Nurofen for children oral suspension 100mg / 5ml 200ml fl.plast with a syringe dosing strawberries

$5.15

Nurofen for children oral suspension 100mg / 5ml 200ml fl.plast with a syringe dosing strawberries

Quantity:

SKU: 01173004156 Categories: , , Tags: ,

Description

Composition
Active substance:
Ibuprofen 100 mg.
Excipients:
Polysorbate 80 0.5 mg, 0.5 mL glycerol, maltitol syrup 1.625 mL, 10 mg sodium saccharin, citric acid 20 mg Sodium citrate 25.45 mg Xanthan gum 37.5 mg, 5.5 mg sodium chloride, domiphen bromide 0.5 mg strawberry flavoring 12.5 mg 500244E, purified water to 5 ml.
Description:
White or nearly white suspension syrupy consistency with strawberry smell.
Product form:
Oral suspension [strawberry], 100 mg | 5 ml.
The PET bottle with a cap of low density polyethylene or polypropylene with a gasket containing 200 ml of suspension.
Each bottle complete with syringe – dispenser, is packed in a cardboard box with instructions for use.
Contraindications
Hypersensitivity to ibuprofen or any of the components included in the formulation.
Full or partial combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs.
Bleeding or perforation of ulcers of the gastrointestinal tract in history, triggered by the use of NSAIDs.
Erosive and ulcerative diseases of the gastrointestinal (including gastric ulcer and duodenal ulcer disease, Crohn’s disease, ulcerative colitis) or ulcer bleeding in the active phase or in history (two or more episodes of proven peptic ulcer or bleeding ulcer).
Severe liver failure or liver disease in active phase.
Renal failure, severe severity (creatinine clearance of 30 ml / min), confirmed hyperkalemia.
Decompensated heart failure, since the coronary artery bypass surgery.
Or other cerebrovascular bleeding.
Hemophilia and other bleeding disorders (including hypocoagulation), hemorrhagic diathesis.
Pregnancy (III trimester).
Fructose intolerance.
child’s body weight up to 5 kg.
Carefully:
In the presence of the conditions referred to in this section should consult a physician before using the product.
Simultaneous treatment with other NSAIDs, a history of a single episode of gastric ulcer or gastrointestinal bleeding ulcer, gastritis, enteritis, colitis, the presence of infection Helicobacter pylori, ulcerative colitis; bronchial asthma or allergic diseases in the acute stage or history – possibly bronchoconstriction; severe somatic disease, systemic lupus erythematosus or mixed connective tissue disease (Sharp’s syndrome) – increased risk of aseptic meningitis; chickenpox; renal failure, including during dehydration (creatinine clearance of 30-60 ml / min), fluid retention and edema, hepatic failure, arterial hypertension and / or heart failure, cerebrovascular disease, dyslipidemia / hyperlipidemia, diabetes, peripheral arterial diseases, blood unknown etiology (leukopenia, anemia); concomitant use of other drugs that may increase the risk of ulcers or bleeding, in particular, oral corticosteroids (including prednisone), anticoagulants (including warfarin), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) or antiplatelet agents (including acetylsalicylic acid, clopidogrel); pregnancy (I-II trimester), breastfeeding, older age.
Dosage
100 mg / 5 ml
Indications
Nurofen® suspension for children used in children from 3 months of age to 12 years for the symptomatic treatment as an antipyretic agent in acute respiratory diseases (including influenza), childhood infections, other infectious and inflammatory diseases and postprivivochnyh reactions accompanied by fever .
The drug is used as a symptomatic analgesic agent for pain syndrome weak or moderate intensity, including dental pain, headache, migraine, neuralgia, ear pain, sore throat, painful sprains, muscular pain, rheumatic pain, joint pain .
The drug is intended for the symptomatic therapy reduce pain and inflammation at the time of use, does not affect the progression of the disease.
Interaction with other drugs
It should avoid the simultaneous use of ibuprofen with the following drugs:
Acetylsalicylic acid: with the exception of low-dose acetylsalicylic acid (not more than 75 mg per day), prescribed by the doctor, since the combined use may increase the risk of side effects. With simultaneous use of ibuprofen reduces inflammatory and antiplatelet effect of acetylsalicylic acid (may increase the incidence of acute coronary insufficiency in patients receiving as antiplatelet agents acetylsalicylic acid, low dose, after initiation of ibuprofen).
Other NSAIDs, including selective inhibitors of COX-2 should avoid the simultaneous use of two or more drugs from the group of NSAIDs due to possible increased risk of side effects.
Precautions used simultaneously with the following drugs:
Anticoagulants and thrombolytic drugs: NSAIDs may enhance the effect of anticoagulants, particularly warfarin and thrombolytic agents.
Antihypertensive drugs (ACE inhibitors and angiotensin II) and diuretics NSAIDs may reduce efficacy of these groups. Diuretics and ACE inhibitors may increase the nephrotoxicity of NSAIDs.
Steroids: increased risk of gastrointestinal ulcers and gastrointestinal bleeding.
Antiplatelet agents and selective serotonin reuptake inhibitors: increased risk of gastrointestinal bleeding.
Cardiac glycosides: co-administration of NSAIDs and cardiac glycosides can lead to aggravation of heart failure, decreased glomerular filtration rate and an increase in concentration of cardiac glycosides in blood plasma.
of lithium drugs: there is evidence of the likelihood of increasing the concentration of lithium in blood plasma during treatment with NSAIDs.
Methotrexate: there is evidence of the likelihood of increasing concentration of methotrexate in the blood plasma during treatment with NSAIDs.
Cyclosporin: increased risk of nephrotoxicity with concomitant administration of NSAIDs and cyclosporine.
Mifepristone: NSAIDs should be started no earlier than 8-12 days after mifepristone administration as NSAIDs can reduce the efficacy of mifepristone.
Tacrolimus: while the appointment of NSAIDs and tacrolimus may increase the risk of nephrotoxicity.
Zidovudine: simultaneous application of NSAIDs and zidovudine could result in increased gematotoksichnosti. There is evidence of increased risk of haemarthrosis and hematoma in HIV-positive patients with hemophilia who received co-treatment with zidovudine and ibuprofen.
Quinolone antibiotics series: patients receiving collaborative care NSAIDs and quinolone antibiotics series, may increase the risk of seizures.
Overdose
In children, the symptoms of overdose may occur after ingestion of a dose exceeding 400 mg / kg body weight. In adults, a dose-dependent effect of an overdose is less pronounced. The half-life of the drug overdose is 1.5-3 hours.
Symptoms include nausea, vomiting, epigastric pain, or more rarely, diarrhea, tinnitus, headache and gastrointestinal bleeding. In more severe cases, there are manifestations of the central nervous system: drowsiness, rarely agitation, convulsions, disorientation, coma. In cases of severe poisoning can develop metabolic acidosis and increased prothrombin time, kidney failure, liver damage tissue, blood pressure, respiratory depression and cyanosis. Patients with asthma may increase the disease.
Treatment: symptomatic, with obligatory airway, ECG monitoring and vital signs up to the normalization condition of the patient. We recommend the use of activated charcoal oral or gastric lavage for 1 hours after administration of potentially toxic doses of ibuprofen. If ibuprofen has already been absorbed, it can be assigned to alkaline water with the aim of removing the acid derivative of ibuprofen kidney diuresis. Frequent or prolonged convulsions should be to stop the intravenous administration of diazepam or lorazepam. When deterioration of asthma recommend the use of bronchodilators.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug (NSAID)
Pharmacodynamics:
The mechanism of action of ibuprofen, the propionic acid derivative from the group of non-steroidal anti-inflammatory drugs (NSAIDs) is due to the inhibition of prostaglandin synthesis – mediators of pain, inflammation and hyperthermic response. Indiscriminately blocked cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), thereby inhibits the synthesis of prostaglandins. Furthermore, ibuprofen reversibly inhibits platelet aggregation. It has analgesic, antipyretic and anti-inflammatory effect. Analgesic effect is most pronounced with inflammatory pain. Preparation action extends to 8 hours.
Pharmacokinetics:
Absorption – high, rapidly and almost completely absorbed from the gastrointestinal tract (GIT) (linked to plasma proteins – 90%). After ingestion fasting adult ibuprofen found in blood plasma after 15 minutes, the maximum concentration (Cmax) in plasma of ibuprofen is achieved after 60 minutes. The drug with food can increase the time to reach maximum concentration (TSmax) of 1-2 hours. The half-life (T1 / 2) – 2 hr. Slowly into the joint cavity, it is retained in the synovial fluid, making it larger concentration than in blood plasma. After absorption of about 60% pharmacologically inactive R-form is transformed slowly into the active S-shape. It is metabolized in the liver. Excreted by the kidneys (in unmodified form are not more than 1%) and, to a lesser extent in the bile.
In limited studies, ibuprofen was detected in breast milk in very low concentrations.
Pregnancy and breast-feeding
Do not use this drug in the III trimester. Before using the product in the I-II trimester of pregnancy or lactation should consult a physician.
There is evidence that ibuprofen in small quantities can penetrate into breast milk without any adverse effects on infant health.
Conditions of supply of pharmacies
Without recipe.
side effects
The risk of side effects can be minimized, if you take a short course of the drug in the lowest effective dose needed to control symptoms.
Side effects are mainly dose dependent. The following adverse reactions were observed at short ibuprofen in doses not to exceed 1200 mg / day. In the treatment of chronic conditions and long-term use may cause other adverse reactions.
estimates of frequency of adverse reactions produced on the basis of the following criteria: (> 1/10), frequent (by> 1/100 to 1/1000 and 1/10 000
Blood disorders and lymphatic system
Very rare: disturbances of hematopoiesis (anemia, leukopenia, aplastic anemia, hemolytic anemia, thrombocytopenia, pancytopenia, agranulocytosis). The first symptoms of such disorders are fever, sore throat, superficial oral ulcers, flu-like symptoms, severe weakness, nosebleeds and bruising, bleeding, and bruising of unknown etiology.
Violations by the immune system
Infrequent: hypersensitivity reactions – nonspecific allergic reactions and anaphylactic reaction by the airway reactions (asthma, including its exacerbation, bronchoconstriction, dyspnea, dyspnea), skin reactions (pruritus, urticaria, purpura, angioedema, exfoliative and bullous dermatoses , including toxic epidermal necrolysis, Lyell’s syndrome, Stevens-Johnson syndrome, erythema multiforme), allergic rhinitis, eosinophilia.
Very rare: hypersensitivity severe reactions, including swelling of the face, tongue and throat, shortness of breath, tachycardia, hypotension (anaphylaxis, angioedema or severe anaphylactic shock).
Disorders of the gastrointestinal tract
Uncommon: abdominal pain, nausea, dyspepsia.
Rare: diarrhea, flatulence, constipation, vomiting.
Very rare: peptic ulcer, perforation or gastrointestinal bleeding, melena, hematemesis, ulcerative stomatitis, gastritis.
Frequency unknown: exacerbation of ulcerative colitis and Crohn’s disease.
Disorders of the liver and biliary tract
Very rare: liver function abnormalities.
Violations of the kidneys and the urinary tract
Rare: acute renal failure (compensated and decompensated), especially with prolonged use, in combination with increasing concentrations of urea in the blood plasma and the appearance of edemas, papillary necrosis.
Disorders of the nervous system
Uncommon: headache.
Very rare: aseptic meningitis (in patients with autoimmune diseases).
Violations of the cardiovascular system
Frequency is unknown: heart failure, peripheral edema, with prolonged use at increased risk of thrombotic complications (e.g., myocardial infarction, stroke), arterial blood pressure.
Violations of the respiratory system and organs of the mediastinum
Frequency not known: bronchial asthma, bronchospasm, dyspnea.
other
Very rare: edema, including peripheral.
Laboratory parameters hematocrit or hemoglobin (may be reduced)
Bleeding time (may be increased)
concentration in plasma glucose (may decrease)
creatinine clearance (may decrease)
plasma creatinine concentration (may be increased)
Activity “liver” enzymes (may be increased)
When side effects should stop taking the drug and consult a doctor.
special instructions
It is recommended to take the drug the maximum possible short-course, and in the lowest effective dose needed to control symptoms.
During long-term treatment is required to monitor patterns of peripheral blood and functional state of the liver and kidneys. When symptoms gastropathy shown careful control, comprising carrying esophagogastroduodenoscopy, total blood (hemoglobin), analysis of fecal occult blood. If necessary, the definition of 17-ketosteroids drug should be discontinued 48 hours prior to the study. During the period of treatment is not recommended intake of ethanol. The drug is contraindicated in patients with fructose intolerance, because it contains a part of maltitol.
Nurofen® for children can be used for children with diabetes, since the drug does not contain sugar. It does not contain dyes.
Patients with renal failure should consult a physician before using the product, since there is a risk of deterioration of renal function.
Patients with hypertension, including a history of and / or chronic heart failure, it is necessary to consult a physician before using the drug as the drug can cause fluid retention, hypertension and edema.
The use of NSAIDs in patients with varicella may be associated with an increased risk of severe septic complications infektsionnovospalitelnyh skin and subcutaneous fat (for example, necrotizing fasciitis). In this regard, it is recommended to avoid use of the drug varicella.
Effects on ability to transp. Wed. and fur .:
Patients marking dizziness, drowsiness, confusion or visual disturbances while taking ibuprofen, should avoid driving vehicles or machinery control.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Use within 6 months after opening the bottle.
Dosing and Administration
Nurofen® for children – suspension, specially designed for children. For ingestion. Patients with increased sensitivity of the stomach is recommended to take the drug at meal time.
Only for short-term use. Please read the instructions before taking the drug.
Before use, carefully shake the vial. For accurate measuring the dose supplied handy measuring syringe. 5 ml of the preparation contains 100 mg ibuprofen and 20 mg of ibuprofen in 1 ml.
Using the measuring syringe:
Firmly insert the measuring syringe into the neck of the bottle. Turn the bottle upside down and gently pull the piston down, picking up the slurry into a syringe to the desired mark. Return the bottle to its original position and remove the syringe, gently turning it. Place the syringe into the oral cavity and slowly press the piston, smoothly releasing the suspension.
After use, rinse the syringe with warm water and dry it out of reach of children.
Fever (fever) and pain:
The dosage for children depends on the child’s age and body weight. The maximum daily dose should not exceed 30 mg / kg body weight c intervals between doses of the drug 6-8 hours.
Children aged 3-6 months (weight of the child from 5 to 7.6 kg): 2.5 ml (50 mg) 3 times during 24 hours, not more than 7.5 ml (150 mg) per day.
Children aged 6-12 months (weight of the child 7.7 – 9 kg): 2.5 ml (50 mg) to 3-4 times within 24 hours, no more than 10 ml (200 mg) per day.
Children aged 1-3 years (child weighs 10 – 16 kg): 5.0 ml (100 mg) and 3 times over 24 hours, no more than 15 ml (300 mg) per day.
Children aged 4-6 years (baby weight 17 – 20 kg): 7.5 ml (150 mg) and 3 times over 24 hours, not more than 22.5 ml (450 mg) per day.
Children aged 7-9 years (baby weight 21 – 30 kg): 10 ml (200 mg) and 3 times over 24 hours, no more than 30 ml (600 mg) per day.
Children between the ages 10-12 years (baby weight 31 – 40 kg): 15 ml (300 mg) and 3 times over 24 hours, no more than 45 ml (900 mg) per day.
Duration of treatment – no more than 3 days. Do not exceed this dose.
If you are taking the drug for 24 hours (in children aged 3-5 months) or 3 days (in children aged 6 months and older) symptoms persist or intensify, it is necessary to stop treatment and seek medical advice.
Post-immunization fever:
Children under the age of 6 months: 2.5 ml (50 mg) formulation. If necessary, an additional 2.5 ml (50 mg) after 6 hours. Do not use more than 5 ml (100 mg) for 24 hours.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Nurofen

There are no reviews yet.

Add your review