Oflomil antifungal nail 5% 2.5ml 1 piece

Description

Composition
Active substance:
Amorolfine hydrochloride, 55.70 mg in terms of amorolfine 50.00 mg
Excipients:
Triacetin (glycerol triacetate) 10.50 mg
Methyl methacrylate, ethyl acrylate and trimetilammonioetilmetakrilata chloride copolymer [2: 0.2: 1] (ammonium methacrylate copolymer (Type A) (Eudragit RL 100)) 125.00 mg
Ethyl acetate 150.00 mg
Butyl acetate 50.00 mg
Anhydrous Ethanol to 1 ml
Description:
clear liquid from colorless to light yellow.
Product form:
Nail polish officinalis 5%.
2.5 ml vial of dark glass stopper and LDPE screw cap vial or dark glass screw cap with tamper-evident seal installed inside of the PET.
1 bottle together with instructions for use, the sachet 12 with cleaning tampons packed in a cardboard box, spatulas 10 of LDPE in the fixed range and fixed in a frame 12 Nail files are placed in a cardboard box.
Contraindications
Hypersensitivity to amorolfine or any of the components.
Dosage
50 mg / ml
Indications
Treatment of fungal nail infections caused by dermatophytes, yeasts and molds;
Prevention of fungal nail infections.
Interaction with other drugs
Not installed.
Overdose
Oflomil Lac – a preparation for external application with negligible systemic absorption and overdose unlikely.
If you accidentally taking the drug inside the stomach must be cleaned and immediately seek medical attention.
pharmachologic effect
Pharmacodynamics:
Antifungal agent for external use. It has fungistatic and fungicidal action due to damage of the cytoplasmic membrane by disrupting fungal sterol biosynthesis. It reduces the content of ergosterol accumulates content atypical sterically nonplanar sterols. It has a wide spectrum of action. Highly active against the most common and rare pathogens of fungal nail infections:
Dermatophytes: Trichophyton spp, Microsporum spp, Epidermophyton spp…
Yeasts: Candida spp, Cryptococcus spp, Malassezia spp… (Pityrosporum spp.)
Fungi: Alternaria spp, Scopulariopsis spp, Hendersonula spp…
Mushrooms from Dematiaceae family: Cladosporium spp, Fonsecaea spp, Wangiella spp…
Dimorphic fungi: Coccidioides spp, Histoplasma spp, Sporothrix spp…
Pharmacokinetics:
When applied on the nails penetrate the nail plate and further into the nail bed (almost entirely within the first 24 hours). The effective concentration is maintained in the affected nail plate within 7-10 days after the first application. Systemic absorption is negligible: plasma concentration is below the detection limit of determination methods (less than 0.5 ng / ml).
Pregnancy and breast-feeding
Given the limited data on the use of amorolfine in pregnant and lactating women, the use of the drug during pregnancy and lactation is not recommended.
Conditions of supply of pharmacies
Without recipe
side effects
In applying the drug Oflomil Lac undesirable reactions are rare. Such damaging the nail as a color change, destruction of the nail plate, nail fragility, can be the result of fungal nail infections.
All adverse reactions noted during application of the drug Oflomil Lac are presented in the table below in accordance with accepted classification system for organs and occurrence frequency: very often (> 1/10), often (> 1/100 –
special instructions
Nail files used for the treatment of the affected nails should not be used for the treatment of healthy nails;
Those working with organic solvents, should wear gloves to protect impermeable nail varnish coated;
During treatment, you should avoid using the overhead artificial nails;
The preparation contains ethanol, so too frequent or incorrect application it may cause irritation or dry skin around the nail;
The tampon comprises flammable.
Avoid exposure of the drug into the eyes, ears and mucous membranes. In case of contact with eyes, nail polish, rinse immediately with water. Patients with conditions that predispose to the development of fungal nail infections (violation of the peripheral circulation, diabetes, immune deficiencies), as well as patients with nail dystrophy or damaged nail plate, psoriasis and other chronic skin diseases should consult a doctor.
If the destruction or fungal lesions is subject to more than 2/3 of the nail plate, it is also necessary to see a doctor for the appointment of concomitant oral therapy.
Impact on the management of vehicles and mechanisms
It does not affect the ability to drive and use machines.
Storage conditions
Store in a dark place at a temperature not higher than 25 ° C. Do not freeze. Keep out of the reach of children.
Dosing and Administration
Outwardly. Apply to the affected nails of fingers or toes 1-2 times a week as follows:
1. Prior to application of the drug to remove the affected nail portions capabilities (particularly from its surface) with the appended nail files.
2. The surface of the nail, clean and degrease the supplied alcohol swab.
Before each subsequent application of the drug to also conduct processing affected nail and nail file and then delete the remaining lacquer layer alcohol swab.
3. Dip the spatula into the varnish. Spatula should be removed from the vial without touching his neck, do not wash the excess lacquer on the bottle neck.
4. Using a spatula apply varnish uniformly applied to the entire surface of the affected nail.
The above procedure was repeated for each of the affected nail.
5. Tightly close the bottle immediately after use.
6. Writing varnish to dry for approximately 3 minutes.
7. Wipe spatula swab used for nail cleaning, while avoiding contact of the treated nails and the tampon. Used tampon throw.
Application of decorative nail may not earlier than 10 minutes after application of nail varnish Oflomil. Repeated application of nail varnish Oflomil, must be carefully removed from the remainder of the decorative nail varnish and then with the accompanying nail files treat the affected area and remove the remaining nail lacquer layer alcohol swab.
After the procedure, wash your hands thoroughly. If the varnish is applied to the nails on the hands, wait until it is completely dry first.
After drying the varnish is allowed regular washing of hands and feet with soap. The treatment should continue as before regeneration nail and complete cure of the affected portion.
The average duration of treatment is 6 months for fingernails and 9-12 months for toenails.
In view of the slow growth of the nail plate the first signs of improvement may become visible only after 2-3 months of use of the drug. If there is no sign of improvement after 3 months it is recommended to consult a doctor.
Use in children
Clinical data on the use of the drug in pediatric patients lacking, so it should not be given to children
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist