Nifural caps. 200mg 16 pieces

Description

Composition
Active substance:
1 capsule contains: nifuroxazide 100/200 mg ;.
Excipients:
Sugar (sucrose), category “extra”, corn starch, microcrystalline cellulose, magnesium stearate; hard gelatin capsule: the capsule body and cap – titanium dioxide, iron oxide yellow, gelatin.
Description:
Hard gelatin capsules № 2 (for 100 mg dosage) or № 0 (for a dosage of 200 mg) with a housing and a lid of a yellow color. The contents of capsules – powder mixture and the yellow pellets.
Product form:
Capsules 100 mg and 200 mg.
By 7, 8, 10 or 14 capsules in blisters of PVC film and aluminum foil printed patent.
1, 2, 4 blisters together with instructions for use placed in a pile of cardboard.
Contraindications
Hypersensitivity to nifuroxazide, nitrofuran derivatives or any of the excipients of the drug, lack sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption, pregnancy, children under 3 years.
Dosage
200 mg
Indications
Acute bacterial diarrhea flowing without deterioration in general condition, fever, intoxication.
Interaction with other drugs
Not recommended simultaneous use with drugs that cause development disulfiramopodobnyh reactions, drugs, depressing the function of the central nervous system. If you are taking any other medications (including over the counter) before using consult your doctor.
Overdose
Symptoms of overdose are not known. Treatment is symptomatic.
pharmachologic effect
Pharmacological group:
The antimicrobial agent-nitrofuran.
Pharmacodynamics:
Nifuroxazide – intestinal antiseptic, a derivative of 5-nitrofuran, highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp, Shigella spp; Clostridium perfingens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp. Very sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae and Proteus indologenes. Resistant to nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp.
Nifuroxazide presumably inhibits dehydrogenase activity and protein synthesis in bacterial cells. Does not cause occurrence of drug-resistant strains are also cross-resistance was observed with other antibacterial agents. The efficiency of nifuroxazide is independent of pH, exists in the lumen of the intestine or the sensitivity of microorganisms to antibiotics. It does not affect the composition of the normal bacterial flora of the digestive tract. In acute bacterial diarrhea restoring intestinal eubioz. When infected by viruses enterotropnymi prevents the development of bacterial superinfection.
Pharmacokinetics:
After oral administration nifuroxazide practically not absorbed from the digestive tract and its antibacterial effect has only in the lumen of the intestine. Nifuroxazide output intestine: 20% unchanged, and the rest kolichesvo nifuroxazide – chemically modified.
Pregnancy and breast-feeding
Pregnancy
In animal studies there was no evidence of teratogenic effects. However, as a precautionary measure to take nifuroxazide during pregnancy is not recommended.
Breastfeeding
During the breastfeeding period possible continuation of breastfeeding in the case of a short course of treatment with the drug. It is necessary to consult with your doctor.
Conditions of supply of pharmacies
Without a prescription.
side effects
Allergic reactions (rash, urticaria, angioneurotic edema, anaphylactic shock). If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
In the treatment of diarrhea at the same time with the therapy should be carried out nifuroxazide rehydration therapy.
In the case of bacterial diarrhea with signs of systemic damage (deterioration of general condition, fever, symptoms of intoxication or infection) should consult a doctor to decide on the appointment of antimicrobial drugs for systemic effects.
During therapy, a drug banned alcohol.
If you have symptoms of an allergic reaction (including shortness of breath, rash, pruritus) discontinue use of the drug.
Note that the dosage of 1 capsule contains 100 mg 0.036 g sugar (sucrose), which is 0.0036 XE; 1 capsule contains a dose of 200 mg 0,071 g of sugar, accounting 0.0071 XE.
The drug has no effect on the ability to drive vehicles and mechanisms.
Storage conditions
Store in the dark, the reach of children at a temperature not higher than 25 C.
Dosing and Administration
It is used inside. The capsule should be swallowed whole with a little water.
Children from 3 to 6: 2 capsules of 100 mg or 1 capsule of 200 mg three times a day (the interval between doses 8 hours).
Children 6 to 18 years: 2 capsules of 100 mg or 1 capsule of 200 mg 3-4 times a day (the interval between doses 6-8 hours).
Adults: 2 capsules of 100 mg or 1 capsule 200 mg 4 times a day (the interval between doses 6 hours).
The duration of treatment 5-7 days, but no more than 7 days. If within the first 3 days of no improvement, you should consult your doctor.
Use drug only according to the application and in those doses which are specified in the instruction. If necessary, please consult your physician before using the drug.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist