Nazik Nazal Spray. scrapper. children 0.05 + 5mg / dose 10ml vial

Description

Composition
Active substance:
1 dose comprises Xylometazoline hydrochloride – 0.05 mg, dexpanthenol – 5 mg.
Excipients:
Benzalkonium chloride (as a 50% solution) – 0.04 mg Potassium dihydrogen phosphate – 0.853 mg, sodium hydrogen phosphate – 0.027 mg dodecahydrate Purified water – 94.03 mg.
Description:
Transparent, colorless liquid.
Product form:
Spray 10 ml.
Contraindications
Increased sensitivity to the drug, hypertension, tachycardia, expressed atherosclerosis, hyperthyroidism, glaucoma, atrophic rhinitis, surgical interventions in the meninges (history), sicca.
Children under 2 years old.
Dosage
0.05 mg + 5 mg / dose
Indications
Applied with acute respiratory diseases with symptoms of rhinitis, acute allergic rhinitis, vasomotor rhinitis, sinusitis, otitis media with (in combination therapy to reduce the swelling of nasal mucosa) to facilitate rinoskopii, restore impaired nasal breathing after surgery in the nasal cavity.
Interaction with other drugs
Concomitant use of MAO inhibitors and tricyclic antidepressants may lead to increased blood pressure due to the impact of these drugs on the cardiovascular system.
Overdose
In cases of overdose or accidental oral administration may experience the following symptoms: mydriasis, nausea, vomiting, cyanosis, fever, convulsions, cardiac arrhythmias, heart failure, hypertension, pulmonary edema, impaired respiratory function, hallucinations.
Patients may also appear symptoms of oppression on the part of the central nervous system, accompanied by drowsiness, decrease in body temperature, bradycardia, shock, respiratory arrest and coma.
Treatment.
The use of activated charcoal, gastric lavage, oxygen ventilation. To reduce the blood pressure is prescribed 5 mg phentolamine in 0.9% sodium chloride solution by slow intravenous injection or orally 100 mg of phentolamine. Vasoconstrictor drugs are contraindicated. If necessary apply antipyretic and anticonvulsants.
pharmachologic effect
Pharmacological group:
Decongestant agent.
Pharmacodynamics:
Xylometazoline refers to a group of local vasoconstrictive agents (decongestants) with alpha-Adrenomimeticalkie activity causes vasoconstriction of nasal mucosa, nasal restores patency facilitates nasal breathing. Effect of the drug typically occurs within a few minutes after its application and continues until 10 hours.
Dexpanthenol – Vitamin B group – a derivative of pantothenic acid. Dexpanthenol is converted in the body to pantothenic acid, which is a component of coenzyme A, and is involved in the processes of acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, corticosteroids, porphyrins; It stimulates the regeneration of the skin, mucous membranes, normalizes cell metabolism, accelerates mitosis and increases the strength of collagen fibers. Provides regenerating, metabolic and weak anti-inflammatory action.
Pharmacokinetics:
Xylometazoline when applied topically practically not absorbed, the plasma concentrations are so small that they can not identify with modern analytical methods.
Dexpanthenol for topical application of skin is rapidly absorbed and converted into pantothenic acid, binds to plasma proteins (mostly with beta-globulin and albumin). Its concentration in the blood – 0.5-1 mg / l in the blood serum – 100 g / l. Pantothenic acid is not subjected to metabolism in the body (except for inclusion in Co-A) is output unchanged.
Conditions of supply of pharmacies
Without recipe.
side effects
With frequent and / or prolonged use – irritation and / or dryness of the mucosa of the nasopharynx, burning, tingling, sneezing, hypersecretion, allergic reactions, edema of the nasal mucosa, vomiting, headache, dry rhinitis, palpitations, increased blood pressure, insomnia, visual impairment, depression (with prolonged use of high doses).
special instructions
Before use, clean the nasal passages. Do not apply more than 7 days. The duration of the drug in children is established after consultation with the doctor.
During the period of the drug should be taken when performing potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
At a temperature of not higher than 25 C.
In the reach of children.
Dosing and Administration
intranasally
For children from 2 to 6 years
When using a pump action bottle dosing device packaged separately:
Remove the pump-action dispensing device from its packaging. Uncorking vial is screwed onto the neck of the vial dispenser to remove a protective cap. The vial is ready to use. Prior to starting the spray repeatedly press a pump dispensing device until a uniform dispersion.
When using a bottle with a built-in pump-action dispensing device:
Remove the cap from the integrated pump-action dispensing device. The vial is ready to use.
Prior to starting the spray several times to press the inside pump-action dispensing apparatus until a uniform dispersion. In the application of spray bottle must be held upright.
During the injection you need to easily inhale nose. One injection into each nostril 3-4 times a day. Duration of therapy 5 – 7 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist