Odeston tab 200mg 20 pieces

Description

Composition
Active substance:
Gimekromon (hymecromone).
Excipients:
Potato starch – 45 mg, gelatin – 3 mg of sodium lauryl sulfate – 1 mg magnesium stearate – 1 mg. 10 pieces. – blisters (2) – packs cardboard. 10 pieces. – blisters (5) – packs cardboard. 10 pieces. – blisters (10) – packs cardboard.
Description:
Tablets from white to white to yellowish white color, round, Valium, chamfered and engraved on one side of the letters «Ch». Gimekromon – 1 tablet 200 mg..
Product form:
Packing 20 pcs.
Contraindications
– obstruction of the bile ducts; – renal failure; – liver failure; – ulcerative colitis; – Crohn’s disease; – gastric ulcer and duodenal ulcer; – hemophilia; – child and adolescence to 18 years; – hypersensitivity to the drug.
Indications
– biliary dyskinesia and the sphincter of Oddi for hyperkinetic type; – nekalkulezny chronic cholecystitis, cholangitis, cholelithiasis; – condition after surgery on the gallbladder and biliary tract; – loss of appetite, nausea, constipation, vomiting (compared to hypo-secretion of bile).
Interaction with other drugs
With simultaneous use of morphine, causing a spasm of the sphincter of Oddi, reduces the effect Odeston. At simultaneous application with metoclopramide Odeston noted the mutual weakening of the action. Odeston increases effects of indirect anticoagulants.
Overdose
Currently, the cases of drug overdose Odeston were reported.
pharmachologic effect
Pharmacological group:
Cholagogue.
Pharmacodynamics:
Choleretic drug. Increases the formation and secretion of bile. It has a selective spasmolytic activity against bile duct and the sphincter of Oddi. The drug does not reduce the motility of the gastrointestinal tract and blood pressure. It reduces the stagnation of bile, prevents cholesterol crystallization and thereby the development of cholelithiasis.
Pharmacokinetics:
Absorption and distribution:
After intake of rapidly absorbed from the gastrointestinal tract. Cmax in the blood after oral administration is achieved in 2-3 hours. Low bound to plasma proteins.
Excretion: T1 / 2 is about 1 hour Excreted urine: about 93% – in the form of a glucuronate, 1.4% – in the form of sulfonate, 0.3% – unchanged..
Pregnancy and breast-feeding
No Information about the safety of gimekromona during pregnancy and lactation. Appointment Odeston during pregnancy and lactation (breastfeeding) is allowed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus or child.
Conditions of supply of pharmacies
Without recipe.
side effects
From the digestive system: diarrhea, flatulence, abdominal pain, ulceration gastrointestinal mucosa.
Other: allergic reactions, headache.
special instructions
Special precautions for the destruction of unused medicinal product should not be disposed of medicines down the drain or in household waste containers. For information on how to dispose of unused medication should ask the pharmacist. These measures will help to protect the environment.
Effects on ability to drive vehicles and management mechanisms
The drug has no effect on ability to drive and engage in other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
The drug should be kept out of reach of children at a temperature not higher than 25 ° C.
Dosing and Administration
The drug is administered orally 30 minutes before a meal. Adults appoint 200-400 mg 3 times / day. The daily dose – 1200 mg. The course of treatment – 2 weeks.
In the case of missing dosing should take the drug as soon as possible. If approaching the next administration, should not take the missed dose. Do not take a double dose to compensate missed.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist