Pimafukort cream 15g tube

Description

Composition
Active substance:
1 g of cream contains: 10 mg natamycin, neomycin (as neomycin sulfate) 3500 IU, hydrocortisone, micronized 10 mg. 1 g of ointment contains: 10 mg natamycin, neomycin (as neomycin sulfate) 3500 IU, hydrocortisone, micronized 10 mg.
Excipients:
1 g of cream contains: 14.0 mg of sodium citrate, emulsifier F 115,0 mg, sorbitan stearate 30.0 mg, 60.0 mg tsetilefirny wax, tsetiol V 150,0, 20.0 macrogol stearate 100 mg methyl parahydroxybenzoate 2 0 mg propyl parahydroxybenzoate 0.50 mg purified water to 1000.0 mg. 1 g of ointment contains: Polyethylene ointment base (liquid paraffin 95%, 5% polyethylene) 976.5 mg.
Description:
Cream: Cream white to white with a yellowish tinge.
Ointment: ointment from white to yellow.
Product form:
Ointment and cream for external use:
15 g of aluminum or plastic tubes treated with epoxy lacquer, covered with aluminum membrane and a plastic screw-cap having means for piercing the membrane.
1 tube together with instructions for use in a cardboard box.
Contraindications
Hypersensitivity to the drug; lupus, cutaneous manifestations of syphilis, viral skin infection, post-vaccination reactions skin, open wounds, ulcers; acne, rosacea, ichthyosis; anogenital pruritus, skin tumors.
Carefully
With careful use in tuberculosis (systemic disease) – in children younger than 1 year; – in patients with a history of references to defeat IX pair FSK during treatment with aminoglycosides.
If there is perforation of the tympanic membrane and the direct effect of neomycin on the middle ear there is a risk Valium actions.
Indications
Dermatoses, measurable glucocorticosteroid therapy, complicated by secondary bacterial and / or fungal infections (especially caused by fungi of the genus Candida).
Interaction with other drugs
Drug interactions are not described.
There may be a cross between hypersensitivity drugs neomycin and similar chemical structure, for example kanamycin, paromomycin, gentamicin and neomycin cross-resistance between aminoglycosides and other antibiotics group.
Overdose
Information about drug overdose not. There is a theoretical possibility ototoksicheskogo neomycin when applying the product to the external auditory meatus region in the presence of perforation of the tympanic membrane and direct effect of neomycin on the middle ear.
pharmachologic effect
Pharmacological group:
Glucocorticoids + antibiotic-aminoglycoside + an antifungal agent.
Pharmacological properties:
Combined preparation has antibacterial, antifungal, local anti-inflammatory effect.
Neomycin is a broad-spectrum antibiotic of the aminoglycoside, is active against a number of Gram-positive (Staphylococcus spp., Enterococcus spp.) And gram-negative (Klebsiella spp., Proteus spp., Escherichia coli, etc.) Bacteria.
Natamycin belongs to the antifungal polyene series, has fungicidal activity against yeast and yeast-like fungi, particularly Candida spp. Dermatomitsetami to natamycin are less sensitive.
Hydrocortisone has anti-inflammatory. and vasoconstrictor activity.
Eliminates the inflammation and itching that accompany various types of dermatoses.
Pharmacokinetics:
Natamycin and neomycin substantially not absorbed through the intact skin and mucous membranes. Neomycin possible absorption through the damaged skin in contact with the drug on the wounds, ulcers. It absorbed through intact skin from 1 to 3% hydrocortisone; when the amount of absorbable dermatitis hydrocortisone increases 2 times, and infectious lesions of the skin can increase to 5 times. In children, the absorption of hydrocortisone through intact skin is higher than in adults, the degree of absorption of the drug into the systemic circulation decreases with age.
Pregnancy and breast-feeding
In the appointment of the drug during pregnancy should be considered a theoretical risk of ototoxic neomycin, and therefore can not use the drug for a long time, and to put it under occlusive dressings.
Conditions of supply of pharmacies
Without a prescription.
side effects
Side effects when applied externally pimafukort, as well as the application of other glucocorticosteroids, are rare and are reversible. Rarely may develop a hypersensitivity reaction (itching, burning, redness or dryness of the skin).
Very rarely – atrophy and thinning of the skin, telangiectasia, striae, purpura, rosacea-like and perioral dermatitis, slow wound healing, depigmentation, hypertrichosis, withdrawal symptoms after cessation of treatment.
When applying external glucocorticosteroids for a long time, over extensive areas of the skin, or when using occlusive dressings, especially in infants may develop side effects, typical of corticosteroids for systemic effects, such as suppression of adrenocortical function.
Contact dermatitis to neomycin.
special instructions
When applying pimafukort on the eyelids and periorbital area there is a risk of increasing intraocular pressure, cataract development.
In applying the drug over a large surface in children or under the bandages must be borne in mind the possibility of the suppression of the hypothalamic-pituitary-adrenal system.
In the case of long-term treatment, in the presence of wounds and ulcers there is a theoretical risk of ototoxicity and nephrotoxicity of neomycin.
When the super-infection or excessive growth of fungi should stop using the product and take appropriate action.
Storage conditions
At a temperature not exceeding 25 C. Keep out of reach of children.
Dosing and Administration
Adults and children formulation applied to the affected areas of skin 2-4 times a day. Duration of treatment is determined individually taking into account the nature of the disease, treatment usually does not exceed 14 days.
In children, the drug should be applied on a limited skin fate not use occlusive dressings. If there is no improvement in children and adults after 14 days, you should consult a doctor.
In the form of a cream preparation suitable for the treatment of acute and subacute dermatoses, including accompanied by weeping. The ointment is intended for the treatment of subacute and chronic dermatoses, especially in the presence of severe dry skin, lichenification, seborrhea or in cases where the required properties of the occlusive ointments.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist