Ostenil solution and / in / with 20mg / 2ml 2ml shpr.got


Ostenil solution and / in / with 20mg / 2ml 2ml shpr.got



Active substance:
1 ml of an isotonic solution containing 10.0 mg sodium hyaluronate and sodium chloride, sodium monohydrogenphosphate, sodium dihydrogenphosphate, water for injection.
This means the original hyaluronic acid is used for local therapy of primary I-III osteoarthritis of the knee level, hip and shoulder joints. It is also applicable when the secondary post-traumatic arthritis or arthritis of other origin (in remission).
Product form:
A pre-filled syringe 20 mg / 2.0 ml of Austen (10 mg / 1.0 ml of Austen-mini) in sterile
It should not be used by patients suffering from a pronounced sensitivity to one of the components.
Precautions: Special attention should be patients with hypersensitivity towards the drug. Observe the general precautions for intra-articular injections. Ostenil should be carefully introduced into the cavity of the joint .Neobhodimo avoid getting the drug into the blood vessels or surrounding tissues! Since there are no clinical data on the use of hyaluronic acid in children, Ostenil not recommended for use by pregnant women and nursing mothers, as well as patients suffering from inflammatory diseases such as rheumatoid arthritis or Bechterew’s disease. Do not use the drug in case the pre-filled syringe or sterile pack are damaged.
10 mg / ml
Intra Austen indicated for pain and restricted mobility in degenerative and traumatic changes of the hip, the knee joint and other synovial joints.
Interaction with other drugs
To date there is no evidence of incompatibility Ostenil with other solutions for intra-articular use. To facilitate the condition of the patient can take oral analgesics or anti-inflammatory drugs during the first few days of treatments.
pharmachologic effect
The synovial fluid that is viscoelastic due to the presence of hyaluronic acid, is found in all synovial joints, in particular in heavy bearing joints where it provides normal painless movement due to its lubricating and damping properties. It is also responsible for the nutrition of the cartilage. In the case of disorders associated with damaged joints, for example osteoarthritis, viscoelasticity of the synovial fluid is significantly reduced, thus reducing the lubricating and cushioning function. This leads to an increase in mechanical stress on the joint and cartilage destruction, which eventually leads to pain and limited mobility of the affected joint. Addition of synovial fluid by means of intra-articular injections of highly purified hyaluronic acid can improve the viscoelastic properties of synovial fluid. This improves the lubricating and cushioning function, and reduces the mechanical stress on the joint. As a rule, this leads to a decrease in pain and improving joint mobility, which may last for at least several months after a treatment cycle of five intra-articular injections.
side effects
Local secondary phenomena such as pain, feeling of heat, redness and swelling may occur at the joint into which the Ostenil. Imposition of ice on the joint for five – ten minutes to remove all such phenomena.
Storage conditions
Store at a temperature below 25 ° C. Do not use after the expiration date printed on the box. Keep out of the reach of children.
Dosing and Administration
Injections Ostenil made at the affected joint once a week, but for a maximum of 3 to 5 injections (Ostenil mini-: 1-3 injections). At the same time you can treat several joints. Depending on the severity of the joint disease, the positive effects of a treatment cycle of five intra-articular injections for at least six months. Repeated cycles of treatment can be conducted on demand. In the case of joint effusion recommended to reduce its volume by removing fluid from the cavity, rest, application of ice and / or intra-articular corticosteroid injection. Ostenilom treatment can be initiated in two – three days. The content and the outer surface of the pre-filled syringe Austen maintain sterility until until a broken package. Remove the pre-filled syringe out of the package, remove the Luer cap from the syringe, put the desired cannula (for example 19 or 21 G) and secure it by turning slightly. Before injection release air bubbles from the syringe.
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg


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