Normase syrup 200ml vials

$5.51

Normase syrup 200ml vials

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Description

Composition
Active substance:
lactulose solution (in terms of lactulose) -66.7 g
Excipients:
citric acid 0.05 g, creamy flavor (№ 7 bis) 0.06 g Purified water – 100 ml.
Flavoring composition: propylene glycol, digidrokumarin, vanillin.
Description:
Clear, colorless or pale yellow with a brownish shade syrupy liquid.
Product form:
Syrup 667 mg / ml 200 ml brown vial during preparation of polyethylene terephthalate, closed screw cap of high density polyethylene. The vial with a polyethylene measured glass and instructions for use packed in a cardboard box.
Contraindications
-neperenosimost lactose;
– galactosemia;
– ileus;
– Hypersensitivity to any component of the formulation.
Patients with rare congenital disorders such as galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not use this drug.
Precautions – Patients with hepatic (pre) coma, diabetic; – undiagnosed rectal bleeding;
– colostomy, ileostomy.
Indications
Constipation: regulation of the physiological rhythm of emptying the colon.
Softening chair for medical purposes (hemorrhoids, post-surgery on the colon and in the anal area).
Hepatic encephalopathy: treatment and prevention of hepatic coma or precoma.
Interaction with other drugs
for interaction studies have been performed with other drugs.
Overdose
Symptoms: abdominal pain and diarrhea.
Treatment: drug discontinuation or dose reduction and correction of fluid and electrolyte balance in the case of a high fluid loss due to diarrhea or vomiting.
pharmachologic effect
Pharmacological group:
Laxative.
Pharmacodynamics:
Has hyperosmotic, gipoammoniemicheskoe, laxative effect, stimulates peristalsis, improves the absorption of calcium and phosphate salts.
Under the influence of the drug changes the flora of the large intestine (increase in the number of lactobacilli), which leads to increased acidity in the lumen of the colon and stimulate peristalsis. Along with this increased volume and softening of stools. As a result, the drug has a laxative effect, without affecting directly to the mucosa and the smooth muscles of the colon.
In hepatic encephalopathy and hepatic (pre) coma effect associated with inhibition of proteolytic bacteria by increasing the number of acidophilic bacteria (e.g., lactobacillus), conversion of ammonia into the ionic form due to acidification of colon contents emptying bowel owing to decrease in pH in the colon, the osmotic effect, and also reduction of nitrogen-containing toxic substances by stimulation of bacteria utilizing ammonia for synthesis of bacterial protein.
Lactulose as prebiotic substance enhances the growth of beneficial bacteria such as bifidobacteria and lactobacilli, whereas it becomes possible to suppress the growth of potentially pathogenic bacteria such as Clostridium and Escherichia coli, which provides a more favorable balance of intestinal flora.
Pharmacokinetics:
Absorption is low. After ingestion reaches the colon unaltered, where split intestinal flora. Completely metabolized at doses up to 40-75 ml; at higher dosage is partially excreted unchanged.
Pregnancy and breast-feeding
If necessary Normaze® can be used during pregnancy and lactation.
Conditions of supply of pharmacies
Without recipe.
side effects
In the early days of taking lactulose may cause flatulence. It generally disappears after a few days. In the case of high doses for long time in the treatment of hepatic encephalopathy patient can develop disorders of electrolyte balance due to diarrhea.
Disorders of the gastrointestinal tract:
Flatulence, abdominal pain, nausea, vomiting. When using high doses – may cause diarrhea.
Other violations:
Violations of water-electrolyte imbalance due to diarrhea.
special instructions
In the absence of therapeutic effect should consult a doctor for a few days.
Lactulose should be administered with caution to patients with lactose intolerance.
It should be borne in mind that Normaze® may contain minor amounts of bound sugars (e.g., lactose, galactose, fructose and epilaktoza).
Dosage usually applied in the treatment of constipation does not require correction for patients suffering from diabetes. When treating hepatic (pre) coma usually given the higher dose, which should be considered for patients with diabetes. Patients with rare congenital disorders such as galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not use this drug. When treating children laxatives should be used in exceptional cases and under medical supervision. Please be aware that during the treatment may occur reflex emptying disorders.
Impact on the ability to drive a car and other mechanisms
Use of the drug Normaze® no effect or has little effect on the ability to drive a car and mechanisms.
Storage conditions
Store at a temperature of from 15 to 25 C.
Do not freeze.
Keep out of the reach of children.
Dosing and Administration
The drug is intended for oral administration.
A solution of lactulose can be taken both in diluted and undiluted. It is necessary to immediately swallow received a single dose without delaying the mouth. All dosage should be individualized.
In case of appointment of a single daily dose, it must be taken at one and the same time, for example at breakfast time.
During therapy, laxatives are advised to take plenty of fluids (1.5-2 liters, equal to 6-8 glasses) per day.
The dosage for the treatment of constipation or stool softener for medical purposes: lactulose daily dose can be administered once or by dividing it into two, using a measuring cup.
The initial dose may be adjusted to a maintenance dose, depending on the reaction to the drug. The therapeutic effect may appear after 2-3 days after initiation of treatment.
Age | The initial daily dose | Supportive daily dose
Adults and adolescents | Ml 15-45 | 10-30 ml
Children 7-14 years | 15 ml | 10 ml -15
Children 1-6 years | 5-10 ml | 5-10 ml
Children up to 1 year | to 5 ml | to 5 ml
Duration of treatment 4 weeks to 3-4 months.
The dosage for the treatment of hepatic coma and precoma:
Initial dose 3-4 times a day for 30-45 ml.
Then move on individually tailored maintenance dose so that the upholstered chair was the most 2-3 times a day.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

DR.REDDIS

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