Papaverine hydrochloride injectable solution 2% 2ml amp 10 pcs

Description

Composition
Active substance:
1 ml of solution contains: papaverine hydrochloride – 20.0 mg.
Product form:
Injectable solution 20 mg / ml.
Contraindications
Increased sensitivity to the drug, impaired atrioventricular conduction, glaucoma, severe liver failure, coma, respiratory depression, advanced age (risk of hyperthermia), children up to 6 months.
Dosage
2%
Indications
Spasm of smooth muscles of the abdominal cavity, bronchi, peripheral vascular and cerebrovascular disease, urinary tract, renal colic. As an auxiliary medicament for sedation.
pharmachologic effect
Pharmacological group:
Antispasmodic.
Pharmacological properties:
Papaverine reduces smooth muscle tone and has in connection with the vasodilator and antispasmodic action. An inhibitor of phosphodiesterase enzyme. It causes the intracellular accumulation of cyclic adenosine monophosphate and 3,5-reduction of calcium ions, which leads to relaxation of smooth muscles of inner organs (gastrointestinal tract, respiratory and urogenital system), and blood vessels. Papaverine action on the central nervous system is weak, but in large doses it has a sedative effect. In large doses, it reduces the excitability of the heart muscle and slows intracardiac conduction.
Conditions of supply of pharmacies
Prescription.
Dosing and Administration
Intramuscularly, subcutaneously or intravenously. A single dose of 12 years for adults and children is 20.0 – 40.0 mg (12 ml of a solution of 20.0 mg / ml); the interval between doses – at least 4 hours. Intravenous administration produced previously diluted papaverine solution (20.0 mg / ml) 10 – 20 ml of isotonic sodium chloride solution. For children aged 6 months to 12 years, the maximum single dose of 0.3 mg / kg body weight.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist