Otrivin express nasal spray 0.05% 10ml with menthol flavor

Description

Composition
Active substance:
Oxymetazoline hydrochloride 0.5 mg
Excipients:
Sorbitol 14.0 mg Sodium chloride 5.5 mg Hydrogenated castor oil 2.5 mg sodium dihydrogen phosphate dihydrate 2.0 mg, levomenthol (menthol) 2.0 mg, cineole (eucalyptol) 1.5 mg Disodium edetate dihydrate 0.5 mg benzalkonium chloride 50% solution of 0.2 mg (calculated as benzalkonium chloride 0.1 mg), disodium hydrogenphosphate dodecahydrate 0.1 mg purified water to 1.0 ml.
Product form:
Nasal spray, 0.05%; nasal spray with menthol flavor, 0.05%.
10 ml vial formulation of PVP, equipped with a spray device with a tip and a polypropylene screw cap of polyethylene. The vial together with instructions for use placed in a cardboard box.
Dosage
0.5 mg / ml
Indications
Symptomatic treatment of nasal congestion with acute respiratory diseases with symptoms of rhinitis (common cold), acute allergic rhinitis, hay fever, sinusitis, evstahiita, otitis media (to reduce nasopharyngeal mucosa edema). In order to facilitate the outflow of secretions in diseases of the paranasal sinuses. Preparing the patient for diagnostic procedures in the nasal passages.
Overdose
In case of overdose of oxymetazoline for the clinical picture is characterized by: mydriasis, nausea, cyanosis, fever, tachycardia, cardiac arrhythmia, heart failure, hypertension, pulmonary edema, shortness of breath, mental disorders, hallucinations, seizures. You may also receive the symptoms associated with depression of the central nervous system, ie. C. Drowsiness, drop in body temperature, bradycardia, hypotension, shock-like, and loss of consciousness.
To reduce the blood pressure can be applied nonselective adrenergic antagonists, in particular phentolamine. Severe cases may require intubation and mechanical ventilation. In the case of moderate or severe overdosing due to accidental oral activated charcoal and sodium sulphate (laxative), after considerable overdose prescribed gastric lavage. Displaying symptomatic therapy. The use of vasopressors contraindicated.
pharmachologic effect
Pharmacological group:
Decongestant agent – alpha-agonists.
Pharmacodynamics:
Otrivin® Hydroxy (oxymetazoline) – sympathomimetic agent acting on alpha – adrenergic receptors of the nasal mucosa. It has vasoconstrictor action, reducing the swelling of the mucosa of the nasopharynx. When applied topically to the inflamed nasal mucosa decreases its swelling and nasal discharge. Restores nasal breathing, eliminates swelling of nasal mucosa, the recovery aeration nasal sinuses, middle ear cavity, which reduces the likelihood of bacterial complications (sinusitis, sinusitis, otitis media). For topical intranasal application of therapeutic concentrations oxymetazoline has no systemic action, non-irritating and does not cause flushing nasal mucosa.
The drug takes effect after 25 seconds, the effect is maintained until 12 hours.
Pharmacokinetics:
For topical intranasal application oxymetazoline has no systemic action. Suction oxymetazoline regarded as having no clinical significance.
Pregnancy and breast-feeding
Otrivin Oxy is contraindicated in pregnancy because of the potential systemic vasoconstrictor effect.
During breastfeeding formulation should be applied only after careful evaluation of risk-benefit ratio for the mother and fetus is not permitted to exceed the recommended dosage.
side effects
When using the drug according to the instructions of side effects were observed, but when the solution residues were not thoroughly rinsed from the prosthesis, hyperemia observed in patients oral mucosa, as well as irritation and burning sensation at the site location of the prosthesis.
Storage conditions
at a temperature not higher than 25 ° C. Keep out of the reach of children.
Dosing and Administration
Internazalno. Adults and children over 12 years: 1 injection in each nostril 1-2 times a day. Do not apply more than twice per day. Before first use spray nasal spray several times until a uniform distribution of the drug.
1. Do not cut the tip of the spray device.
2. Thoroughly clean the nose.
3. Remove the protective cap. Take the vial vertically supporting the bottom of the thumb, a nozzle is located between the middle and index fingers.
4. Aim the nozzle into the nostril, tilted slightly forward vial.
5. Click the spraying device spraying the drug and at the same time inhale through the nose.
6. Repeat for the other nasal passage.
7. After the application should be clean and dry nozzle before the protective cap to close it.
At the recommended dose without consulting your doctor, do not use more than 7 days. Do not exceed the recommended dosage.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist