Oralsept spray mest.prim. scrapper. 0.255mg / dose 30ml 176doz 1 piece

$5.38

Oralsept spray mest.prim. scrapper. 0.255mg / dose 30ml 176doz 1 piece

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SKU: 2122780944 Categories: , , Tags: ,

Description

Composition
Active substance:
1 dose comprising: benzydamine hydrochloride – 0,255 mg.
Excipients:
Methyl parahydroxybenzoate – 0.17 mg, 96% ethanol – 17.00 mg, glycerin (glycerol) – 8.50 mg Peppermint flavor 27198/14 – 0.17 mg Sodium saccharinate – 0.0408 mg polysorbate 60 – 0.0085 mg sodium hydrogencarbonate – 0.0034 mg, quinoline yellow 70 dye (E 104) – 0.0034 mg, 85% dye indigotine (E 132) – 0.00017 mg purified water to 170 microliters.
Description:
The clear solution is yellow-green color with flavor peppermint.
Product form:
Spray for topical application dosage of 0.255 mg / dose.
30 ml (176 doses) in a plastic, white, opaque container with the dispenser and the folding tip.
Each container together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity to benzydamine or other components of the formulation.
Children up to age 3 years.
Carefully.
Increased sensitivity to aspirin or other nonsteroidal antiinflammatory drugs.
Bronchial asthma (including history).
Dosage
0.255 mg / dose
Indications
Symptomatic therapy of oral pain and inflammatory diseases of upper respiratory tract (different etiology):
pharyngitis, laryngitis, tonsillitis;
gingivitis, glossitis, periodontitis, stomatitis (including after radiotherapy and chemotherapy);
calculous inflammation of the salivary glands;
after treatment or removal of teeth;
after surgery and trauma (tonsillectomy, jaw fractures);
candidiasis of the oral mucosa (in combination therapy);
In infectious and inflammatory diseases requiring systemic treatment, drug ORALSEPT® used in a combination therapy.
Interaction with other drugs
It has not been studied. Not applicable pharmaceutical preparation ORALSEPT® incompatibility with other drugs.
Overdose
To date, cases of drug overdose ORALSEPT® were reported. However, it is known that benzydamine Accidental ingestion at high doses (hundreds of times exceeding the therapeutic one), especially in children, can cause excitation, convulsions, tremor, sweating, vomiting, and ataxia. Such acute overdose requires immediate gastric lavage, restoring fluid and electrolyte balance, symptomatic treatment, adequate hydration.
If you have taken more than the recommended dose, rinse the mouth with plenty of water, with the appearance of side effects, contact your doctor.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug (NSAID).
Pharmacodynamics:
Benzydamine hydrochloride – a non-steroidal anti-inflammatory agent, an indazole derivative, without a carboxyl group. The absence of the carboxyl group gives the following features: Benzydamine is a weak base (whereas most NSAIDs weak acid) has high lipophilicity, the gradient pH penetrates well into the inflammatory focus (wherein pH below) and stored at therapeutic concentrations.
Anti-inflammatory and local anesthetic effect, antiseptic (against a broad spectrum of microorganisms), as well as antifungal activity.
The anti-inflammatory effect of the drug caused by decrease capillary permeability, stabilization of cell membranes due to inhibition of synthesis and inactivate prostaglandins, histamine, bradykinin, cytokines, complement factors and other endogenous nonspecific “damaging” factors.
Benzydamine inhibits the production of proinflammatory cytokines, particularly of tumor necrosis factor? (TNF-?), To a lesser extent IL-1-beta (IL-1 beta). Benzydamine main feature is that being a weak inhibitor of prostaglandin synthesis, it demonstrates the potent inhibition of proinflammatory cytokines. For this reason, benzydamine may be classified as anti-inflammatory drug tsitokinpodavlyayuschy.
Valium action of benzydamine is associated with structural features of its molecules, like local anesthetics. Analgesic effect is caused indirectly decrease the content of biogenic amines having algogenov properties, and an increase in pain threshold of the receptor unit; benzydamine also block interaction with tissue bradykinin receptors, restores microcirculation and reduce pain sensitivity in inflammation.
Benzydamine has antibacterial action due to the rapid penetration through the membrane of microorganisms with consequent damage to cell structures, disturbance of metabolic processes and cell lysosomes.
It has an antifungal activity against 20 strains of Candida albicans and non-albicans strains causing structural modification of the cell wall of fungi and their metabolic chains, thereby preventing their reproduction.
Pharmacokinetics:
The local application is readily absorbed through mucous membranes and rapidly penetrates into the inflamed tissue is found in blood plasma in an amount insufficient to produce systemic effects. Derived mainly through the kidneys and intestines as metabolites or conjugation product.
Pregnancy and breast-feeding
Data on animal studies with respect to effects during pregnancy and lactation is not sufficient, and adequate and well-controlled studies in pregnant women have not held, moreover, unknown penetrates whether benzydamine in breast milk, therefore, the potential risk for humans can not It is determined.
Pregnancy and lactation ORALSEPT® drug is used only after consultation with your doctor, if the intended benefits to the mother outweighs the potential risk to the fetus and child.
Conditions of supply of pharmacies
Available without prescription.
side effects
Local reactions: dry mouth, numbness, burning sensation in the mouth.
Allergic reactions: hypersensitivity reactions, including skin rash, pruritus, urticaria, photosensitivity, angioedema, anaphylactic reactions.
Other: laryngospasm.
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
In applying the drug ORALSEPT® may develop hypersensitivity reactions. In this case, it is recommended to discontinue treatment and consult a doctor, for the appointment of appropriate therapy. If there is ulceration of the mucous membrane of the oropharynx, the patient should seek medical advice if symptoms persist for more than three days. Use of the drug ORALSEPT® not recommended in patients with hypersensitivity to aspirin or other nonsteroidal antiinflammatory drugs. ORALSEPT® drug should be used with caution in patients with asthma, as in this case may develop bronchospasm.
Avoid spray contact with eyes. After contact with the spray in your eyes, rinse them with plenty of water.
Effects on ability to drive and use machines.
The drug has no effect on the ability to drive, the performance of potentially hazardous activities that require high concentration and psychomotor speed reactions or an activity that requires special attention.
Storage conditions
Store at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Applied topically.
One dose corresponds to 1 spray pressing. One dose corresponds to one inhalation and is equivalent to 0.17 ml of solution.
Adults and children over 12 years: 4-8 doses 2-6 times a day.
Children aged 3-6 years: 1 dose of 4 kg body weight (maximum – 4 doses) 2-6 times a day.
Children aged 6-12 years: 4 doses 2-6 times a day.
Do not exceed the recommended dosage. Before applying, please consult your doctor.
A course of treatment:
inflammatory diseases of the oral cavity and pharynx from 4 to 15 days;
at odonto-stomatological pathologies: 6 to 25 days;
after surgery and trauma (tonsillectomy, mandible fracture) from 4 to 7 days.
Using the drug for long periods, it is necessary to consult a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Selba

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