Onihelp Nail Varnish 5% 5ml 1 piece

Description

Composition
Active substance:
1 ml of solution contains: amorolfine hydrochloride 55.74 mg (corresponding to 50 mg amorolfine base).
Excipients:
Ethanol – 482.53 mg, ethyl acetate – 144.59 mg Eudragit RL 100 (methyl methacrylate trimetilammonioetilmetakrilata chloride and ethyl acrylate copolymer [2: 0.2: 1]) – 127.60 mg, n-butyl acetate – 50.08 mg triacetin – 10.45 mg.
Description:
The clear solution from colorless to pale yellow.
Product form:
Nail Varnish 5%.
2.5 ml and 5 ml vial of dark glass, a plastic cap with an overlay of a polymeric material which prevents the drug from drying out, and to control the first ring opening. One vial together with instructions for use, alcohol wipes 30 in a hermetically sealed envelope made of aluminum foil, saws 60 and 10 applicators were placed in a cardboard box.
Contraindications
Hypersensitivity to amorolfine and other ingredients.
Age up to 18 years.
Dosage
50 mg / ml
Indications
• treatment of fungal nail infections caused by dermatofigami, yeasts and molds; • prevention of fungal nail infections.
Overdose
The drug for external application, however, in case of accidental contact with the drug should be flushed into the stomach and have symptomatic treatment.
pharmachologic effect
Pharmacological group:
Local antifungal.
Pharmacodynamics:
Antifungal agent for external use. It has fungistatic and fungicidal action due to damage of the cytoplasmic membrane by disrupting fungal sterol biosynthesis. Ergosterol content is reduced, accumulated content atypical sterically nonplanar sterols.
It has a wide spectrum of action. Highly active against the most common and rare pathogens of fungal nail infections: dermatophytes Trichophyton spp, Microsporum spp, Epidermophyton floccosum;.. yeast fungi Candida spp .; fungi Alternaria spp., Scopulariopsis spp., Hendersonula spp .; fungi of the family Dematiaceae Cladosporium spp .; insensitive species Aspergillus, Fusarium, Micorales.
Pharmacokinetics:
When applied on the nails penetrate the nail plate and further into the nail bed, almost entirely within the first 24 hours. The effective concentration is maintained in the affected nail plate within 7-10 days after the first application. Systemic absorption is negligible: plasma concentration is below the detection limit of determination methods (less than 0.5 ng / ml).
Pregnancy and breast-feeding
It is not recommended to use the drug during pregnancy and breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
To indicate the incidence of side effects uses the following classification: very often (> 10%), frequent (> 1%, and
special instructions
• nail files used for the treatment of the affected nails should not be used for the treatment of healthy nails! • During treatment should avoid the use of decorative nail polish and artificial nails overhead. • Do not allow the lacquer to reach the eyes, ears and mucous membranes. • Napkin contains flammable. • persons working with organic solvents (e.g., solvents for paint, gasoline, kerosene, etc.), Should wear gloves sealed to protect the coated nail varnish. • To prevent drying varnish should tightly close the lid after use. To cover from sticking, to avoid getting polish on the thread. • If you missed the lacquer, it should not be applied in excessive amounts of several layers, enough to continue treatment according to the instructions for use. • Do not pour the remaining drug in the place of discharge of water or waste. • Patients with conditions that predispose to the development of fungal nail infections (violation of the peripheral circulation, diabetes, immune deficiency), as well as patients with dystrophy of the nail before applying the drug is recommended to consult a doctor.
Storage conditions
At a temperature of not higher than 30 ° C. The vial should be stored tightly sealed, in a vertical position, away from the heat source.
Keep out of the reach of children!.
Dosing and Administration
Outwardly. Applied to the affected nails of fingers or toes 1-2 times a week as follows: 1. Before applying the varnish must be removed with scissors Onihelp® maximum possible number of the affected nail and carefully processed using the enclosed nail file, nail the affected areas on its surface. 2. The surface of the nail, clean and degrease the supplied alcohol swab. 3. Dip the applicator into the varnish. The applicator should be removed from the vial without touching his neck, and should not be washed of excess varnish bottle neck. 4. The varnish applied to the affected nail surface with an applicator. 5. Tightly close the bottle with varnish immediately after use to prevent it from drying out. 6. After use, wipe applicator cloth. Throw the used tissue. 7. Writing varnish to dry for approximately 3-5 minutes.
The above procedure should be performed for each affected nail.
Before each subsequent application of the drug must Onihelp® alcohol swab to remove the previous layer of varnish, to process the sawing nails, and then clean and degrease the surface using an alcohol wipe.
Treatment should be carried out continuously until the complete cure of the lesion and the regeneration of nail plate.
If you forget to apply varnish on the scheduled day, it must be applied in the near future.
Duration of treatment is usually 6 months for fingernails and from 9 to 12 months for toenail.
If within 3 months of improvement does not occur, it is recommended to consult a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist