Pimafutsin cream 2% 30g tube

Description

Composition
Active substance:
1 suppository contains: 100 mg of natamycin 1 tablet contains: 100 mg natamycin; 1 g of cream contains: 20 mg of natamycin.
Excipients:
1 suppository contains: 690 mg of cetyl alcohol, tallow 700 mg, 460 mg Triolit sorbitol, polysorbate 80 – 460 mg, sodium carbonate of Hydrogen 69 mg adipic acid 64 mg. 1 tablet contains: potato starch 79.2 mg polyvinylpyrrolidone 5 mg magnesium stearate 2.5 mg Lactose 66 mg, 3.3 mg gelatin, acacia (gum arabic), 7.3 mg of methyl-p-hydroxybenzoate 0.07 mg , 30 mg of calcium carbonate, kaolin 14.2 mg talc 21.7 mg cellulose acetate phthalate 18 mg triacetin 2.7 mg, white bees wax 0.13 mg titanium oxide 3 mg, sucrose 122 mg. 1 g of cream contains: V tsetiol 100 mg, wax based on 50 mg cetyl esters, cetostearyl alcohol, 135 mg, 15 mg sodium lauryl sulfate, methyl p-hydroxybenzoate 1 mg, 150 mg propylene glycol, purified water to 10 mg.
Description:
Vaginal suppositories: torpednoobraznoy shape, color from white to pale yellow.
Tablets coated with an enteric coating: White round tablets, coated tablets.
Cream: Cream homogeneous light shade.
Product form:
Tablets coated with an enteric coating, 100 mg, in a vial 20 tab.
Vaginal suppositories of 100 mg 3 blister units.
2% cream in a tube ’30
Contraindications
Increased sensitivity to the drug.
Indications
Fungal diseases of the skin and mucous membranes, caused by susceptible to malaria pathogens, including pseudomembranous .: acute and acute atrophic candidiasis in patients with cachexia, immune deficiency, or after treatment with antibiotics, corticosteroids, cytostatics; otomycosis, otitis externa, or primarily caused by fungi or complicate candidiasis; candidiasis of the skin and nails; intestinal candidiasis; vaginitis, vulvitis, vulvovaginitis, balanoposthitis, mainly caused by Candida fungi; ringworm.
The preparation may be used as an adjunct in the treatment of tinea griseofulvin.
Interaction with other drugs
Drug interaction Pimafutsin preparation is not described.
Overdose
Currently, the cases of drug overdose Pimafutsin were reported.
pharmachologic effect
Pharmacological group:
Antimicrobial, antiparasitic, and sedative, insecticides, repellents including: antifungal agents.
Pharmacodynamics:
The antifungal polyene macrolide antibiotic having a broad spectrum of activity. It has a fungicidal effect. Natamycin binds sterols of cell membranes, impairing their integrity and function, which leads to the death of microorganisms. For natamycin sensitivity of most pathogenic yeasts, particularly Candida albicans. Are less susceptible to natamycin dermatophytes. Resistance to natamycin in clinical practice does not occur. Natamycin in tablets, through the enteric coating acts only in the intestine.
Pharmacokinetics:
Natamycin is not absorbed from the gastrointestinal tract, through the intact skin and mucous membranes.
Pregnancy and breast-feeding
Pimafutsin possible to use during pregnancy and lactation.
Conditions of supply of pharmacies
Without recipe.
side effects
From the gastrointestinal tract: possible nausea and diarrhea (occurring during the first days of taking the pills and extending independently during treatment).
Local reactions: possible slight irritation, burning sensation (when using lotions, vaginal suppositories).
special instructions
Vaginal suppositories under the influence of body temperature rapidly dissolve to form a foam mass, which facilitates uniform distribution of the active substance.
In the case of chronic or recurrent infection topical treatment may be supplemented by the appointment of pills and creams.
Ethanol, which is part of the vaginal suppositories may cause hypersensitivity reactions. During menstruation suppositories therapy is discontinued, the period of treatment suppositories there is no need to exclude sexual intercourse. However, it is recommended to conduct a survey of sexual partners and, in the case of vulvovaginal lesions, hold treatment Pimafutsin. You should also provide for the use in treatment of barrier contraceptives. Pimafutsin can be administered to newborns.
Storage conditions
The drug should be stored at a temperature of from 15 to 25 C in the reach of children.
Dosing and Administration
When intestinal candidiasis adults appoint 1 tab. 4 times / day, for an average of 1 week.
Children appoint 1 tab. 2 times / day.
In dermatomycosis (including skin and nail candidiasis, diaper rash in children) cream applied to the affected surface of the skin and nails one or more times per day.
When otomycosis affected surface smeared with cream 1 or more times a day. Prior to use, clean the ear of the drug. After the drug is placed into the ear canal turunda natural material (cotton, wool).
When vaginitis, vulvitis, vulvovaginitis designate one vaginal suppository for 3-6 days. The suppository is administered to the vagina in a prone position, as far as possible, 1 time / day. overnight. When thrust during vaginitis caused by Candida albicans, further prescribed tablets into (1 tab. 4 times / day, during 10-20 days) for suction chamber Candida infection in the intestine.
For the treatment of vulvovaginal lesions genitals partner used Pimafutsin in the form of a cream.
When balanoposthitis cream is applied to the affected skin once or several times a day.
The duration of treatment is determined individually. After the disappearance of the symptoms it is recommended to continue treatment for several days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist