Ofloxacin eye drop-solofarm / 0.3% 5ml ushn-cap vial. 1 PC

$2.28

Ofloxacin eye drop-solofarm / 0.3% 5ml ushn-cap vial. 1 PC

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SKU: 0144160014 Categories: , , Tag:

Description

Composition
Active substance:
1 ml of the preparation contains:
Ofloxacin 3.0 mg.
Excipients:
Sodium dihydrogen phosphate dihydrate 13.22 mg, Sodium hydrogen phosphate dihydrate 8.01 mg
Benzalkonium chloride 0.05 mg Water for injection to 1.0 ml.
Description:
Transparent colored liquid.
Product form:
Eye drops and ear 0.3%.
5 ml in a vial with a dropper of low density polyethylene and the lid from the first control opening of the vial or dropper, high density polyethylene together with the lid and screwed plug-dropper.
1 bottle together with instructions for use in a stack of cardboard.
Contraindications
-Increased sensitivity to the drug and other derivatives of quinolones; – non-bacterial disease adnexa eye, the anterior and posterior segment of the eye; – non-bacterial otitis media; – Children’s age (up to 1 year); – pregnancy, breast-feeding.
With care – children’s age.
Dosage
0.3%
Indications
Ophthalmology
Bacterial anterior segment of the eye infections caused by susceptible microorganisms to ofloxacin in adults and children aged 1 year and older: corneal ulcers, conjunctivitis, dacryocystitis, meybomit (barley), chlamydial infections of the eye; prevention and treatment of bacterial infection after eye injuries and surgeries.
ear infections
Ofloxacin – SOLOfarm indicated for the treatment of bacterial infections caused by pathogens sensitive to ofloxacin in adults and children aged 12 years and older: – otitis externa, chronic suppurative otitis media, including perforation of the tympanic membrane; – prevention of infectious complications in surgical interventions for adults; – otitis externa and otitis media with tympanostomy tubes in children 1 to 11 years.
It should take into account official recommendations on the use of antimicrobials.
Interaction with other drugs
Magnesium, aluminum, iron and zinc reduce the absorption of ofloxacin.
Overdose
After topical application of excessive doses eyes should be rinsed with clean water at room temperature. Information about the system displays no overdose.
pharmachologic effect
Pharmacological group:
The antimicrobial agent – fluoroquinolone.
Pharmacodynamics:
The antimicrobial agent of a broad spectrum fluoroquinolone acts on the bacterial enzyme DNA gyrase, which provides supercoiling and thus the stability of the DNA of bacteria (destabilization DNA chains leads to their destruction). It has a bactericidal effect. It is active against microorganisms, producing beta-lactamase, and fast-growing atypical mycobacteria.
Sensitive: Staphylococcus aureus (including strains), Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Enterococcus faecalis, Corynebacterium spp, Micrococcus spp, Bacillus spp, Enterobacteriaceae (Escherichia coli, Citrobacter, Enterobacter spp, Klebsiela spp, Proteus spp….. ., Salmonella spp., Serratia spp., Shigella spp.),
Pseudomonas aeruginosa and Pseudomonas species, Haemophilus influenza, Haemophilus ducreyi, Branhamella catarhalis, Neisseria gonorrhoeae, Neisseria menengitidis, Acinetobacter spp., Sampylobacter spp., Gardenerella vaginalis, Helicobacter pylori, Brucella spp. The drug is also active against Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma pneumoniae, and certain other mycoplasma. Clostridium species, Bacteroides species Peptococcus species and possess resistance. Resistance of Pseudomonas aeruginosa varies between 15-20%, and Staphylococcus aureus resistance between 5-10%.
Pharmacokinetics:
After 4 hours after topical application mean concentration of ofloxacin in the lachrymal fluid is greater than 2 ug / mL (minimum concentration needed to inhibit in vitro growth by 90% for the most common strains of infectious eye diseases – MIC90). Instillation of ofloxacin in the ear in the case of an intact eardrum accompanied by a minimal absorption in the middle ear. However, ofloxacin absorption increases with perforation of the eardrum. After instillation of 0.3% ofloxacin solution adults with perforation of the eardrum maximum serum concentration is 10 ng / ml. The maximum serum concentration of ofloxacin after 10 days of regular topical 1000 times less than standard doses of ofloxacin inside.
Pregnancy and breast-feeding
Contraindicated for use during pregnancy and lactation.
Conditions of supply of pharmacies
Prescription.
side effects
After introduction into the conjunctival sac can: transient burning sensation or discomfort in the eye, conjunctival hyperemia, blurred vision, eye pain, itching sensation.
When used in the form of ear drops may cause itching and bitter taste in the mouth. It is rarely possible: eczema, paraesthesia, dizziness, pain in the ear, a feeling of ringing in the ears, dry mouth.
special instructions
As is the case with other antimicrobials, ofloxacin prolonged use may lead to the growth of flora insensitive thereto. Therefore, in the absence of clinical improvement within the standard period of treatment or to cancel deterioration preparation and start alternative therapy.
Contact lenses should be removed before instillation of the preparation and setting once again 20 minutes after instillation. The drug should not be injected subconjunctivally or anterior chamber.
Effects on ability to drive vehicles and mechanisms:
Patients who, after use of the drug in the eyes there is a short break-definition visual perception should not drive vehicles and mechanisms within 15 minutes after treatment.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
Locally.
Infectious diseases of the eye
The drug instilled 1 drop into the conjunctival sac of the patient eye 2-4 times per day. It is not recommended to use the drug for more than 2 weeks.
ear infections
Adults and children over 12 years
The frequency of use of the drug and duration of treatment are determined individually by your doctor.
Typically, in the case of otitis externa instilled 10 drops in the affected ear 2 times a day for 10 days.
In the treatment of chronic suppurative otitis media with perforation of the eardrum chronic recommended dose is 10 drops in the affected ear 2 times a day for 14 days.
Children aged 1 to 11 years
The frequency of use of the drug and duration of treatment are determined individually by your doctor.
For the treatment of otitis externa and otitis media with tympanostomy tubes recommended dose is 5 drops in the affected ear 2 times a day for 10 days.
Before instillation bottle should be warm in hand for 1-2 minutes to avoid the development of vertigo (possibly using cold solution). Instillation produced with the patient lying on his side. After instillation of the patient should maintain this position for 5 minutes to facilitate the passage of the solution through the external auditory meatus. If necessary, in the other ear instillation operate similarly.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Grotex Ltd.

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