period) intestinal dysbiosis hepatic encephalopathy and hepatic coma precoma ( treatment and prevention of) enteritis hyperammonemia, caused by Salmonella, Shigella, salmonellonositelstvo; putrid dyspepsia syndrome (in young children as a result of acute food poisoning).
Interaction with other drugs
When using therapeutic doses of lactulose were noted clinically significant interactions with other drugs, however, it is not recommended PORTALAK within two hours after taking the other drug.
When simultaneous administration of lactulose can inactivate drugs will create an unfavorable environment (e.g., formulations comprising mesalazine) for which release in the colon.
Antibiotics (neomycin) and reduce the effect of antacids. The effect on the ability of control of vehicles and mechanisms
In PORTALAK recommended doses has no effect on the ability to control vehicles and mechanisms. Special instructions and precautions:
If constipation is not corrected within a few days of taking the drug, as well as the resumption of constipation after stopping treatment should consult a doctor.
Due to the presence in the product of small amounts of sugars (15 ml syrup to contain 1.7 g of galactose and lactose to 1 g) necessary to take precautions when administering the drug to patients with diabetes and lactose intolerance.
Precautions drug prescribed to patients with gastrocardiac syndrome. In this case, treatment is initiated with a low dose and gradually increase them to avoid bloating.
In the treatment of hepatic encephalopathy, especially in the initial phase of therapy, one can use other laxatives. Empowered bowel movements can lead to the erroneous conclusion that achieved an adequate dose for the treatment of encephalopathy.
Lactulose can be used safely in pregnant and lactating mothers.
Overdose
Taking too high doses can cause diarrhea and disturbance of water and electrolyte balance.
Treatment: removal of preparation.
pharmachologic effect
Pharmacological group:
Laxative.
Pharmacological properties:
Has hyperosmotic, laxative effect, stimulates intestinal motility, improve the absorption of Ca2 + and phosphate salts, contributes to the removal of ammonium ions. Under the influence of lactulose occurs reproduction Lactobacillus acidophilus, Lactobacillus bifidus in the intestine, which in turn leads to a decrease in pH in the colon lumen and enhance its peristalsis. Along with this increased volume and softening of stools. The drug has a laxative effect, without affecting directly to the mucosa and the smooth muscles of the colon.
Under the influence of lactulose reduces the formation of nitrogen-containing toxic substances in the proximal colon and their absorption into the systemic circulation.
The concentration of ammonium ions in the blood is reduced by 25 – 50%, reduces the severity of hepatic encephalopathy, improves mental state and normalizes EEG.
The preparation has the ability to inhibit the growth of Salmonella in the colon. Effect of the drug occurs within 24 – 48 hours after ingestion of the drug as it passes through the gastrointestinal tract.
Lactulose is practically not absorbed from the gastro-intestinal tract (not absorbed more than 3% of the dose) does not reduce the absorption of vitamins, non-addictive.
Conditions of supply of pharmacies
Without recipe.
side effects
Side effects are usually mild and reversible character and are due to excess dose. Cramping, discomfort or pain in the abdomen and diarrhea can be avoided by dose reduction.
Flatulence appearing at the beginning of treatment usually extends over 1 to 2 days.
Cases of skin reactions (rash).
When long-term therapy with high doses of lactulose in the treatment of hepatic encephalopathy may develop disruption of water-electrolyte balance, and as a result, cramps, nausea, headache, dizziness, arrhythmia, myalgia, fatigue, weakness.
Storage conditions
At temperatures above 25 ° C. Do not freeze because of a possible crystallization of lactulose!
Keep out of the reach of children!.
Dosing and Administration
Dose picked individually. In the treatment of constipation and for softening stools: initial dose (the first three days) is -children to 1 year, 5 ml syrup; Children from 1 year to 6 years, 5-10 ml of the syrup; children of 7 to 14 years, 15 ml syrup; adults -15-45 ml syrup. Continued treatment -children to 1 year, 5 ml syrup; Children from 1 year to 6 years, 5-10 ml of the syrup; children of 7 to 14 years, 10 ml syrup; adult-15-30 ml syrup.
The drug is best taken in the morning during or after a meal, once or divided into two doses. The drug can be washed down with water or other liquid. The patient can select and change the dose and time of receipt of the needs of the drug. The laxative effect of the drug develops within the first two days of admission.
Duration of treatment for constipation is from 4 weeks to 3-4 months.
In the treatment of liver (portal) encephalopathy, hepatic coma and precoma: 30-50 ml syrup (2-3 tablespoons) three times a day.
In the initial phase of treatment may be administered a dose of 30-45 ml syrup every 1-2 hours in order to achieve a rapid effect (first bowel movement). Then move on to the maintenance dose, selecting her individually to receive a soft stool 2-3 times a day.
In the treatment of dysbiosis and normalization of intestinal microflora:
The drug is administered during or after a meal, 2 – 4 times a day. Single doses comprise: children under 1 year of 1.5-3 ml syrup; Children from 1 year to 3 years, 3 ml of the syrup; children 3 to 7 years 5 ml syrup; adults and children over 7 years 5 – 10 ml of syrup. The duration of treatment is 10-14 days, refresher courses are assigned to weekly intervals.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist